ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	118/896	423/7206	7.99965704358e-19
ko05033	Nicotine addiction	29/896	56/7206	9.59707068593e-13
ko04020	Calcium signaling pathway	73/896	265/7206	1.40307001468e-11
ko04727	GABAergic synapse	40/896	110/7206	7.68777578479e-11
ko05032	Morphine addiction	39/896	110/7206	3.19233869398e-10
ko04713	Circadian entrainment	44/896	136/7206	6.97551348771e-10
ko04724	Glutamatergic synapse	47/896	152/7206	1.00135630774e-09
ko04721	Synaptic vesicle cycle	30/896	80/7206	8.02508256689e-09
ko04728	Dopaminergic synapse	50/896	185/7206	4.99068066393e-08
ko04070	Phosphatidylinositol signaling system	34/896	112/7206	3.4725853018e-07
ko04911	Insulin secretion	35/896	117/7206	5.03808670244e-07
ko04024	cAMP signaling pathway	64/896	279/7206	6.46823299578e-07
ko04022	cGMP-PKG signaling pathway	53/896	216/7206	8.83300717955e-07
ko03010	Ribosome	1/896	129/7206	1.12765811212e-06
ko04970	Salivary secretion	29/896	95/7206	2.22529697479e-06
ko04726	Serotonergic synapse	37/896	137/7206	2.80383725773e-06
ko04921	Oxytocin signaling pathway	50/896	209/7206	3.23577427617e-06
ko04723	Retrograde endocannabinoid signaling	44/896	175/7206	3.67506711581e-06
ko03013	RNA transport	4/896	166/7206	6.83959032862e-06
ko04725	Cholinergic synapse	40/896	160/7206	9.29630304399e-06
ko04261	Adrenergic signaling in cardiomyocytes	48/896	205/7206	1.24375517385e-05
ko05031	Amphetamine addiction	27/896	91/7206	1.41919255525e-05
ko04514	Cell adhesion molecules (CAMs)	34/896	130/7206	1.92416869174e-05
ko04710	Circadian rhythm	16/896	43/7206	2.87419204195e-05
ko05322	Systemic lupus erythematosus	4/896	151/7206	2.92621493274e-05
ko04014	Ras signaling pathway	58/896	279/7206	5.88982474901e-05
ko03040	Spliceosome	4/896	145/7206	6.09980504821e-05
ko04925	Aldosterone synthesis and secretion	28/896	105/7206	6.70294923402e-05
ko04720	Long-term potentiation	27/896	99/7206	7.50576319152e-05
ko04745	Phototransduction - fly	13/896	38/7206	0.000423267057526
ko04730	Long-term depression	21/896	78/7206	0.000423308894951
ko05203	Viral carcinogenesis	17/896	277/7206	0.000756906778737
ko05168	Herpes simplex infection	9/896	182/7206	0.000886465916385
ko04072	Phospholipase D signaling pathway	41/896	197/7206	0.00090135343005
ko04742	Taste transduction	17/896	61/7206	0.00119379921074
ko00562	Inositol phosphate metabolism	22/896	89/7206	0.00167528507267
ko04010	MAPK signaling pathway	59/896	321/7206	0.00174050397501
ko04015	Rap1 signaling pathway	52/896	278/7206	0.00211719892298
ko04371	Apelin signaling pathway	36/896	177/7206	0.0024937297454
ko04922	Glucagon signaling pathway	28/896	128/7206	0.00258362620913
ko04930	Type II diabetes mellitus	15/896	54/7206	0.00258983021934
ko04270	Vascular smooth muscle contraction	32/896	154/7206	0.00284495253861
ko04971	Gastric acid secretion	23/896	98/7206	0.00284805864166
ko04966	Collecting duct acid secretion	9/896	26/7206	0.00296664628668
ko04960	Aldosterone-regulated sodium reabsorption	12/896	41/7206	0.00320340885814
ko04744	Phototransduction	11/896	36/7206	0.00325022974268
ko04626	Plant-pathogen interaction	7/896	18/7206	0.0041249235026
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/896	14/7206	0.00450076370317
ko04924	Renin secretion	20/896	86/7206	0.00460668797442
ko04750	Inflammatory mediator regulation of TRP channels	26/896	122/7206	0.00516144946769
ko05230	Central carbon metabolism in cancer	19/896	81/7206	0.00575247713005
ko04120	Ubiquitin mediated proteolysis	7/896	138/7206	0.00579587004744
ko04068	FoxO signaling pathway	33/896	167/7206	0.00602819225571
ko04360	Axon guidance	43/896	233/7206	0.00636807614283
ko04110	Cell cycle	8/896	145/7206	0.00739721293192
ko04657	IL-17 signaling pathway	3/896	87/7206	0.00788117035302
ko05016	Huntington's disease	15/896	215/7206	0.0115308219313
ko03050	Proteasome	1/896	54/7206	0.0116653774803
ko04141	Protein processing in endoplasmic reticulum	12/896	184/7206	0.0122739177605
ko04711	Circadian rhythm - fly	5/896	13/7206	0.0160304380912
ko04540	Gap junction	25/896	128/7206	0.0205845922472
ko00010	Glycolysis / Gluconeogenesis	16/896	74/7206	0.0212828401168
ko04964	Proximal tubule bicarbonate reclamation	8/896	29/7206	0.0217080841337
ko05130	Pathogenic Escherichia coli infection	3/896	77/7206	0.0220235344005
ko04137	Mitophagy - animal	17/896	82/7206	0.0281656908491
ko00362	Benzoate degradation	3/896	6/7206	0.0286647945124
ko04214	Apoptosis - fly	3/896	72/7206	0.0299064581587
ko05110	Vibrio cholerae infection	14/896	63/7206	0.0317534516409
ko03022	Basal transcription factors	1/896	44/7206	0.0371746292155
ko04066	HIF-1 signaling pathway	23/896	123/7206	0.0386475193863
ko03420	Nucleotide excision repair	1/896	46/7206	0.0391957206691
ko05214	Glioma	16/896	79/7206	0.0398389262102
ko04919	Thyroid hormone signaling pathway	26/896	143/7206	0.0403959098015
ko05169	Epstein-Barr virus infection	16/896	206/7206	0.0411545104583
ko05164	Influenza A	12/896	167/7206	0.0425484257153
ko05161	Hepatitis B	13/896	173/7206	0.04708445736
ko05030	Cocaine addiction	15/896	73/7206	0.0473541019765
ko05014	Amyotrophic lateral sclerosis (ALS)	15/896	74/7206	0.0497997300036