ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	91/643	423/7206	3.34255199057e-16
ko04260	Cardiac muscle contraction	38/643	98/7206	5.9198154774e-16
ko04261	Adrenergic signaling in cardiomyocytes	55/643	205/7206	2.39411621442e-14
ko05033	Nicotine addiction	25/643	56/7206	1.4429570442e-12
ko04713	Circadian entrainment	38/643	136/7206	7.64575527286e-11
ko04724	Glutamatergic synapse	39/643	152/7206	6.90274447925e-10
ko04911	Insulin secretion	33/643	117/7206	1.06456949298e-09
ko05410	Hypertrophic cardiomyopathy (HCM)	30/643	100/7206	1.21793735684e-09
ko04020	Calcium signaling pathway	54/643	265/7206	4.10009881666e-09
ko04728	Dopaminergic synapse	41/643	185/7206	2.63244211758e-08
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/643	79/7206	4.31004907358e-08
ko05414	Dilated cardiomyopathy	29/643	112/7206	8.92097415231e-08
ko04024	cAMP signaling pathway	52/643	279/7206	2.51446578772e-07
ko04921	Oxytocin signaling pathway	42/643	209/7206	3.82472080997e-07
ko04974	Protein digestion and absorption	25/643	96/7206	6.17773757381e-07
ko04721	Synaptic vesicle cycle	22/643	80/7206	1.07309877821e-06
ko04723	Retrograde endocannabinoid signaling	36/643	175/7206	1.35873025262e-06
ko04964	Proximal tubule bicarbonate reclamation	12/643	29/7206	2.87963793055e-06
ko05031	Amphetamine addiction	23/643	91/7206	3.04217741218e-06
ko04512	ECM-receptor interaction	21/643	79/7206	3.42964753121e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	20/643	74/7206	4.43740484491e-06
ko04970	Salivary secretion	23/643	95/7206	6.6768584638e-06
ko04022	cGMP-PKG signaling pathway	40/643	216/7206	7.89203064639e-06
ko04727	GABAergic synapse	25/643	110/7206	8.95277373425e-06
ko05168	Herpes simplex infection	2/643	182/7206	9.47821162368e-06
ko04725	Cholinergic synapse	31/643	160/7206	2.96224936603e-05
ko04971	Gastric acid secretion	22/643	98/7206	3.76388956965e-05
ko03040	Spliceosome	1/643	145/7206	4.2020383763e-05
ko05164	Influenza A	2/643	167/7206	4.51017626188e-05
ko04060	Cytokine-cytokine receptor interaction	3/643	191/7206	4.5525966629e-05
ko04978	Mineral absorption	12/643	40/7206	0.00012369307967
ko05322	Systemic lupus erythematosus	2/643	151/7206	0.000136314873789
ko00020	Citrate cycle (TCA cycle)	11/643	35/7206	0.000148848813816
ko01200	Carbon metabolism	25/643	128/7206	0.00021031471464
ko00010	Glycolysis / Gluconeogenesis	17/643	74/7206	0.000210427972875
ko05203	Viral carcinogenesis	9/643	277/7206	0.000229045590334
ko04514	Cell adhesion molecules (CAMs)	25/643	130/7206	0.000236343143844
ko05032	Morphine addiction	22/643	110/7206	0.000262566627514
ko04140	Autophagy - animal	3/643	164/7206	0.000264154878508
ko04150	mTOR signaling pathway	4/643	184/7206	0.000324693055503
ko04120	Ubiquitin mediated proteolysis	2/643	138/7206	0.000420017734937
ko04976	Bile secretion	17/643	80/7206	0.000560394858251
ko05030	Cocaine addiction	16/643	73/7206	0.000563466646318
ko04010	MAPK signaling pathway	47/643	321/7206	0.000596727152703
ko05010	Alzheimer's disease	33/643	202/7206	0.000605520313556
ko04742	Taste transduction	14/643	61/7206	0.000757282157432
ko04726	Serotonergic synapse	24/643	137/7206	0.00120661538515
ko03013	RNA transport	4/643	166/7206	0.00129381973233
ko01230	Biosynthesis of amino acids	17/643	85/7206	0.00149419294032
ko05166	HTLV-I infection	12/643	292/7206	0.00218324325321
ko04922	Glucagon signaling pathway	22/643	128/7206	0.00249760277115
ko04621	NOD-like receptor signaling pathway	4/643	157/7206	0.00254899181795
ko05161	Hepatitis B	5/643	173/7206	0.00265148060669
ko05416	Viral myocarditis	12/643	55/7206	0.00280376156668
ko04142	Lysosome	4/643	151/7206	0.00348099913382
ko04720	Long-term potentiation	18/643	99/7206	0.00357032467391
ko04510	Focal adhesion	35/643	240/7206	0.00366085676653
ko00240	Pyrimidine metabolism	2/643	110/7206	0.00379275650578
ko00220	Arginine biosynthesis	7/643	24/7206	0.00391159377953
ko04730	Long-term depression	15/643	78/7206	0.00395712053613
ko04146	Peroxisome	1/643	89/7206	0.00423467048451
ko04360	Axon guidance	34/643	233/7206	0.00464828851619
ko04740	Olfactory transduction	15/643	80/7206	0.00478852726803
ko04550	Signaling pathways regulating pluripotency of stem cells	5/643	165/7206	0.00512660607232
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/643	59/7206	0.00514837594096
ko00250	Alanine, aspartate and glutamate metabolism	9/643	38/7206	0.00521574725221
ko05012	Parkinson's disease	24/643	155/7206	0.00646464952974
ko00350	Tyrosine metabolism	8/643	33/7206	0.0071533549037
ko00710	Carbon fixation in photosynthetic organisms	7/643	27/7206	0.0079337820966
ko04914	Progesterone-mediated oocyte maturation	2/643	104/7206	0.00809229775254
ko04960	Aldosterone-regulated sodium reabsorption	9/643	41/7206	0.00881300237854
ko05162	Measles	3/643	120/7206	0.00884259732406
ko03008	Ribosome biogenesis in eukaryotes	1/643	79/7206	0.00901078470811
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/643	135/7206	0.00917845712027
ko04137	Mitophagy - animal	1/643	82/7206	0.00949623028401
ko04973	Carbohydrate digestion and absorption	9/643	42/7206	0.0103543934432
ko04062	Chemokine signaling pathway	8/643	201/7206	0.0113276285904
ko04924	Renin secretion	15/643	86/7206	0.0113928310389
ko05140	Leishmaniasis	1/643	75/7206	0.0132100652419
ko04745	Phototransduction - fly	8/643	38/7206	0.0169740909474
ko04110	Cell cycle	5/643	145/7206	0.0173669863385
ko00620	Pyruvate metabolism	9/643	46/7206	0.0185988076731
ko00030	Pentose phosphate pathway	7/643	32/7206	0.0203793395701
ko04371	Apelin signaling pathway	25/643	177/7206	0.0220102618013
ko04657	IL-17 signaling pathway	2/643	87/7206	0.0223889961721
ko01522	Endocrine resistance	4/643	124/7206	0.024350725989
ko04972	Pancreatic secretion	17/643	111/7206	0.027060748267
ko01210	2-Oxocarboxylic acid metabolism	5/643	20/7206	0.0279032178814
ko00680	Methane metabolism	7/643	34/7206	0.0279064357205
ko04630	Jak-STAT signaling pathway	5/643	132/7206	0.0310467573413
ko00500	Starch and sucrose metabolism	7/643	35/7206	0.0322955125699
ko04620	Toll-like receptor signaling pathway	3/643	100/7206	0.0328234396988
ko04210	Apoptosis	8/643	180/7206	0.0330158721727
ko04668	TNF signaling pathway	4/643	120/7206	0.0335509038291
ko04350	TGF-beta signaling pathway	3/643	103/7206	0.0340736378676
ko05169	Epstein-Barr virus infection	10/643	206/7206	0.0347898008359
ko00600	Sphingolipid metabolism	1/643	63/7206	0.0417521309245
ko04640	Hematopoietic cell lineage	1/643	64/7206	0.0427756714864
ko05215	Prostate cancer	4/643	111/7206	0.043831517563
ko04151	PI3K-Akt signaling pathway	46/643	390/7206	0.0444674071722
ko04664	Fc epsilon RI signaling pathway	2/643	77/7206	0.0446337204954
ko04658	Th1 and Th2 cell differentiation	3/643	96/7206	0.0454740121018
ko04138	Autophagy - yeast	2/643	81/7206	0.0463257949527
ko04141	Protein processing in endoplasmic reticulum	9/643	184/7206	0.0495020624392