ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 31/403 79/7206 3.59855859216e-19 ko04976 Bile secretion 21/403 80/7206 1.41784512397e-09 ko04974 Protein digestion and absorption 23/403 96/7206 1.63943700243e-09 ko04977 Vitamin digestion and absorption 9/403 22/7206 1.26995128452e-06 ko05166 HTLV-I infection 1/403 292/7206 1.39697803382e-06 ko00983 Drug metabolism - other enzymes 11/403 42/7206 1.29372200188e-05 ko04975 Fat digestion and absorption 10/403 35/7206 1.39045227463e-05 ko04614 Renin-angiotensin system 7/403 18/7206 3.01812424878e-05 ko04972 Pancreatic secretion 18/403 111/7206 3.7736714435e-05 ko04978 Mineral absorption 10/403 40/7206 4.98961607083e-05 ko00380 Tryptophan metabolism 11/403 50/7206 7.52499527604e-05 ko05016 Huntington's disease 1/403 215/7206 0.000108082095984 ko04080 Neuroactive ligand-receptor interaction 43/403 423/7206 0.000110852045731 ko05150 Staphylococcus aureus infection 9/403 36/7206 0.000119225179025 ko02010 ABC transporters 9/403 39/7206 0.00023109130597 ko00260 Glycine, serine and threonine metabolism 10/403 48/7206 0.000257509632958 ko00340 Histidine metabolism 7/403 25/7206 0.000323942501236 ko00350 Tyrosine metabolism 8/403 33/7206 0.000359352750878 ko04740 Olfactory transduction 13/403 80/7206 0.000440192110847 ko00120 Primary bile acid biosynthesis 6/403 20/7206 0.00058373202379 ko04744 Phototransduction 8/403 36/7206 0.000675691476017 ko05200 Pathways in cancer 12/403 492/7206 0.000738509045105 ko04310 Wnt signaling pathway 1/403 181/7206 0.000764008837879 ko04950 Maturity onset diabetes of the young 7/403 29/7206 0.000866028018403 ko04360 Axon guidance 3/403 233/7206 0.00125253909404 ko04550 Signaling pathways regulating pluripotency of stem cells 1/403 165/7206 0.00157879733168 ko00140 Steroid hormone biosynthesis 8/403 41/7206 0.00166927392551 ko00360 Phenylalanine metabolism 5/403 17/7206 0.00188565755508 ko00830 Retinol metabolism 8/403 42/7206 0.00196350376212 ko05012 Parkinson's disease 1/403 155/7206 0.0022384135209 ko05203 Viral carcinogenesis 5/403 277/7206 0.00296713136639 ko00982 Drug metabolism - cytochrome P450 7/403 37/7206 0.00388095429074 ko04964 Proximal tubule bicarbonate reclamation 6/403 29/7206 0.00466453543058 ko05204 Chemical carcinogenesis 8/403 48/7206 0.00468308757194 ko05010 Alzheimer's disease 3/403 202/7206 0.00493056079769 ko03040 Spliceosome 1/403 145/7206 0.00501528313038 ko04110 Cell cycle 1/403 145/7206 0.00501528313038 ko00591 Linoleic acid metabolism 5/403 22/7206 0.0063683751824 ko00053 Ascorbate and aldarate metabolism 5/403 22/7206 0.0063683751824 ko04120 Ubiquitin mediated proteolysis 1/403 138/7206 0.00730735479893 ko00410 beta-Alanine metabolism 6/403 35/7206 0.0120155466368 ko00500 Starch and sucrose metabolism 6/403 35/7206 0.0120155466368 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/403 182/7206 0.0133991732466 ko04150 mTOR signaling pathway 3/403 184/7206 0.0135498848354 ko04141 Protein processing in endoplasmic reticulum 3/403 184/7206 0.0135498848354 ko03320 PPAR signaling pathway 9/403 69/7206 0.014062001108 ko00643 Styrene degradation 2/403 4/7206 0.0173615007506 ko00250 Alanine, aspartate and glutamate metabolism 6/403 38/7206 0.0177580291241 ko00630 Glyoxylate and dicarboxylate metabolism 6/403 38/7206 0.0177580291241 ko05161 Hepatitis B 3/403 173/7206 0.0185228046926 ko05169 Epstein-Barr virus infection 4/403 206/7206 0.0194132151376 ko04742 Taste transduction 8/403 61/7206 0.0194684726429 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/403 11/7206 0.0204623967321 ko00980 Metabolism of xenobiotics by cytochrome P450 6/403 40/7206 0.0224901975098 ko04114 Oocyte meiosis 2/403 139/7206 0.0243401634823 ko00100 Steroid biosynthesis 4/403 21/7206 0.0270361918691 ko00232 Caffeine metabolism 2/403 5/7206 0.0278722211913 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/403 5/7206 0.0278722211913 ko04973 Carbohydrate digestion and absorption 6/403 42/7206 0.0280048925263 ko04144 Endocytosis 10/403 342/7206 0.0288986586296 ko04350 TGF-beta signaling pathway 1/403 103/7206 0.0303401837343 ko00052 Galactose metabolism 5/403 33/7206 0.0347388930117 ko04722 Neurotrophin signaling pathway 3/403 160/7206 0.0353175634619 ko00770 Pantothenate and CoA biosynthesis 3/403 14/7206 0.0398681955534 ko00620 Pyruvate metabolism 6/403 46/7206 0.04154457825 ko05211 Renal cell carcinoma 1/403 96/7206 0.043694919389 ko04658 Th1 and Th2 cell differentiation 1/403 96/7206 0.043694919389 ko05100 Bacterial invasion of epithelial cells 1/403 99/7206 0.0442262117067 ko00270 Cysteine and methionine metabolism 6/403 47/7206 0.0454753609468 ko04218 Cellular senescence 4/403 177/7206 0.0466624589771 ko04217 Necroptosis 4/403 178/7206 0.0466840066187 ko05168 Herpes simplex infection 4/403 182/7206 0.0475094307852 ko04660 T cell receptor signaling pathway 2/403 124/7206 0.0477902628666 ko04142 Lysosome 3/403 151/7206 0.0482055109142