ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	87/440	423/7206	1.43110099547e-25
ko05033	Nicotine addiction	32/440	56/7206	5.24412559259e-25
ko04724	Glutamatergic synapse	44/440	152/7206	4.1049571302e-19
ko04728	Dopaminergic synapse	46/440	185/7206	4.70499016806e-17
ko04721	Synaptic vesicle cycle	28/440	80/7206	6.56599898622e-15
ko04727	GABAergic synapse	32/440	110/7206	2.96345543256e-14
ko04723	Retrograde endocannabinoid signaling	40/440	175/7206	1.22399620288e-13
ko05032	Morphine addiction	30/440	110/7206	1.26082731377e-12
ko04713	Circadian entrainment	32/440	136/7206	1.70075959626e-11
ko05014	Amyotrophic lateral sclerosis (ALS)	21/440	74/7206	1.4622396359e-09
ko04725	Cholinergic synapse	31/440	160/7206	6.04935095946e-09
ko05030	Cocaine addiction	20/440	73/7206	7.10838281569e-09
ko05031	Amphetamine addiction	22/440	91/7206	1.58226709379e-08
ko04024	cAMP signaling pathway	41/440	279/7206	1.13497208922e-07
ko04726	Serotonergic synapse	25/440	137/7206	6.14722366691e-07
ko04744	Phototransduction	11/440	36/7206	5.79027882844e-06
ko04911	Insulin secretion	21/440	117/7206	6.46685364848e-06
ko04720	Long-term potentiation	17/440	99/7206	8.77470255428e-05
ko04514	Cell adhesion molecules (CAMs)	20/440	130/7206	0.000106906698085
ko04010	MAPK signaling pathway	37/440	321/7206	0.000172059142665
ko04261	Adrenergic signaling in cardiomyocytes	26/440	205/7206	0.00031302887513
ko04730	Long-term depression	13/440	78/7206	0.000787768324726
ko04742	Taste transduction	11/440	61/7206	0.0010069926628
ko04060	Cytokine-cytokine receptor interaction	2/440	191/7206	0.0010297464416
ko05205	Proteoglycans in cancer	5/440	271/7206	0.00109342662006
ko03040	Spliceosome	1/440	145/7206	0.00227989179604
ko04921	Oxytocin signaling pathway	24/440	209/7206	0.00285004779766
ko05164	Influenza A	2/440	167/7206	0.00294349757098
ko04360	Axon guidance	26/440	233/7206	0.00301107101187
ko04120	Ubiquitin mediated proteolysis	1/440	138/7206	0.00330001690257
ko05166	HTLV-I infection	7/440	292/7206	0.00391519179496
ko04966	Collecting duct acid secretion	6/440	26/7206	0.00404452413772
ko05203	Viral carcinogenesis	7/440	277/7206	0.00705505063087
ko04970	Salivary secretion	13/440	95/7206	0.007264061321
ko05034	Alcoholism	25/440	238/7206	0.00808612052654
ko04972	Pancreatic secretion	14/440	111/7206	0.00821961642723
ko05322	Systemic lupus erythematosus	2/440	151/7206	0.0087505491127
ko05162	Measles	1/440	120/7206	0.0104803785201
ko04071	Sphingolipid signaling pathway	18/440	162/7206	0.0119325959129
ko05110	Vibrio cholerae infection	9/440	63/7206	0.0135710152862
ko00240	Pyrimidine metabolism	1/440	110/7206	0.0144456066418
ko04260	Cardiac muscle contraction	12/440	98/7206	0.017697219978
ko04611	Platelet activation	3/440	163/7206	0.0188121593029
ko04140	Autophagy - animal	3/440	164/7206	0.0190523529127
ko04218	Cellular senescence	4/440	177/7206	0.0253385577099
ko04961	Endocrine and other factor-regulated calcium reabsorption	8/440	59/7206	0.025911873251
ko05168	Herpes simplex infection	4/440	182/7206	0.0262085930531
ko04621	NOD-like receptor signaling pathway	3/440	157/7206	0.0262333684862
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	10/440	79/7206	0.0279498850981
ko04145	Phagosome	17/440	162/7206	0.0287226922847
ko04014	Ras signaling pathway	26/440	279/7206	0.0292441588538
ko00564	Glycerophospholipid metabolism	1/440	99/7206	0.0310084060078
ko00230	Purine metabolism	5/440	194/7206	0.0328694968036
ko04211	Longevity regulating pathway	2/440	123/7206	0.0342652997246
ko04925	Aldosterone synthesis and secretion	12/440	105/7206	0.0358662637473
ko04510	Focal adhesion	7/440	240/7206	0.0381734616047
ko04915	Estrogen signaling pathway	14/440	131/7206	0.0397004384015
ko05016	Huntington's disease	6/440	215/7206	0.0412775971937
ko03013	RNA transport	4/440	166/7206	0.0469015868497
ko00604	Glycosphingolipid biosynthesis - ganglio series	3/440	14/7206	0.0497424120216