ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	184/1087	423/7206	4.42568476665e-48
ko04724	Glutamatergic synapse	85/1087	152/7206	4.54443364136e-32
ko05033	Nicotine addiction	45/1087	56/7206	1.35497900396e-27
ko05032	Morphine addiction	64/1087	110/7206	1.09463232841e-25
ko04713	Circadian entrainment	70/1087	136/7206	1.1240936489e-23
ko04727	GABAergic synapse	61/1087	110/7206	5.23038901448e-23
ko04728	Dopaminergic synapse	83/1087	185/7206	9.5603275805e-23
ko04725	Cholinergic synapse	74/1087	160/7206	2.36399800035e-21
ko04723	Retrograde endocannabinoid signaling	75/1087	175/7206	3.30930580048e-19
ko04024	cAMP signaling pathway	96/1087	279/7206	3.40311281472e-16
ko04721	Synaptic vesicle cycle	43/1087	80/7206	6.75546211573e-16
ko04020	Calcium signaling pathway	91/1087	265/7206	1.56023793826e-15
ko04726	Serotonergic synapse	59/1087	137/7206	1.82343742869e-15
ko04742	Taste transduction	36/1087	61/7206	3.05033499703e-15
ko04911	Insulin secretion	53/1087	117/7206	3.86510188021e-15
ko04744	Phototransduction	25/1087	36/7206	2.55364839719e-13
ko04921	Oxytocin signaling pathway	72/1087	209/7206	1.95533139217e-12
ko05031	Amphetamine addiction	40/1087	91/7206	3.11562922803e-11
ko04720	Long-term potentiation	41/1087	99/7206	1.72319451467e-10
ko04261	Adrenergic signaling in cardiomyocytes	66/1087	205/7206	4.84079895415e-10
ko03040	Spliceosome	1/1087	145/7206	2.24419773275e-09
ko04970	Salivary secretion	37/1087	95/7206	1.0132315659e-08
ko04925	Aldosterone synthesis and secretion	38/1087	105/7206	9.65007835406e-08
ko04360	Axon guidance	65/1087	233/7206	3.28140542636e-07
ko04971	Gastric acid secretion	35/1087	98/7206	4.13901813728e-07
ko04514	Cell adhesion molecules (CAMs)	42/1087	130/7206	6.63876559299e-07
ko05322	Systemic lupus erythematosus	4/1087	151/7206	7.60269139329e-07
ko05030	Cocaine addiction	28/1087	73/7206	9.15764257642e-07
ko03013	RNA transport	6/1087	166/7206	2.65171017826e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1087	74/7206	4.41034341175e-06
ko04010	MAPK signaling pathway	79/1087	321/7206	4.56044631762e-06
ko04120	Ubiquitin mediated proteolysis	4/1087	138/7206	5.37179996052e-06
ko04070	Phosphatidylinositol signaling system	36/1087	112/7206	5.99188533458e-06
ko04014	Ras signaling pathway	70/1087	279/7206	7.7839211824e-06
ko04621	NOD-like receptor signaling pathway	6/1087	157/7206	7.83124842922e-06
ko04972	Pancreatic secretion	35/1087	111/7206	1.09592794588e-05
ko04022	cGMP-PKG signaling pathway	57/1087	216/7206	1.13696415938e-05
ko05168	Herpes simplex infection	9/1087	182/7206	2.13964528492e-05
ko04740	Olfactory transduction	27/1087	80/7206	2.50720411226e-05
ko05203	Viral carcinogenesis	19/1087	277/7206	3.37940091518e-05
ko04730	Long-term depression	26/1087	78/7206	4.4378862922e-05
ko04540	Gap junction	37/1087	128/7206	5.07098769244e-05
ko04745	Phototransduction - fly	16/1087	38/7206	5.34362690151e-05
ko04141	Protein processing in endoplasmic reticulum	10/1087	184/7206	5.99581067141e-05
ko04072	Phospholipase D signaling pathway	51/1087	197/7206	6.77837304139e-05
ko04612	Antigen processing and presentation	1/1087	77/7206	7.93608381024e-05
ko04750	Inflammatory mediator regulation of TRP channels	35/1087	122/7206	9.95026317432e-05
ko04924	Renin secretion	27/1087	86/7206	0.000108753446847
ko05164	Influenza A	9/1087	167/7206	0.000112000072174
ko04966	Collecting duct acid secretion	12/1087	26/7206	0.000161473075446
ko04060	Cytokine-cytokine receptor interaction	12/1087	191/7206	0.000205485891047
ko03008	Ribosome biogenesis in eukaryotes	2/1087	79/7206	0.000412242067391
ko05414	Dilated cardiomyopathy	31/1087	112/7206	0.000477373254617
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/1087	79/7206	0.00066570662107
ko04710	Circadian rhythm	15/1087	43/7206	0.00101996840383
ko04915	Estrogen signaling pathway	34/1087	131/7206	0.00117785294119
ko04064	NF-kappa B signaling pathway	4/1087	96/7206	0.00131831582185
ko04110	Cell cycle	9/1087	145/7206	0.00141100609504
ko04260	Cardiac muscle contraction	27/1087	98/7206	0.00147367250637
ko04964	Proximal tubule bicarbonate reclamation	11/1087	29/7206	0.00220517199312
ko04626	Plant-pathogen interaction	8/1087	18/7206	0.00278332975807
ko04371	Apelin signaling pathway	41/1087	177/7206	0.00388583228669
ko04976	Bile secretion	22/1087	80/7206	0.00405093971419
ko05140	Leishmaniasis	3/1087	75/7206	0.00500968357912
ko04923	Regulation of lipolysis in adipocytes	21/1087	77/7206	0.00567442257232
ko04930	Type II diabetes mellitus	16/1087	54/7206	0.00624515931319
ko05162	Measles	8/1087	120/7206	0.00663397277326
ko05110	Vibrio cholerae infection	18/1087	63/7206	0.00675249022671
ko00240	Pyrimidine metabolism	7/1087	110/7206	0.00697116285989
ko05161	Hepatitis B	14/1087	173/7206	0.00702870643008
ko05169	Epstein-Barr virus infection	18/1087	206/7206	0.00757439180659
ko05205	Proteoglycans in cancer	26/1087	271/7206	0.00920585084816
ko04146	Peroxisome	5/1087	89/7206	0.0103583495112
ko03022	Basal transcription factors	1/1087	44/7206	0.0104661492683
ko05144	Malaria	1/1087	45/7206	0.0105992934679
ko00071	Fatty acid degradation	1/1087	45/7206	0.0105992934679
ko03420	Nucleotide excision repair	1/1087	46/7206	0.0110453183715
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1087	14/7206	0.0117669432178
ko00280	Valine, leucine and isoleucine degradation	2/1087	54/7206	0.0127266272493
ko04015	Rap1 signaling pathway	57/1087	278/7206	0.0129671541522
ko05231	Choline metabolism in cancer	31/1087	134/7206	0.0140576473809
ko05016	Huntington's disease	20/1087	215/7206	0.0152279041493
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1087	100/7206	0.0163642381808
ko04217	Necroptosis	16/1087	178/7206	0.0193913115534
ko04330	Notch signaling pathway	3/1087	62/7206	0.0195583944266
ko04622	RIG-I-like receptor signaling pathway	3/1087	62/7206	0.0195583944266
ko04214	Apoptosis - fly	4/1087	72/7206	0.0196728785733
ko00310	Lysine degradation	4/1087	73/7206	0.0199572999285
ko04912	GnRH signaling pathway	28/1087	122/7206	0.0207543683866
ko05145	Toxoplasmosis	10/1087	126/7206	0.0230538957334
ko04960	Aldosterone-regulated sodium reabsorption	12/1087	41/7206	0.025041446254
ko04610	Complement and coagulation cascades	5/1087	79/7206	0.0261379460273
ko04973	Carbohydrate digestion and absorption	12/1087	42/7206	0.0269145988713
ko04510	Focal adhesion	24/1087	240/7206	0.0271769202194
ko04062	Chemokine signaling pathway	42/1087	201/7206	0.0272159022382
ko03320	PPAR signaling pathway	4/1087	69/7206	0.0272184989851
ko00330	Arginine and proline metabolism	3/1087	61/7206	0.028710292076
ko04658	Th1 and Th2 cell differentiation	7/1087	96/7206	0.030518714877
ko04657	IL-17 signaling pathway	6/1087	87/7206	0.033444940992
ko05133	Pertussis	6/1087	87/7206	0.033444940992
ko04922	Glucagon signaling pathway	28/1087	128/7206	0.0342771202873
ko04711	Circadian rhythm - fly	5/1087	13/7206	0.0347846177892
ko00562	Inositol phosphate metabolism	21/1087	89/7206	0.0352404641596
ko03410	Base excision repair	1/1087	38/7206	0.036511055478
ko05214	Glioma	19/1087	79/7206	0.0378688000964
ko00620	Pyruvate metabolism	2/1087	46/7206	0.0380354322041
ko00260	Glycine, serine and threonine metabolism	2/1087	48/7206	0.0396705479593
ko05219	Bladder cancer	2/1087	48/7206	0.0396705479593
ko04114	Oocyte meiosis	30/1087	139/7206	0.0408251582218
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1087	59/7206	0.0416006307259
ko05206	MicroRNAs in cancer	17/1087	177/7206	0.0426047729352
ko03018	RNA degradation	6/1087	84/7206	0.0446607582164
ko04071	Sphingolipid signaling pathway	34/1087	162/7206	0.0446720238713
ko05166	HTLV-I infection	32/1087	292/7206	0.0449710968203
ko04932	Non-alcoholic fatty liver disease (NAFLD)	18/1087	182/7206	0.0462950702461
ko04115	p53 signaling pathway	5/1087	74/7206	0.0484239072642
ko04630	Jak-STAT signaling pathway	12/1087	132/7206	0.0499600328733