ko pathway ratio_in_study ratio_in_pop p_value ko04650 Natural killer cell mediated cytotoxicity 17/221 97/7206 4.36440740207e-09 ko05340 Primary immunodeficiency 10/221 30/7206 1.05513342417e-08 ko04060 Cytokine-cytokine receptor interaction 23/221 191/7206 1.51290586618e-08 ko04380 Osteoclast differentiation 17/221 134/7206 5.94714915029e-07 ko04630 Jak-STAT signaling pathway 16/221 132/7206 2.38809709063e-06 ko05140 Leishmaniasis 12/221 75/7206 2.43659745201e-06 ko04612 Antigen processing and presentation 12/221 77/7206 3.24691389803e-06 ko04659 Th17 cell differentiation 14/221 106/7206 3.74255200156e-06 ko05330 Allograft rejection 7/221 24/7206 5.14748052745e-06 ko05321 Inflammatory bowel disease (IBD) 10/221 56/7206 6.21135551955e-06 ko05164 Influenza A 17/221 167/7206 1.26809204262e-05 ko05320 Autoimmune thyroid disease 7/221 29/7206 2.03636212536e-05 ko05145 Toxoplasmosis 14/221 126/7206 2.83309112308e-05 ko04658 Th1 and Th2 cell differentiation 12/221 96/7206 3.30068586935e-05 ko04145 Phagosome 16/221 162/7206 3.34910241004e-05 ko05152 Tuberculosis 17/221 187/7206 5.51936861179e-05 ko05150 Staphylococcus aureus infection 7/221 36/7206 9.07037783605e-05 ko04660 T cell receptor signaling pathway 13/221 124/7206 0.000100742523988 ko04672 Intestinal immune network for IgA production 7/221 37/7206 0.000108986345731 ko05310 Asthma 5/221 17/7206 0.000118684114943 ko04640 Hematopoietic cell lineage 9/221 64/7206 0.000129420682026 ko05168 Herpes simplex infection 16/221 182/7206 0.000136452995626 ko05332 Graft-versus-host disease 5/221 18/7206 0.000160255541477 ko04620 Toll-like receptor signaling pathway 11/221 100/7206 0.000226101360744 ko04664 Fc epsilon RI signaling pathway 9/221 77/7206 0.000536816568607 ko04670 Leukocyte transendothelial migration 13/221 151/7206 0.000708591853817 ko05162 Measles 11/221 120/7206 0.0010836715938 ko04062 Chemokine signaling pathway 15/221 201/7206 0.00124920320296 ko05416 Viral myocarditis 7/221 55/7206 0.00134530540182 ko04611 Platelet activation 13/221 163/7206 0.00144196905696 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/221 191/7206 0.00213834136949 ko00592 alpha-Linolenic acid metabolism 4/221 19/7206 0.00232163173324 ko04940 Type I diabetes mellitus 5/221 32/7206 0.00265472696372 ko00120 Primary bile acid biosynthesis 4/221 20/7206 0.00283309157483 ko04621 NOD-like receptor signaling pathway 12/221 157/7206 0.00311006750402 ko04666 Fc gamma R-mediated phagocytosis 10/221 122/7206 0.00412763190683 ko00590 Arachidonic acid metabolism 6/221 52/7206 0.00487195007811 ko04020 Calcium signaling pathway 1/221 265/7206 0.0052601802608 ko04514 Cell adhesion molecules (CAMs) 10/221 130/7206 0.00645546798439 ko04064 NF-kappa B signaling pathway 8/221 96/7206 0.0090236652598 ko05034 Alcoholism 1/221 238/7206 0.0109734668525 ko05144 Malaria 5/221 45/7206 0.011677469751 ko04137 Mitophagy - animal 7/221 82/7206 0.0125775107939 ko05016 Huntington's disease 1/221 215/7206 0.0151332263464 ko05133 Pertussis 7/221 87/7206 0.0170141817913 ko04662 B cell receptor signaling pathway 7/221 88/7206 0.0180191405635 ko04080 Neuroactive ligand-receptor interaction 5/221 423/7206 0.0187376615443 ko05323 Rheumatoid arthritis 7/221 89/7206 0.0190652084367 ko05010 Alzheimer's disease 1/221 202/7206 0.0218635990221 ko03050 Proteasome 5/221 54/7206 0.0242426101596 ko00982 Drug metabolism - cytochrome P450 4/221 37/7206 0.0257624215548 ko00750 Vitamin B6 metabolism 2/221 9/7206 0.0292426574125 ko02010 ABC transporters 4/221 39/7206 0.0306072151426 ko04390 Hippo signaling pathway 1/221 188/7206 0.0315112468141 ko00564 Glycerophospholipid metabolism 7/221 99/7206 0.0319494915233 ko04610 Complement and coagulation cascades 6/221 79/7206 0.0337608924378 ko04622 RIG-I-like receptor signaling pathway 5/221 62/7206 0.0408301015865 ko05206 MicroRNAs in cancer 1/221 177/7206 0.0453332928231 ko04310 Wnt signaling pathway 1/221 181/7206 0.0458984785019 ko04728 Dopaminergic synapse 1/221 185/7206 0.047075923603