ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	24/306	56/7206	6.18849133135e-19
ko04080	Neuroactive ligand-receptor interaction	56/306	423/7206	6.24008221122e-15
ko04724	Glutamatergic synapse	29/306	152/7206	4.86343711388e-12
ko04728	Dopaminergic synapse	31/306	185/7206	2.98706252419e-11
ko04723	Retrograde endocannabinoid signaling	30/306	175/7206	3.51639285108e-11
ko04727	GABAergic synapse	23/306	110/7206	1.25409794222e-10
ko05032	Morphine addiction	23/306	110/7206	1.25409794222e-10
ko04024	cAMP signaling pathway	35/306	279/7206	5.4629946931e-09
ko04721	Synaptic vesicle cycle	17/306	80/7206	2.72608891049e-08
ko04713	Circadian entrainment	21/306	136/7206	2.25460040233e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	15/306	74/7206	3.51926792103e-07
ko05030	Cocaine addiction	14/306	73/7206	1.76471062184e-06
ko04726	Serotonergic synapse	19/306	137/7206	4.52421125326e-06
ko04725	Cholinergic synapse	20/306	160/7206	1.26203532081e-05
ko05031	Amphetamine addiction	14/306	91/7206	2.553225081e-05
ko04742	Taste transduction	11/306	61/7206	4.22317063169e-05
ko04360	Axon guidance	22/306	233/7206	0.000377504864733
ko04261	Adrenergic signaling in cardiomyocytes	20/306	205/7206	0.000536889152985
ko04010	MAPK signaling pathway	27/306	321/7206	0.000571314957486
ko04921	Oxytocin signaling pathway	20/306	209/7206	0.000636045750824
ko04720	Long-term potentiation	12/306	99/7206	0.000928206796971
ko04915	Estrogen signaling pathway	14/306	131/7206	0.00126628527757
ko05210	Colorectal cancer	10/306	86/7206	0.00332438311487
ko04911	Insulin secretion	12/306	117/7206	0.00389834510984
ko04071	Sphingolipid signaling pathway	15/306	162/7206	0.00440147165943
ko04060	Cytokine-cytokine receptor interaction	1/306	191/7206	0.0051900347147
ko04730	Long-term depression	9/306	78/7206	0.00552619531601
ko04072	Phospholipase D signaling pathway	17/306	197/7206	0.00585717716938
ko04217	Necroptosis	1/306	178/7206	0.00723258277925
ko04015	Rap1 signaling pathway	21/306	278/7206	0.00922793918873
ko03013	RNA transport	1/306	166/7206	0.0103483738978
ko04514	Cell adhesion molecules (CAMs)	12/306	130/7206	0.0123586086303
ko04621	NOD-like receptor signaling pathway	1/306	157/7206	0.0149957857842
ko05213	Endometrial cancer	7/306	62/7206	0.0154364708148
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	8/306	79/7206	0.0183708194539
ko04666	Fc gamma R-mediated phagocytosis	11/306	122/7206	0.0190905164706
ko00604	Glycosphingolipid biosynthesis - ganglio series	3/306	14/7206	0.0194800308431
ko03040	Spliceosome	1/306	145/7206	0.0215998294958
ko05322	Systemic lupus erythematosus	1/306	151/7206	0.0221431050091
ko04540	Gap junction	11/306	128/7206	0.023513089978
ko04972	Pancreatic secretion	10/306	111/7206	0.0269416111471
ko04120	Ubiquitin mediated proteolysis	1/306	138/7206	0.0312010125874
ko04662	B cell receptor signaling pathway	8/306	88/7206	0.0327120840713
ko04964	Proximal tubule bicarbonate reclamation	4/306	29/7206	0.0327761249198
ko04260	Cardiac muscle contraction	9/306	98/7206	0.0367044098838
ko04961	Endocrine and other factor-regulated calcium reabsorption	6/306	59/7206	0.038114496424
ko02025	Biofilm formation - Pseudomonas aeruginosa	1/306	1/7206	0.0424646128226
ko00190	Oxidative phosphorylation	1/306	127/7206	0.0447253335493
ko05205	Proteoglycans in cancer	5/306	271/7206	0.0447294877529
ko05203	Viral carcinogenesis	5/306	277/7206	0.0458970266166
ko04140	Autophagy - animal	2/306	164/7206	0.0487847353893
ko05164	Influenza A	2/306	167/7206	0.0493145134072