PSMB8-AS1
Species: Homo sapiens
Position: chr6: 4038373-32846500
Known as: PSMB8-AS1 , ENSG00000204261
Transcript: NR_037173 , NR_037174 , NR_037175 , NR_037176
Sequence: Download
Description:
PSMB8-AS1 repression inhibits influenza virus replication. PSMB8-AS1 was induced by different influenza virus strains and type I IFN. The role of PSMB8-AS1 may not be only limited to viral pathogenesis but may be involved in modulation of IFN response.
sgRNAs
| sgRNA_ID | Sequence | Position (Chr) | Position (Lnc) | Length | PAM | Type | Validity | Cell line | Note | Ref. |
|---|---|---|---|---|---|---|---|---|---|---|
| sgRNA1 | GAAGCCGGTCCCCAGTGTGA | 32844142-32844161(-) | gene body (near 3') | 20 | TGG | CRISPRi | Experimental validated | A549 | NA | [1] |
| sgRNA2 | GCGGACAGATCTCTGGGTGC | 32844006-32844025(-) | gene body (near 3') | 20 | TGG | CRISPRi | Experimental validated | A549 | NA | [1] |
| sgRNA3 | GATCTGTCCGCTCTCGGAGG | 32844015-32844034(+) | gene body (near 3') | 20 | AGG | CRISPRi | Experimental validated | A549 | NA | [1] |
GBrowser
Links
Reference
1. More S, Zhu Z, Lin K, Huang C, Pushparaj S, et al. (2019). Long non-coding RNA PSMB8-AS1 regulates influenza virus replication. RNA Biol 16(3): 340-353.
