ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 31/362 79/7206 1.48901676039e-20 ko04950 Maturity onset diabetes of the young 18/362 29/7206 5.73173479068e-17 ko04975 Fat digestion and absorption 14/362 35/7206 4.50326098772e-10 ko04974 Protein digestion and absorption 21/362 96/7206 7.23001395947e-09 ko00260 Glycine, serine and threonine metabolism 13/362 48/7206 4.06870748474e-07 ko04978 Mineral absorption 10/362 40/7206 1.97918408352e-05 ko04976 Bile secretion 14/362 80/7206 3.69675718135e-05 ko05150 Staphylococcus aureus infection 9/362 36/7206 5.18530693543e-05 ko04977 Vitamin digestion and absorption 7/362 22/7206 6.74216723694e-05 ko05217 Basal cell carcinoma 12/362 68/7206 0.000122108725648 ko04512 ECM-receptor interaction 13/362 79/7206 0.000134836531931 ko04614 Renin-angiotensin system 6/362 18/7206 0.000170977399327 ko00040 Pentose and glucuronate interconversions 7/362 26/7206 0.00021840581125 ko05169 Epstein-Barr virus infection 1/362 206/7206 0.000503409695381 ko05034 Alcoholism 2/362 238/7206 0.000723107847856 ko00480 Glutathione metabolism 9/362 55/7206 0.00150457447866 ko05016 Huntington's disease 2/362 215/7206 0.00216229881509 ko05161 Hepatitis B 1/362 173/7206 0.00228298455385 ko04217 Necroptosis 1/362 178/7206 0.00244017543637 ko05203 Viral carcinogenesis 4/362 277/7206 0.00283060430183 ko01230 Biosynthesis of amino acids 11/362 85/7206 0.00331860824558 ko03013 RNA transport 1/362 166/7206 0.00335102329104 ko00591 Linoleic acid metabolism 5/362 22/7206 0.00403296466772 ko04973 Carbohydrate digestion and absorption 7/362 42/7206 0.0044804424794 ko04062 Chemokine signaling pathway 2/362 201/7206 0.00452501732606 ko05012 Parkinson's disease 1/362 155/7206 0.0048204575839 ko04621 NOD-like receptor signaling pathway 1/362 157/7206 0.00484293331652 ko04010 MAPK signaling pathway 6/362 321/7206 0.00554099106647 ko01200 Carbon metabolism 14/362 128/7206 0.00606646693809 ko04144 Endocytosis 7/362 342/7206 0.00720021132602 ko04724 Glutamatergic synapse 1/362 152/7206 0.00723537522803 ko03320 PPAR signaling pathway 9/362 69/7206 0.00723583451894 ko04340 Hedgehog signaling pathway 8/362 58/7206 0.00795618342649 ko00270 Cysteine and methionine metabolism 7/362 47/7206 0.00842746763088 ko04141 Protein processing in endoplasmic reticulum 2/362 184/7206 0.00903240293283 ko00982 Drug metabolism - cytochrome P450 6/362 37/7206 0.00955340289887 ko00710 Carbon fixation in photosynthetic organisms 5/362 27/7206 0.0100621777877 ko00330 Arginine and proline metabolism 8/362 61/7206 0.0107324589387 ko02010 ABC transporters 6/362 39/7206 0.0123270414229 ko04723 Retrograde endocannabinoid signaling 2/362 175/7206 0.0126599229832 ko05010 Alzheimer's disease 3/362 202/7206 0.0135202654116 ko04964 Proximal tubule bicarbonate reclamation 5/362 29/7206 0.0136365931276 ko00980 Metabolism of xenobiotics by cytochrome P450 6/362 40/7206 0.0139068747102 ko05205 Proteoglycans in cancer 23/362 271/7206 0.0147143658945 ko04380 Osteoclast differentiation 1/362 134/7206 0.0148733589863 ko00983 Drug metabolism - other enzymes 6/362 42/7206 0.0174797449971 ko00830 Retinol metabolism 6/362 42/7206 0.0174797449971 ko00030 Pentose phosphate pathway 5/362 32/7206 0.0204575170855 ko04660 T cell receptor signaling pathway 1/362 124/7206 0.02129471284 ko00190 Oxidative phosphorylation 1/362 127/7206 0.0216776843648 ko00472 D-Arginine and D-ornithine metabolism 2/362 5/7206 0.0227474109074 ko00311 Penicillin and cephalosporin biosynthesis 2/362 5/7206 0.0227474109074 ko04931 Insulin resistance 13/362 137/7206 0.0265774466422 ko00020 Citrate cycle (TCA cycle) 5/362 35/7206 0.0291923197557 ko00770 Pantothenate and CoA biosynthesis 3/362 14/7206 0.0302749612382 ko04260 Cardiac muscle contraction 10/362 98/7206 0.0309367416883 ko05204 Chemical carcinogenesis 6/362 48/7206 0.0318475120564 ko05224 Breast cancer 15/362 174/7206 0.0345428886054 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/362 182/7206 0.0365263251675 ko00250 Alanine, aspartate and glutamate metabolism 5/362 38/7206 0.0399770174182 ko00630 Glyoxylate and dicarboxylate metabolism 5/362 38/7206 0.0399770174182 ko05032 Morphine addiction 1/362 110/7206 0.0446237202119 ko00590 Arachidonic acid metabolism 6/362 52/7206 0.0447725455879 ko04550 Signaling pathways regulating pluripotency of stem cells 14/362 165/7206 0.0465995036723 ko05020 Prion diseases 5/362 40/7206 0.0483483783087 ko05164 Influenza A 3/362 167/7206 0.0485978550307 ko04510 Focal adhesion 19/362 240/7206 0.0486432907856