ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	73/806	152/7206	1.2026854418e-30
ko04080	Neuroactive ligand-receptor interaction	130/806	423/7206	1.17709543935e-29
ko05033	Nicotine addiction	42/806	56/7206	5.21735067516e-29
ko04727	GABAergic synapse	56/806	110/7206	2.48545750934e-25
ko05032	Morphine addiction	56/806	110/7206	2.48545750934e-25
ko04713	Circadian entrainment	59/806	136/7206	4.42529917866e-22
ko04723	Retrograde endocannabinoid signaling	65/806	175/7206	7.71014039036e-20
ko04728	Dopaminergic synapse	67/806	185/7206	9.97798303419e-20
ko04744	Phototransduction	27/806	36/7206	4.84246877042e-19
ko04024	cAMP signaling pathway	78/806	279/7206	2.70756226488e-15
ko04725	Cholinergic synapse	55/806	160/7206	3.10422201332e-15
ko04726	Serotonergic synapse	47/806	137/7206	3.74209474043e-13
ko04721	Synaptic vesicle cycle	33/806	80/7206	3.94151312099e-12
ko04020	Calcium signaling pathway	69/806	265/7206	5.43222520265e-12
ko04742	Taste transduction	28/806	61/7206	7.5445831747e-12
ko04921	Oxytocin signaling pathway	57/806	209/7206	6.63058400154e-11
ko04911	Insulin secretion	39/806	117/7206	1.07291274265e-10
ko05031	Amphetamine addiction	33/806	91/7206	2.4279682057e-10
ko04261	Adrenergic signaling in cardiomyocytes	54/806	205/7206	7.4947085604e-10
ko05030	Cocaine addiction	27/806	73/7206	6.45449570612e-09
ko04720	Long-term potentiation	32/806	99/7206	1.22203174896e-08
ko05203	Viral carcinogenesis	7/806	277/7206	9.07374850931e-08
ko04970	Salivary secretion	29/806	95/7206	2.39368908343e-07
ko04060	Cytokine-cytokine receptor interaction	3/806	191/7206	5.52226475324e-07
ko03040	Spliceosome	1/806	145/7206	8.49788489437e-07
ko04010	MAPK signaling pathway	64/806	321/7206	2.86505475645e-06
ko04740	Olfactory transduction	24/806	80/7206	3.68032077928e-06
ko05164	Influenza A	3/806	167/7206	8.43289481033e-06
ko04260	Cardiac muscle contraction	26/806	98/7206	2.56976669202e-05
ko04925	Aldosterone synthesis and secretion	27/806	105/7206	2.59494237658e-05
ko04070	Phosphatidylinositol signaling system	28/806	112/7206	2.93642246923e-05
ko05205	Proteoglycans in cancer	11/806	271/7206	3.13641922164e-05
ko04022	cGMP-PKG signaling pathway	44/806	216/7206	6.37850050452e-05
ko05169	Epstein-Barr virus infection	7/806	206/7206	7.06372036712e-05
ko04730	Long-term depression	21/806	78/7206	8.80046113529e-05
ko03013	RNA transport	5/806	166/7206	0.000160349869181
ko05162	Measles	2/806	120/7206	0.00018202301996
ko04972	Pancreatic secretion	26/806	111/7206	0.000197003154525
ko05322	Systemic lupus erythematosus	4/806	151/7206	0.000200277133046
ko04110	Cell cycle	4/806	145/7206	0.000279184876737
ko04072	Phospholipase D signaling pathway	39/806	197/7206	0.000324714852585
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/806	79/7206	0.000398888163339
ko04621	NOD-like receptor signaling pathway	5/806	157/7206	0.000453489141919
ko05168	Herpes simplex infection	7/806	182/7206	0.000505871126108
ko05014	Amyotrophic lateral sclerosis (ALS)	19/806	74/7206	0.000514689093673
ko04514	Cell adhesion molecules (CAMs)	28/806	130/7206	0.000594440076104
ko04745	Phototransduction - fly	12/806	38/7206	0.000604419677503
ko04964	Proximal tubule bicarbonate reclamation	10/806	29/7206	0.000793164693474
ko05166	HTLV-I infection	16/806	292/7206	0.00085087354652
ko04971	Gastric acid secretion	22/806	98/7206	0.00108885386203
ko04141	Protein processing in endoplasmic reticulum	8/806	184/7206	0.00130666170049
ko04924	Renin secretion	20/806	86/7206	0.00144599692382
ko05034	Alcoholism	43/806	238/7206	0.0015471958612
ko04610	Complement and coagulation cascades	1/806	79/7206	0.00177742225922
ko03008	Ribosome biogenesis in eukaryotes	1/806	79/7206	0.00177742225922
ko00562	Inositol phosphate metabolism	20/806	89/7206	0.00191325907157
ko04510	Focal adhesion	13/806	240/7206	0.0024054289832
ko04810	Regulation of actin cytoskeleton	15/806	264/7206	0.0026748308907
ko05161	Hepatitis B	8/806	173/7206	0.00322382420914
ko04014	Ras signaling pathway	47/806	279/7206	0.00352642277936
ko05414	Dilated cardiomyopathy	23/806	112/7206	0.0035689363856
ko00230	Purine metabolism	35/806	194/7206	0.00369219962333
ko04350	TGF-beta signaling pathway	3/806	103/7206	0.00405671130264
ko04630	Jak-STAT signaling pathway	5/806	132/7206	0.00472413596192
ko04966	Collecting duct acid secretion	8/806	26/7206	0.00586753725425
ko04120	Ubiquitin mediated proteolysis	6/806	138/7206	0.00622153801918
ko04710	Circadian rhythm	11/806	43/7206	0.00636306642072
ko04064	NF-kappa B signaling pathway	3/806	96/7206	0.00816407114236
ko05130	Pathogenic Escherichia coli infection	2/806	77/7206	0.0102393294563
ko04330	Notch signaling pathway	1/806	62/7206	0.0128825260961
ko00910	Nitrogen metabolism	6/806	19/7206	0.0144894609983
ko05140	Leishmaniasis	2/806	75/7206	0.0149745874423
ko04930	Type II diabetes mellitus	12/806	54/7206	0.0159685115722
ko04550	Signaling pathways regulating pluripotency of stem cells	9/806	165/7206	0.0168156840112
ko05416	Viral myocarditis	1/806	55/7206	0.0178984427046
ko04976	Bile secretion	16/806	80/7206	0.0188356004866
ko04371	Apelin signaling pathway	30/806	177/7206	0.0208529810606
ko03320	PPAR signaling pathway	2/806	69/7206	0.0209382814453
ko05145	Toxoplasmosis	6/806	126/7206	0.0211979239802
ko04540	Gap junction	23/806	128/7206	0.0222252594012
ko05410	Hypertrophic cardiomyopathy (HCM)	19/806	100/7206	0.0234275712843
ko04915	Estrogen signaling pathway	23/806	131/7206	0.0247802927649
ko00590	Arachidonic acid metabolism	1/806	52/7206	0.0261924566976
ko05217	Basal cell carcinoma	2/806	68/7206	0.0306997880661
ko05131	Shigellosis	3/806	82/7206	0.0319884083356
ko05202	Transcriptional misregulation in cancer	12/806	188/7206	0.034139473697
ko05231	Choline metabolism in cancer	23/806	134/7206	0.0365159885016
ko05224	Breast cancer	11/806	174/7206	0.0380555216429
ko04978	Mineral absorption	9/806	40/7206	0.0381372281243
ko04062	Chemokine signaling pathway	32/806	201/7206	0.0400503737454
ko04146	Peroxisome	4/806	89/7206	0.0415881646248
ko05222	Small cell lung cancer	4/806	89/7206	0.0415881646248
ko04640	Hematopoietic cell lineage	2/806	64/7206	0.0432412623086
ko04150	mTOR signaling pathway	12/806	184/7206	0.0432507744522
ko04973	Carbohydrate digestion and absorption	9/806	42/7206	0.0461940113883
ko05215	Prostate cancer	6/806	111/7206	0.0486821011571