ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 17/122 152/7206 5.07789346045e-10 ko04713 Circadian entrainment 15/122 136/7206 6.98347150821e-09 ko04727 GABAergic synapse 12/122 110/7206 2.78852213285e-07 ko05033 Nicotine addiction 9/122 56/7206 3.29634302746e-07 ko04728 Dopaminergic synapse 15/122 185/7206 4.37885034511e-07 ko04911 Insulin secretion 12/122 117/7206 5.49870765646e-07 ko04514 Cell adhesion molecules (CAMs) 12/122 130/7206 1.71767607069e-06 ko04721 Synaptic vesicle cycle 9/122 80/7206 7.1750169478e-06 ko04725 Cholinergic synapse 12/122 160/7206 1.49556252482e-05 ko04024 cAMP signaling pathway 16/122 279/7206 1.68416535326e-05 ko04726 Serotonergic synapse 11/122 137/7206 1.82191357921e-05 ko05031 Amphetamine addiction 9/122 91/7206 2.07442552308e-05 ko04723 Retrograde endocannabinoid signaling 12/122 175/7206 3.67214266616e-05 ko04261 Adrenergic signaling in cardiomyocytes 13/122 205/7206 3.91394698791e-05 ko05032 Morphine addiction 9/122 110/7206 9.38659847863e-05 ko04970 Salivary secretion 8/122 95/7206 0.000190496278166 ko05014 Amyotrophic lateral sclerosis (ALS) 7/122 74/7206 0.000236037937173 ko04720 Long-term potentiation 8/122 99/7206 0.000253614773472 ko04972 Pancreatic secretion 8/122 111/7206 0.000552473138958 ko04260 Cardiac muscle contraction 7/122 98/7206 0.00129886008743 ko04964 Proximal tubule bicarbonate reclamation 4/122 29/7206 0.00133865795794 ko04360 Axon guidance 11/122 233/7206 0.00189775168811 ko05034 Alcoholism 11/122 238/7206 0.00224384849401 ko04978 Mineral absorption 4/122 40/7206 0.00446418340312 ko04960 Aldosterone-regulated sodium reabsorption 4/122 41/7206 0.00488305879077 ko04973 Carbohydrate digestion and absorption 4/122 42/7206 0.00532756023825 ko04971 Gastric acid secretion 6/122 98/7206 0.00617210088971 ko04014 Ras signaling pathway 11/122 279/7206 0.00745423743001 ko05030 Cocaine addiction 5/122 73/7206 0.00769297131591 ko04921 Oxytocin signaling pathway 9/122 209/7206 0.00879874003931 ko04966 Collecting duct acid secretion 3/122 26/7206 0.00926582827294 ko04022 cGMP-PKG signaling pathway 9/122 216/7206 0.0107894229058 ko04924 Renin secretion 5/122 86/7206 0.0150042386785 ko05167 Kaposi's sarcoma-associated herpesvirus infection 8/122 191/7206 0.0154801697442 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/122 1/7206 0.0169303358313 ko04961 Endocrine and other factor-regulated calcium reabsorption 4/122 59/7206 0.0173970431171 ko05120 Epithelial cell signaling in Helicobacter pylori infection 5/122 92/7206 0.0195674972546 ko04145 Phagosome 7/122 162/7206 0.0197543317655 ko04062 Chemokine signaling pathway 8/122 201/7206 0.0204190920222 ko05110 Vibrio cholerae infection 4/122 63/7206 0.0216305089545 ko04010 MAPK signaling pathway 11/122 321/7206 0.0234062513458 ko02024 Quorum sensing 2/122 15/7206 0.0258498927687 ko04745 Phototransduction - fly 3/122 38/7206 0.0259713312683 ko04080 Neuroactive ligand-receptor interaction 13/122 423/7206 0.0313146365839 ko04626 Plant-pathogen interaction 2/122 18/7206 0.0364487622635 ko04730 Long-term depression 4/122 78/7206 0.0427787202635 ko04020 Calcium signaling pathway 9/122 265/7206 0.0452835727985 ko04976 Bile secretion 4/122 80/7206 0.046243249005