ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	71/475	145/7206	3.21195950613e-46
ko04110	Cell cycle	48/475	145/7206	3.89867753245e-22
ko03030	DNA replication	25/475	38/7206	3.94998591403e-21
ko03008	Ribosome biogenesis in eukaryotes	31/475	79/7206	4.30873576689e-17
ko04111	Cell cycle - yeast	33/475	90/7206	4.57292696518e-17
ko05322	Systemic lupus erythematosus	39/475	151/7206	4.26759015437e-14
ko03410	Base excision repair	18/475	38/7206	3.9475564792e-12
ko03013	RNA transport	38/475	166/7206	5.36875281448e-12
ko04113	Meiosis - yeast	23/475	70/7206	3.9852953027e-11
ko03015	mRNA surveillance pathway	26/475	93/7206	1.2509424613e-10
ko00240	Pyrimidine metabolism	28/475	110/7206	2.6873365242e-10
ko03430	Mismatch repair	12/475	22/7206	2.07075274942e-09
ko05034	Alcoholism	41/475	238/7206	8.30226223094e-09
ko03420	Nucleotide excision repair	16/475	46/7206	1.5507795189e-08
ko04144	Endocytosis	2/475	342/7206	3.36662210934e-08
ko03460	Fanconi anemia pathway	14/475	51/7206	3.24359922835e-06
ko05203	Viral carcinogenesis	38/475	277/7206	1.74865172048e-05
ko04072	Phospholipase D signaling pathway	1/475	197/7206	3.05992653787e-05
ko04060	Cytokine-cytokine receptor interaction	1/475	191/7206	4.52866730856e-05
ko03440	Homologous recombination	11/475	41/7206	4.69368871061e-05
ko04024	cAMP signaling pathway	4/475	279/7206	6.24231499691e-05
ko03020	RNA polymerase	9/475	29/7206	6.63647910625e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	1/475	182/7206	0.000102026581169
ko05202	Transcriptional misregulation in cancer	27/475	188/7206	0.000126944673846
ko04062	Chemokine signaling pathway	2/475	201/7206	0.000230878378669
ko04218	Cellular senescence	25/475	177/7206	0.000289120543684
ko03018	RNA degradation	15/475	84/7206	0.00033306061679
ko04022	cGMP-PKG signaling pathway	3/475	216/7206	0.000422873167043
ko05152	Tuberculosis	2/475	187/7206	0.000473429001124
ko00230	Purine metabolism	25/475	194/7206	0.00106889873371
ko05168	Herpes simplex infection	24/475	182/7206	0.00116375344947
ko04726	Serotonergic synapse	1/475	137/7206	0.00147178986745
ko04713	Circadian entrainment	1/475	136/7206	0.00147270136538
ko04071	Sphingolipid signaling pathway	2/475	162/7206	0.00202680547197
ko05142	Chagas disease (American trypanosomiasis)	1/475	130/7206	0.0021548650337
ko04380	Osteoclast differentiation	1/475	134/7206	0.00222333696773
ko05166	HTLV-I infection	33/475	292/7206	0.00232983154853
ko04141	Protein processing in endoplasmic reticulum	3/475	184/7206	0.0024271234863
ko04270	Vascular smooth muscle contraction	2/475	154/7206	0.00290041552421
ko04722	Neurotrophin signaling pathway	2/475	160/7206	0.00307123517018
ko04725	Cholinergic synapse	2/475	160/7206	0.00307123517018
ko05145	Toxoplasmosis	1/475	126/7206	0.00316597743581
ko04261	Adrenergic signaling in cardiomyocytes	4/475	205/7206	0.00380171606432
ko04530	Tight junction	5/475	228/7206	0.00395507433053
ko04670	Leukocyte transendothelial migration	2/475	151/7206	0.0041905791905
ko04668	TNF signaling pathway	1/475	120/7206	0.00462277687922
ko04912	GnRH signaling pathway	1/475	122/7206	0.00474777972818
ko04330	Notch signaling pathway	10/475	62/7206	0.00680750287544
ko04911	Insulin secretion	1/475	117/7206	0.00706778028804
ko04145	Phagosome	3/475	162/7206	0.00947805323039
ko04611	Platelet activation	3/475	163/7206	0.00957178756233
ko04659	Th17 cell differentiation	1/475	106/7206	0.00973668738007
ko04728	Dopaminergic synapse	4/475	185/7206	0.00991145969763
ko04360	Axon guidance	6/475	233/7206	0.00995073579033
ko04921	Oxytocin signaling pathway	5/475	209/7206	0.0100518076898
ko04972	Pancreatic secretion	1/475	111/7206	0.0102898632289
ko04915	Estrogen signaling pathway	2/475	131/7206	0.0119440904324
ko04630	Jak-STAT signaling pathway	2/475	132/7206	0.0120155572426
ko04933	AGE-RAGE signaling pathway in diabetic complications	2/475	135/7206	0.0125084710901
ko04114	Oocyte meiosis	17/475	139/7206	0.0138320327685
ko04510	Focal adhesion	7/475	240/7206	0.0165140745899
ko04660	T cell receptor signaling pathway	2/475	124/7206	0.0168688603964
ko04142	Lysosome	3/475	151/7206	0.0186083604022
ko04650	Natural killer cell mediated cytotoxicity	1/475	97/7206	0.0209390603708
ko00564	Glycerophospholipid metabolism	1/475	99/7206	0.0217024090017
ko05146	Amoebiasis	1/475	99/7206	0.0217024090017
ko04750	Inflammatory mediator regulation of TRP channels	2/475	122/7206	0.0246824688417
ko04662	B cell receptor signaling pathway	1/475	88/7206	0.0296598358802
ko04810	Regulation of actin cytoskeleton	9/475	264/7206	0.0311529161009
ko05231	Choline metabolism in cancer	3/475	134/7206	0.0345309163549
ko04014	Ras signaling pathway	10/475	279/7206	0.0361448249058
ko04015	Rap1 signaling pathway	10/475	278/7206	0.036160742359
ko04550	Signaling pathways regulating pluripotency of stem cells	18/475	165/7206	0.0367050374873
ko04010	MAPK signaling pathway	12/475	321/7206	0.0373107560905
ko04371	Apelin signaling pathway	5/475	177/7206	0.0441617143431
ko05169	Epstein-Barr virus infection	21/475	206/7206	0.0445132359096
ko04924	Renin secretion	1/475	86/7206	0.0445520789461
ko04918	Thyroid hormone synthesis	1/475	86/7206	0.0445520789461
ko05160	Hepatitis C	4/475	153/7206	0.0462853612677
ko04925	Aldosterone synthesis and secretion	2/475	105/7206	0.046905951871
ko01200	Carbon metabolism	3/475	128/7206	0.0473832996203
ko04540	Gap junction	3/475	128/7206	0.0473832996203