ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 35/258 79/7206 1.98875146309e-30 ko04974 Protein digestion and absorption 20/258 96/7206 1.08786515274e-10 ko00983 Drug metabolism - other enzymes 12/258 42/7206 1.46066724906e-08 ko04976 Bile secretion 15/258 80/7206 1.11801055529e-07 ko05150 Staphylococcus aureus infection 10/258 36/7206 3.24857363604e-07 ko04977 Vitamin digestion and absorption 8/258 22/7206 5.01210788522e-07 ko04614 Renin-angiotensin system 7/258 18/7206 1.57807098181e-06 ko04975 Fat digestion and absorption 9/258 35/7206 2.62332076993e-06 ko02010 ABC transporters 9/258 39/7206 6.94309234476e-06 ko05204 Chemical carcinogenesis 9/258 48/7206 4.14275685187e-05 ko00380 Tryptophan metabolism 9/258 50/7206 5.81292213454e-05 ko04973 Carbohydrate digestion and absorption 8/258 42/7206 9.92556226997e-05 ko04972 Pancreatic secretion 13/258 111/7206 0.000153581850625 ko00500 Starch and sucrose metabolism 7/258 35/7206 0.000197734003883 ko00232 Caffeine metabolism 3/258 5/7206 0.000430067970868 ko00980 Metabolism of xenobiotics by cytochrome P450 7/258 40/7206 0.000470475266781 ko04978 Mineral absorption 7/258 40/7206 0.000470475266781 ko04950 Maturity onset diabetes of the young 6/258 29/7206 0.00047137406252 ko05166 HTLV-I infection 1/258 292/7206 0.00052912743531 ko00140 Steroid hormone biosynthesis 7/258 41/7206 0.000550273831193 ko00830 Retinol metabolism 7/258 42/7206 0.000640477472886 ko00591 Linoleic acid metabolism 5/258 22/7206 0.000903235482562 ko05133 Pertussis 10/258 87/7206 0.00102414668558 ko00260 Glycine, serine and threonine metabolism 7/258 48/7206 0.00145593739418 ko00340 Histidine metabolism 5/258 25/7206 0.00166904890412 ko00982 Drug metabolism - cytochrome P450 6/258 37/7206 0.00181491562979 ko00630 Glyoxylate and dicarboxylate metabolism 6/258 38/7206 0.00209173436868 ko00520 Amino sugar and nucleotide sugar metabolism 7/258 55/7206 0.0032443319159 ko04360 Axon guidance 1/258 233/7206 0.00344055755436 ko05034 Alcoholism 1/258 238/7206 0.00361318951154 ko00120 Primary bile acid biosynthesis 4/258 20/7206 0.00494371531631 ko00350 Tyrosine metabolism 5/258 33/7206 0.00590535356679 ko00052 Galactose metabolism 5/258 33/7206 0.00590535356679 ko00100 Steroid biosynthesis 4/258 21/7206 0.00593782880237 ko04922 Glucagon signaling pathway 11/258 128/7206 0.00600356204657 ko00270 Cysteine and methionine metabolism 6/258 47/7206 0.0062223120936 ko00053 Ascorbate and aldarate metabolism 4/258 22/7206 0.00705662731789 ko00643 Styrene degradation 2/258 4/7206 0.00730435225662 ko00590 Arachidonic acid metabolism 6/258 52/7206 0.0101725222877 ko04144 Endocytosis 4/258 342/7206 0.0103199304658 ko03320 PPAR signaling pathway 7/258 69/7206 0.011304314582 ko05200 Pathways in cancer 8/258 492/7206 0.0116310430299 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/258 5/7206 0.0118872084473 ko00770 Pantothenate and CoA biosynthesis 3/258 14/7206 0.0123188820242 ko00040 Pentose and glucuronate interconversions 4/258 26/7206 0.0128961015396 ko00480 Glutathione metabolism 6/258 55/7206 0.0132563825184 ko05020 Prion diseases 5/258 40/7206 0.0133704054492 ko04141 Protein processing in endoplasmic reticulum 1/258 184/7206 0.0150885865752 ko04964 Proximal tubule bicarbonate reclamation 4/258 29/7206 0.0188470303178 ko04010 MAPK signaling pathway 4/258 321/7206 0.0195842683576 ko00360 Phenylalanine metabolism 3/258 17/7206 0.0212654270549 ko04913 Ovarian steroidogenesis 6/258 63/7206 0.0245538614353 ko04080 Neuroactive ligand-receptor interaction 7/258 423/7206 0.0294799228254 ko04550 Signaling pathways regulating pluripotency of stem cells 1/258 165/7206 0.0316195945207 ko00860 Porphyrin and chlorophyll metabolism 4/258 34/7206 0.0320446885158 ko04924 Renin secretion 7/258 86/7206 0.0338695381674 ko05169 Epstein-Barr virus infection 2/258 206/7206 0.0351320453134 ko00410 beta-Alanine metabolism 4/258 35/7206 0.035195980434 ko00401 Novobiocin biosynthesis 1/258 1/7206 0.0358034970858 ko04146 Peroxisome 7/258 89/7206 0.0397313271292 ko00250 Alanine, aspartate and glutamate metabolism 4/258 38/7206 0.0456912123342 ko00072 Synthesis and degradation of ketone bodies 2/258 10/7206 0.0475347026288 ko04725 Cholinergic synapse 1/258 160/7206 0.0476346418682 ko01200 Carbon metabolism 9/258 128/7206 0.0487310632246