ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 22/165 157/7206 5.59066328376e-12 ko05164 Influenza A 19/165 167/7206 6.35315173223e-09 ko04620 Toll-like receptor signaling pathway 14/165 100/7206 5.02650017968e-08 ko05162 Measles 15/165 120/7206 7.77148505342e-08 ko04217 Necroptosis 18/165 178/7206 1.03641360933e-07 ko04380 Osteoclast differentiation 15/165 134/7206 3.40211272118e-07 ko05161 Hepatitis B 17/165 173/7206 3.63254464702e-07 ko05168 Herpes simplex infection 17/165 182/7206 7.50214867243e-07 ko04622 RIG-I-like receptor signaling pathway 10/165 62/7206 1.16216586424e-06 ko04064 NF-kappa B signaling pathway 12/165 96/7206 1.64406180464e-06 ko05145 Toxoplasmosis 13/165 126/7206 5.37299098053e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/165 191/7206 6.74847305077e-06 ko05160 Hepatitis C 14/165 153/7206 9.5086014071e-06 ko05152 Tuberculosis 15/165 187/7206 2.23196245953e-05 ko04060 Cytokine-cytokine receptor interaction 15/165 191/7206 2.86710927316e-05 ko04210 Apoptosis 14/165 180/7206 5.94936388256e-05 ko04668 TNF signaling pathway 11/165 120/7206 8.73478193517e-05 ko05321 Inflammatory bowel disease (IBD) 7/165 56/7206 0.000262146448949 ko05140 Leishmaniasis 8/165 75/7206 0.000291972583815 ko04658 Th1 and Th2 cell differentiation 9/165 96/7206 0.000327633831479 ko04660 T cell receptor signaling pathway 10/165 124/7206 0.000521031687393 ko05340 Primary immunodeficiency 5/165 30/7206 0.000530860376584 ko05142 Chagas disease (American trypanosomiasis) 10/165 130/7206 0.00075625863773 ko04630 Jak-STAT signaling pathway 10/165 132/7206 0.000851835435332 ko04662 B cell receptor signaling pathway 8/165 88/7206 0.000864992424157 ko04672 Intestinal immune network for IgA production 5/165 37/7206 0.00142705708828 ko04612 Antigen processing and presentation 7/165 77/7206 0.001818978758 ko04623 Cytosolic DNA-sensing pathway 5/165 41/7206 0.00227933316205 ko05215 Prostate cancer 8/165 111/7206 0.00381409837708 ko03050 Proteasome 5/165 54/7206 0.00758082414761 ko04659 Th17 cell differentiation 7/165 106/7206 0.0106281754144 ko04933 AGE-RAGE signaling pathway in diabetic complications 8/165 135/7206 0.0120795605194 ko00140 Steroid hormone biosynthesis 4/165 41/7206 0.0138906049898 ko04917 Prolactin signaling pathway 6/165 87/7206 0.0144427118242 ko04657 IL-17 signaling pathway 6/165 87/7206 0.0144427118242 ko00051 Fructose and mannose metabolism 4/165 42/7206 0.0150853799981 ko05330 Allograft rejection 3/165 24/7206 0.0167624916956 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/165 92/7206 0.0185886472041 ko00040 Pentose and glucuronate interconversions 3/165 26/7206 0.0208291924298 ko00511 Other glycan degradation 3/165 26/7206 0.0208291924298 ko04666 Fc gamma R-mediated phagocytosis 7/165 122/7206 0.0216085320023 ko04624 Toll and Imd signaling pathway 4/165 49/7206 0.025260987058 ko05134 Legionellosis 5/165 74/7206 0.0268618758918 ko05169 Epstein-Barr virus infection 10/165 206/7206 0.0275128915051 ko05320 Autoimmune thyroid disease 3/165 29/7206 0.0278540324684 ko04145 Phagosome 8/165 162/7206 0.0322069846154 ko04610 Complement and coagulation cascades 5/165 79/7206 0.0343460294669 ko04931 Insulin resistance 7/165 137/7206 0.0374605425053 ko05212 Pancreatic cancer 5/165 83/7206 0.0411804049029 ko05220 Chronic myeloid leukemia 5/165 85/7206 0.0448854920642 ko00254 Aflatoxin biosynthesis 1/165 2/7206 0.0452739765214 ko05133 Pertussis 5/165 87/7206 0.0487842596579 ko04062 Chemokine signaling pathway 9/165 201/7206 0.0497852111951