ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/217 191/7206 8.3014329086e-16 ko05340 Primary immunodeficiency 13/217 30/7206 8.92799290603e-13 ko04650 Natural killer cell mediated cytotoxicity 20/217 97/7206 5.52933932664e-12 ko05152 Tuberculosis 24/217 187/7206 1.35541217021e-09 ko04380 Osteoclast differentiation 20/217 134/7206 2.44216996221e-09 ko04062 Chemokine signaling pathway 23/217 201/7206 2.83727313904e-08 ko04660 T cell receptor signaling pathway 17/217 124/7206 1.46594676053e-07 ko05145 Toxoplasmosis 17/217 126/7206 1.8592521568e-07 ko05140 Leishmaniasis 13/217 75/7206 2.84269297585e-07 ko05330 Allograft rejection 8/217 24/7206 2.88588713409e-07 ko04064 NF-kappa B signaling pathway 14/217 96/7206 8.92231280855e-07 ko05320 Autoimmune thyroid disease 8/217 29/7206 1.47854877015e-06 ko04620 Toll-like receptor signaling pathway 14/217 100/7206 1.48080278253e-06 ko05164 Influenza A 18/217 167/7206 2.37957159949e-06 ko05162 Measles 15/217 120/7206 2.69162686943e-06 ko05332 Graft-versus-host disease 6/217 18/7206 9.54167628513e-06 ko04662 B cell receptor signaling pathway 12/217 88/7206 1.11949738659e-05 ko04659 Th17 cell differentiation 13/217 106/7206 1.56539493902e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/217 191/7206 1.58879974001e-05 ko05321 Inflammatory bowel disease (IBD) 9/217 56/7206 3.81574746809e-05 ko05144 Malaria 8/217 45/7206 4.90031681313e-05 ko04666 Fc gamma R-mediated phagocytosis 13/217 122/7206 7.06116192724e-05 ko05150 Staphylococcus aureus infection 7/217 36/7206 8.0823306739e-05 ko04612 Antigen processing and presentation 10/217 77/7206 9.35802355829e-05 ko04664 Fc epsilon RI signaling pathway 10/217 77/7206 9.35802355829e-05 ko04672 Intestinal immune network for IgA production 7/217 37/7206 9.7161639472e-05 ko04145 Phagosome 15/217 162/7206 0.000101008247146 ko05168 Herpes simplex infection 16/217 182/7206 0.000110124688813 ko04630 Jak-STAT signaling pathway 13/217 132/7206 0.000158802678318 ko04670 Leukocyte transendothelial migration 14/217 151/7206 0.000170013181795 ko04621 NOD-like receptor signaling pathway 14/217 157/7206 0.000256284346238 ko04940 Type I diabetes mellitus 6/217 32/7206 0.000327174368692 ko04658 Th1 and Th2 cell differentiation 10/217 96/7206 0.000584721348259 ko05161 Hepatitis B 14/217 173/7206 0.000689841469651 ko04217 Necroptosis 14/217 178/7206 0.00091431388838 ko05133 Pertussis 9/217 87/7206 0.00115217525241 ko05310 Asthma 4/217 17/7206 0.00139795367992 ko05142 Chagas disease (American trypanosomiasis) 11/217 130/7206 0.00179673862201 ko04210 Apoptosis 13/217 180/7206 0.00296767878012 ko04611 Platelet activation 12/217 163/7206 0.00364367851897 ko05323 Rheumatoid arthritis 8/217 89/7206 0.00517196215062 ko04514 Cell adhesion molecules (CAMs) 10/217 130/7206 0.00569129301471 ko05416 Viral myocarditis 6/217 55/7206 0.00589099490779 ko04640 Hematopoietic cell lineage 6/217 64/7206 0.0121920304491 ko05166 HTLV-I infection 16/217 292/7206 0.020774853223 ko04144 Endocytosis 18/217 342/7206 0.0213038617812 ko03050 Proteasome 5/217 54/7206 0.0226083941168 ko05016 Huntington's disease 1/217 215/7206 0.0227562112789 ko01524 Platinum drug resistance 6/217 76/7206 0.0264645249138 ko05132 Salmonella infection 7/217 98/7206 0.0279379116857 ko05146 Amoebiasis 7/217 99/7206 0.0293244467838 ko04610 Complement and coagulation cascades 6/217 79/7206 0.0312663029355 ko00051 Fructose and mannose metabolism 4/217 42/7206 0.0366675708561 ko04622 RIG-I-like receptor signaling pathway 5/217 62/7206 0.0382095447089 ko04310 Wnt signaling pathway 1/217 181/7206 0.0454012179311 ko04142 Lysosome 9/217 151/7206 0.0476776948829 ko05160 Hepatitis C 9/217 153/7206 0.0499196196967