ko pathway ratio_in_study ratio_in_pop p_value ko04650 Natural killer cell mediated cytotoxicity 17/308 97/7206 5.76632969015e-07 ko04380 Osteoclast differentiation 19/308 134/7206 3.56181737937e-06 ko04710 Circadian rhythm 10/308 43/7206 9.59116454423e-06 ko05340 Primary immunodeficiency 8/308 30/7206 2.61142446693e-05 ko04659 Th17 cell differentiation 15/308 106/7206 3.93412386899e-05 ko04658 Th1 and Th2 cell differentiation 14/308 96/7206 5.07049324879e-05 ko04070 Phosphatidylinositol signaling system 15/308 112/7206 7.55093290374e-05 ko04664 Fc epsilon RI signaling pathway 12/308 77/7206 9.0587525918e-05 ko05140 Leishmaniasis 11/308 75/7206 0.00030796245991 ko05152 Tuberculosis 19/308 187/7206 0.000376948222573 ko04137 Mitophagy - animal 11/308 82/7206 0.000674625955193 ko04660 T cell receptor signaling pathway 14/308 124/7206 0.000783650655379 ko05145 Toxoplasmosis 14/308 126/7206 0.000919352967936 ko04620 Toll-like receptor signaling pathway 12/308 100/7206 0.00107475969426 ko04662 B cell receptor signaling pathway 11/308 88/7206 0.00122797444564 ko00590 Arachidonic acid metabolism 8/308 52/7206 0.0014800755245 ko04060 Cytokine-cytokine receptor interaction 18/308 191/7206 0.00150893527795 ko05230 Central carbon metabolism in cancer 10/308 81/7206 0.00222968322327 ko04611 Platelet activation 16/308 163/7206 0.00230344198325 ko05164 Influenza A 16/308 167/7206 0.00262935609498 ko05330 Allograft rejection 5/308 24/7206 0.00300069267713 ko04630 Jak-STAT signaling pathway 13/308 132/7206 0.00407990021708 ko05310 Asthma 4/308 17/7206 0.00500687644812 ko05162 Measles 12/308 120/7206 0.00504328018845 ko04640 Hematopoietic cell lineage 8/308 64/7206 0.0055905864654 ko04068 FoxO signaling pathway 15/308 167/7206 0.00568957604873 ko04666 Fc gamma R-mediated phagocytosis 12/308 122/7206 0.00575610229256 ko05320 Autoimmune thyroid disease 5/308 29/7206 0.00704043170637 ko05321 Inflammatory bowel disease (IBD) 7/308 56/7206 0.00934005317915 ko05142 Chagas disease (American trypanosomiasis) 12/308 130/7206 0.0126857107369 ko04514 Cell adhesion molecules (CAMs) 12/308 130/7206 0.0126857107369 ko00562 Inositol phosphate metabolism 9/308 89/7206 0.0133672083286 ko05231 Choline metabolism in cancer 12/308 134/7206 0.014584008987 ko04022 cGMP-PKG signaling pathway 17/308 216/7206 0.0149992742312 ko01524 Platinum drug resistance 8/308 76/7206 0.0153436420634 ko04622 RIG-I-like receptor signaling pathway 7/308 62/7206 0.0159494954969 ko04711 Circadian rhythm - fly 3/308 13/7206 0.0160721983154 ko04612 Antigen processing and presentation 8/308 77/7206 0.0165091322677 ko04672 Intestinal immune network for IgA production 5/308 37/7206 0.01958420135 ko04919 Thyroid hormone signaling pathway 12/308 143/7206 0.0208842708302 ko04064 NF-kappa B signaling pathway 9/308 96/7206 0.0210673219587 ko03040 Spliceosome 1/308 145/7206 0.0215813512467 ko04745 Phototransduction - fly 5/308 38/7206 0.0217874059835 ko04922 Glucagon signaling pathway 11/308 128/7206 0.0242509816023 ko00980 Metabolism of xenobiotics by cytochrome P450 5/308 40/7206 0.0266624631518 ko05416 Viral myocarditis 6/308 55/7206 0.0289869106428 ko04062 Chemokine signaling pathway 15/308 201/7206 0.0320636369351 ko00051 Fructose and mannose metabolism 5/308 42/7206 0.0321827711166 ko05168 Herpes simplex infection 14/308 182/7206 0.0375752313547 ko05332 Graft-versus-host disease 3/308 18/7206 0.0391899315275 ko05144 Malaria 5/308 45/7206 0.0417145505327 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/308 191/7206 0.0440426692882 ko03010 Ribosome 1/308 129/7206 0.0450944678563 ko00592 alpha-Linolenic acid metabolism 3/308 19/7206 0.0451087636983 ko04722 Neurotrophin signaling pathway 12/308 160/7206 0.0479509761333 ko04730 Long-term depression 7/308 78/7206 0.0483422703614