ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 11/267 20/7206 1.84205696067e-11 ko04060 Cytokine-cytokine receptor interaction 24/267 191/7206 1.24003011141e-07 ko03320 PPAR signaling pathway 13/267 69/7206 1.11711802379e-06 ko04146 Peroxisome 13/267 89/7206 2.09292207642e-05 ko00071 Fatty acid degradation 9/267 45/7206 3.15669782862e-05 ko00983 Drug metabolism - other enzymes 8/267 42/7206 0.000126120019312 ko00830 Retinol metabolism 8/267 42/7206 0.000126120019312 ko04610 Complement and coagulation cascades 11/267 79/7206 0.000141567080182 ko00350 Tyrosine metabolism 7/267 33/7206 0.000165397888218 ko00643 Styrene degradation 3/267 4/7206 0.000195745389211 ko05144 Malaria 8/267 45/7206 0.000209167292133 ko05150 Staphylococcus aureus infection 7/267 36/7206 0.000293849992266 ko04620 Toll-like receptor signaling pathway 12/267 100/7206 0.000299671467108 ko04630 Jak-STAT signaling pathway 14/267 132/7206 0.000354948130141 ko00380 Tryptophan metabolism 8/267 50/7206 0.000443786388691 ko00140 Steroid hormone biosynthesis 7/267 41/7206 0.000675529171575 ko05340 Primary immunodeficiency 6/267 30/7206 0.000685633926238 ko04974 Protein digestion and absorption 11/267 96/7206 0.000791676509919 ko04064 NF-kappa B signaling pathway 11/267 96/7206 0.000791676509919 ko00100 Steroid biosynthesis 5/267 21/7206 0.000839921940249 ko01212 Fatty acid metabolism 8/267 60/7206 0.0015362360981 ko05323 Rheumatoid arthritis 10/267 89/7206 0.00158281368585 ko05204 Chemical carcinogenesis 7/267 48/7206 0.00177384830949 ko05034 Alcoholism 1/267 238/7206 0.00239854575554 ko04611 Platelet activation 14/267 163/7206 0.00280981620999 ko00360 Phenylalanine metabolism 4/267 17/7206 0.00299366461722 ko04380 Osteoclast differentiation 12/267 134/7206 0.00394147823611 ko00592 alpha-Linolenic acid metabolism 4/267 19/7206 0.00459915746138 ko05133 Pertussis 9/267 87/7206 0.00470892838238 ko05164 Influenza A 14/267 167/7206 0.00520173838359 ko05134 Legionellosis 8/267 74/7206 0.00579799884276 ko05145 Toxoplasmosis 11/267 126/7206 0.00686736285448 ko04080 Neuroactive ligand-receptor interaction 6/267 423/7206 0.00738413857289 ko00640 Propanoate metabolism 5/267 34/7206 0.00775506779396 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/267 4/7206 0.00781057113384 ko00053 Ascorbate and aldarate metabolism 4/267 22/7206 0.00795491423682 ko00410 beta-Alanine metabolism 5/267 35/7206 0.00878013471201 ko00500 Starch and sucrose metabolism 5/267 35/7206 0.00878013471201 ko04650 Natural killer cell mediated cytotoxicity 9/267 97/7206 0.00953059033179 ko05132 Salmonella infection 9/267 98/7206 0.0101649611212 ko05131 Shigellosis 8/267 82/7206 0.0106463842511 ko04672 Intestinal immune network for IgA production 5/267 37/7206 0.0111037759856 ko00982 Drug metabolism - cytochrome P450 5/267 37/7206 0.0111037759856 ko00281 Geraniol degradation 2/267 5/7206 0.012700328256 ko04142 Lysosome 12/267 151/7206 0.0132105677487 ko04014 Ras signaling pathway 3/267 279/7206 0.0139493335071 ko00040 Pentose and glucuronate interconversions 4/267 26/7206 0.0144810956867 ko05206 MicroRNAs in cancer 1/267 177/7206 0.0150767900983 ko04310 Wnt signaling pathway 1/267 181/7206 0.015173166058 ko00980 Metabolism of xenobiotics by cytochrome P450 5/267 40/7206 0.015324393671 ko04662 B cell receptor signaling pathway 8/267 88/7206 0.0158927985464 ko05321 Inflammatory bowel disease (IBD) 6/267 56/7206 0.016822699689 ko00362 Benzoate degradation 2/267 6/7206 0.0185875931149 ko04020 Calcium signaling pathway 3/267 265/7206 0.0190639501497 ko05140 Leishmaniasis 7/267 75/7206 0.0205692066153 ko04972 Pancreatic secretion 9/267 111/7206 0.0215910067762 ko05224 Breast cancer 1/267 174/7206 0.0224951505424 ko04723 Retrograde endocannabinoid signaling 1/267 175/7206 0.0227212976801 ko05310 Asthma 3/267 17/7206 0.0232707412657 ko04612 Antigen processing and presentation 7/267 77/7206 0.0234256014253 ko04660 T cell receptor signaling pathway 10/267 124/7206 0.0253241695438 ko05016 Huntington's disease 2/267 215/7206 0.025524316872 ko04622 RIG-I-like receptor signaling pathway 6/267 62/7206 0.0265352750029 ko04614 Renin-angiotensin system 3/267 18/7206 0.0271772305077 ko05142 Chagas disease (American trypanosomiasis) 10/267 130/7206 0.0292041743092 ko00260 Glycine, serine and threonine metabolism 5/267 48/7206 0.0314421007739 ko04550 Signaling pathways regulating pluripotency of stem cells 1/267 165/7206 0.0329907096835 ko00740 Riboflavin metabolism 2/267 8/7206 0.0330388701926 ko00860 Porphyrin and chlorophyll metabolism 4/267 34/7206 0.0357086036742 ko00401 Novobiocin biosynthesis 1/267 1/7206 0.0370524562864 ko04975 Fat digestion and absorption 4/267 35/7206 0.0391832448304 ko00627 Aminobenzoate degradation 2/267 9/7206 0.0414560876599 ko00590 Arachidonic acid metabolism 5/267 52/7206 0.0424092914178 ko05162 Measles 9/267 120/7206 0.0439794158695 ko04668 TNF signaling pathway 9/267 120/7206 0.0439794158695 ko05200 Pathways in cancer 10/267 492/7206 0.0465419445892 ko05012 Parkinson's disease 1/267 155/7206 0.0477901161328 ko00280 Valine, leucine and isoleucine degradation 5/267 54/7206 0.0486571707975 ko05203 Viral carcinogenesis 4/267 277/7206 0.0488440540894 ko04621 NOD-like receptor signaling pathway 11/267 157/7206 0.0490072323195