ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 33/186 79/7206 1.45736942596e-32 ko04977 Vitamin digestion and absorption 9/186 22/7206 1.56173006461e-09 ko04975 Fat digestion and absorption 10/186 35/7206 1.08114758339e-08 ko05150 Staphylococcus aureus infection 10/186 36/7206 1.46374813559e-08 ko03320 PPAR signaling pathway 12/186 69/7206 1.49606840125e-07 ko04978 Mineral absorption 9/186 40/7206 5.74378366082e-07 ko00983 Drug metabolism - other enzymes 9/186 42/7206 8.9577343735e-07 ko04950 Maturity onset diabetes of the young 7/186 29/7206 6.57800050284e-06 ko00630 Glyoxylate and dicarboxylate metabolism 7/186 38/7206 4.36926771673e-05 ko04614 Renin-angiotensin system 5/186 18/7206 7.07760661343e-05 ko01200 Carbon metabolism 12/186 128/7206 0.000106629895259 ko04976 Bile secretion 9/186 80/7206 0.000200146901048 ko00260 Glycine, serine and threonine metabolism 7/186 48/7206 0.000204995814763 ko04146 Peroxisome 9/186 89/7206 0.000449458922096 ko00480 Glutathione metabolism 7/186 55/7206 0.000485238967325 ko04973 Carbohydrate digestion and absorption 6/186 42/7206 0.000660298333528 ko04974 Protein digestion and absorption 9/186 96/7206 0.000785330567719 ko04931 Insulin resistance 11/186 137/7206 0.000788601752356 ko04216 Ferroptosis 6/186 44/7206 0.000851375332972 ko04922 Glucagon signaling pathway 10/186 128/7206 0.00167405330158 ko05133 Pertussis 8/186 87/7206 0.00173670761764 ko04920 Adipocytokine signaling pathway 8/186 89/7206 0.00200928242823 ko00053 Ascorbate and aldarate metabolism 4/186 22/7206 0.00218346496481 ko00982 Drug metabolism - cytochrome P450 5/186 37/7206 0.00241970028876 ko05020 Prion diseases 5/186 40/7206 0.00343184092136 ko00980 Metabolism of xenobiotics by cytochrome P450 5/186 40/7206 0.00343184092136 ko00340 Histidine metabolism 4/186 25/7206 0.00355478142279 ko00040 Pentose and glucuronate interconversions 4/186 26/7206 0.00411757882011 ko00830 Retinol metabolism 5/186 42/7206 0.00425627231447 ko00770 Pantothenate and CoA biosynthesis 3/186 14/7206 0.00499290826756 ko04964 Proximal tubule bicarbonate reclamation 4/186 29/7206 0.00615974633639 ko00232 Caffeine metabolism 2/186 5/7206 0.00629545368364 ko00620 Pyruvate metabolism 5/186 46/7206 0.00631311045331 ko05166 HTLV-I infection 1/186 292/7206 0.0072293279025 ko05204 Chemical carcinogenesis 5/186 48/7206 0.0075666990695 ko04152 AMPK signaling pathway 10/186 161/7206 0.00862297384241 ko00860 Porphyrin and chlorophyll metabolism 4/186 34/7206 0.0108841402452 ko00010 Glycolysis / Gluconeogenesis 6/186 74/7206 0.0118258867264 ko00020 Citrate cycle (TCA cycle) 4/186 35/7206 0.0120461361494 ko00500 Starch and sucrose metabolism 4/186 35/7206 0.0120461361494 ko05322 Systemic lupus erythematosus 9/186 151/7206 0.0159675401162 ko00250 Alanine, aspartate and glutamate metabolism 4/186 38/7206 0.0159985995321 ko02010 ABC transporters 4/186 39/7206 0.0174766232037 ko00140 Steroid hormone biosynthesis 4/186 41/7206 0.0206813680165 ko01230 Biosynthesis of amino acids 6/186 85/7206 0.0221629375863 ko00072 Synthesis and degradation of ketone bodies 2/186 10/7206 0.0260218077445 ko00071 Fatty acid degradation 4/186 45/7206 0.0281146105893 ko00650 Butanoate metabolism 3/186 26/7206 0.0284463649554 ko04360 Axon guidance 1/186 233/7206 0.0322787178763 ko00270 Cysteine and methionine metabolism 4/186 47/7206 0.0323556772343 ko05140 Leishmaniasis 5/186 75/7206 0.0438835348427 ko00590 Arachidonic acid metabolism 4/186 52/7206 0.0445161435642 ko05016 Huntington's disease 1/186 215/7206 0.0459026174419