ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	133/884	423/7206	2.95057883467e-27
ko04724	Glutamatergic synapse	64/884	152/7206	8.4436070802e-21
ko05033	Nicotine addiction	36/884	56/7206	5.6564329832e-20
ko04713	Circadian entrainment	54/884	136/7206	2.29219418925e-16
ko04728	Dopaminergic synapse	61/884	185/7206	6.57012857305e-14
ko04020	Calcium signaling pathway	77/884	265/7206	8.57669052865e-14
ko04727	GABAergic synapse	43/884	110/7206	5.30128170169e-13
ko05032	Morphine addiction	43/884	110/7206	5.30128170169e-13
ko04723	Retrograde endocannabinoid signaling	56/884	175/7206	2.92653503657e-12
ko04911	Insulin secretion	43/884	117/7206	6.20433995377e-12
ko04921	Oxytocin signaling pathway	62/884	209/7206	8.8508803229e-12
ko04024	cAMP signaling pathway	75/884	279/7206	1.16454907222e-11
ko04725	Cholinergic synapse	49/884	160/7206	3.9500215521e-10
ko04721	Synaptic vesicle cycle	31/884	80/7206	1.26152571688e-09
ko04726	Serotonergic synapse	43/884	137/7206	2.06102108292e-09
ko05031	Amphetamine addiction	31/884	91/7206	4.54362313424e-08
ko04261	Adrenergic signaling in cardiomyocytes	53/884	205/7206	6.19022444161e-08
ko04720	Long-term potentiation	32/884	99/7206	1.12827834036e-07
ko05322	Systemic lupus erythematosus	2/884	151/7206	9.76838987423e-07
ko03010	Ribosome	1/884	129/7206	1.13723013664e-06
ko04022	cGMP-PKG signaling pathway	52/884	216/7206	1.32714800618e-06
ko04745	Phototransduction - fly	16/884	38/7206	3.69328801641e-06
ko04742	Taste transduction	21/884	61/7206	5.63011176911e-06
ko05203	Viral carcinogenesis	12/884	277/7206	5.96144628017e-06
ko04744	Phototransduction	15/884	36/7206	8.70544985147e-06
ko04970	Salivary secretion	28/884	95/7206	9.09494821431e-06
ko03040	Spliceosome	3/884	145/7206	1.58136564164e-05
ko05168	Herpes simplex infection	6/884	182/7206	2.95636217055e-05
ko05164	Influenza A	5/884	167/7206	3.66374662138e-05
ko04010	MAPK signaling pathway	64/884	321/7206	5.5892356144e-05
ko04971	Gastric acid secretion	26/884	98/7206	0.000123396049285
ko04925	Aldosterone synthesis and secretion	27/884	105/7206	0.000129537527267
ko04730	Long-term depression	22/884	78/7206	0.000147831315203
ko04922	Glucagon signaling pathway	31/884	128/7206	0.000176387728986
ko04060	Cytokine-cytokine receptor interaction	8/884	191/7206	0.00018773944197
ko04740	Olfactory transduction	22/884	80/7206	0.00019657927897
ko05014	Amyotrophic lateral sclerosis (ALS)	21/884	74/7206	0.000205275062467
ko05162	Measles	3/884	120/7206	0.000212860674921
ko04260	Cardiac muscle contraction	25/884	98/7206	0.000268211778219
ko04630	Jak-STAT signaling pathway	4/884	132/7206	0.000390682154482
ko04710	Circadian rhythm	14/884	43/7206	0.000398331857659
ko04070	Phosphatidylinositol signaling system	27/884	112/7206	0.000413391519325
ko05030	Cocaine addiction	20/884	73/7206	0.000417704531912
ko03013	RNA transport	7/884	166/7206	0.000682588051909
ko05166	HTLV-I infection	18/884	292/7206	0.000692643992813
ko04626	Plant-pathogen interaction	8/884	18/7206	0.000700311447622
ko04612	Antigen processing and presentation	1/884	77/7206	0.000741214848624
ko03008	Ribosome biogenesis in eukaryotes	1/884	79/7206	0.000765632528532
ko05161	Hepatitis B	8/884	173/7206	0.000910193333282
ko04514	Cell adhesion molecules (CAMs)	29/884	130/7206	0.00107334639946
ko05140	Leishmaniasis	1/884	75/7206	0.00111557353345
ko05169	Epstein-Barr virus infection	11/884	206/7206	0.00112487122463
ko04110	Cell cycle	6/884	145/7206	0.00122254855001
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/884	79/7206	0.00142560835931
ko04964	Proximal tubule bicarbonate reclamation	10/884	29/7206	0.00163588470017
ko00010	Glycolysis / Gluconeogenesis	19/884	74/7206	0.00183960003914
ko04014	Ras signaling pathway	52/884	279/7206	0.00198941672857
ko04120	Ubiquitin mediated proteolysis	6/884	138/7206	0.00232743835258
ko04064	NF-kappa B signaling pathway	3/884	96/7206	0.00268989778557
ko04150	mTOR signaling pathway	10/884	184/7206	0.00283804212483
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/884	14/7206	0.00420231945805
ko04621	NOD-like receptor signaling pathway	8/884	157/7206	0.00426108412071
ko04930	Type II diabetes mellitus	14/884	54/7206	0.0053739549249
ko04360	Axon guidance	43/884	233/7206	0.00581652164703
ko04141	Protein processing in endoplasmic reticulum	11/884	184/7206	0.0060623060905
ko05010	Alzheimer's disease	38/884	202/7206	0.00626806306722
ko04657	IL-17 signaling pathway	3/884	87/7206	0.00774739712381
ko05215	Prostate cancer	5/884	111/7206	0.00822994809043
ko05200	Pathways in cancer	42/884	492/7206	0.00828876359795
ko05230	Central carbon metabolism in cancer	18/884	81/7206	0.00997797566456
ko04214	Apoptosis - fly	2/884	72/7206	0.0100946501356
ko04550	Signaling pathways regulating pluripotency of stem cells	10/884	165/7206	0.011310016931
ko00240	Pyrimidine metabolism	5/884	110/7206	0.0117147112641
ko00520	Amino sugar and nucleotide sugar metabolism	1/884	55/7206	0.0117880956428
ko00480	Glutathione metabolism	1/884	55/7206	0.0117880956428
ko00562	Inositol phosphate metabolism	19/884	89/7206	0.0137437820172
ko04371	Apelin signaling pathway	33/884	177/7206	0.014145158072
ko04072	Phospholipase D signaling pathway	36/884	197/7206	0.0147614338177
ko04611	Platelet activation	10/884	163/7206	0.0149885065707
ko04610	Complement and coagulation cascades	3/884	79/7206	0.0152886596133
ko04750	Inflammatory mediator regulation of TRP channels	24/884	122/7206	0.0171993958334
ko01230	Biosynthesis of amino acids	18/884	85/7206	0.0184957574856
ko04972	Pancreatic secretion	22/884	111/7206	0.0192702967134
ko04924	Renin secretion	18/884	86/7206	0.0196992629179
ko04210	Apoptosis	12/884	180/7206	0.0206060283863
ko01524	Platinum drug resistance	3/884	76/7206	0.0214523222082
ko05222	Small cell lung cancer	4/884	89/7206	0.0216691431766
ko05219	Bladder cancer	1/884	48/7206	0.0254484369934
ko00362	Benzoate degradation	3/884	6/7206	0.0276393955131
ko04960	Aldosterone-regulated sodium reabsorption	10/884	41/7206	0.0280632623677
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/884	59/7206	0.0282132365307
ko01200	Carbon metabolism	24/884	128/7206	0.0293095377433
ko04540	Gap junction	24/884	128/7206	0.0293095377433
ko04330	Notch signaling pathway	2/884	62/7206	0.0297539371418
ko05410	Hypertrophic cardiomyopathy (HCM)	20/884	100/7206	0.0297718655506
ko00680	Methane metabolism	9/884	34/7206	0.0299969101186
ko04668	TNF signaling pathway	7/884	120/7206	0.0337715476202
ko03022	Basal transcription factors	1/884	44/7206	0.037213392569
ko03420	Nucleotide excision repair	1/884	46/7206	0.0384894122619
ko05321	Inflammatory bowel disease (IBD)	2/884	56/7206	0.0411079198266
ko04914	Progesterone-mediated oocyte maturation	6/884	104/7206	0.0483858667852