ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 26/303 79/7206 3.97621114573e-17 ko04060 Cytokine-cytokine receptor interaction 35/303 191/7206 6.77978071904e-14 ko04510 Focal adhesion 36/303 240/7206 1.45784881422e-11 ko04621 NOD-like receptor signaling pathway 24/303 157/7206 3.0206618333e-08 ko04974 Protein digestion and absorption 18/303 96/7206 7.10473570685e-08 ko05146 Amoebiasis 18/303 99/7206 1.16434040014e-07 ko04151 PI3K-Akt signaling pathway 40/303 390/7206 1.34585037783e-07 ko04933 AGE-RAGE signaling pathway in diabetic complications 20/303 135/7206 7.46504138e-07 ko04668 TNF signaling pathway 18/303 120/7206 2.25199571492e-06 ko04380 Osteoclast differentiation 18/303 134/7206 1.11260191999e-05 ko05144 Malaria 10/303 45/7206 1.28128076852e-05 ko04660 T cell receptor signaling pathway 17/303 124/7206 1.48864910698e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 13/303 79/7206 2.14421596836e-05 ko04658 Th1 and Th2 cell differentiation 14/303 96/7206 4.23709592932e-05 ko04064 NF-kappa B signaling pathway 14/303 96/7206 4.23709592932e-05 ko04810 Regulation of actin cytoskeleton 26/303 264/7206 5.09391116814e-05 ko05200 Pathways in cancer 39/303 492/7206 9.94386853523e-05 ko05131 Shigellosis 12/303 82/7206 0.000144541997742 ko04611 Platelet activation 18/303 163/7206 0.000155719351434 ko04657 IL-17 signaling pathway 12/303 87/7206 0.000256376569828 ko04662 B cell receptor signaling pathway 12/303 88/7206 0.000285902346036 ko04640 Hematopoietic cell lineage 10/303 64/7206 0.000299411953556 ko05323 Rheumatoid arthritis 12/303 89/7206 0.000318266569402 ko04666 Fc gamma R-mediated phagocytosis 14/303 122/7206 0.00056540613431 ko04672 Intestinal immune network for IgA production 7/303 37/7206 0.000751706432033 ko05132 Salmonella infection 12/303 98/7206 0.000776819168683 ko05145 Toxoplasmosis 14/303 126/7206 0.000783345128436 ko05410 Hypertrophic cardiomyopathy (HCM) 12/303 100/7206 0.000931930312242 ko04620 Toll-like receptor signaling pathway 12/303 100/7206 0.000931930312242 ko05222 Small cell lung cancer 11/303 89/7206 0.00118153135664 ko00590 Arachidonic acid metabolism 8/303 52/7206 0.00133272329124 ko05166 HTLV-I infection 24/303 292/7206 0.00149152680925 ko05205 Proteoglycans in cancer 23/303 271/7206 0.0016169391605 ko04610 Complement and coagulation cascades 10/303 79/7206 0.00163210961238 ko00565 Ether lipid metabolism 7/303 42/7206 0.00164531802041 ko05164 Influenza A 16/303 167/7206 0.00240020334573 ko05418 Fluid shear stress and atherosclerosis 16/303 173/7206 0.00298193252316 ko05161 Hepatitis B 16/303 173/7206 0.00298193252316 ko05133 Pertussis 10/303 87/7206 0.00337230120968 ko05134 Legionellosis 9/303 74/7206 0.00363720324276 ko04210 Apoptosis 16/303 180/7206 0.00403353064263 ko05162 Measles 12/303 120/7206 0.00442832724133 ko05034 Alcoholism 2/303 238/7206 0.00448573007741 ko04659 Th17 cell differentiation 11/303 106/7206 0.00478053830555 ko05120 Epithelial cell signaling in Helicobacter pylori infection 10/303 92/7206 0.00505495542598 ko04912 GnRH signaling pathway 12/303 122/7206 0.00506051284413 ko04623 Cytosolic DNA-sensing pathway 6/303 41/7206 0.00682592146431 ko05414 Dilated cardiomyopathy 11/303 112/7206 0.0072264650128 ko05321 Inflammatory bowel disease (IBD) 7/303 56/7206 0.00857209062129 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/303 191/7206 0.00880608928014 ko04145 Phagosome 14/303 162/7206 0.0089661051275 ko04218 Cellular senescence 15/303 177/7206 0.011490484179 ko05142 Chagas disease (American trypanosomiasis) 12/303 130/7206 0.0119091915493 ko00591 Linoleic acid metabolism 4/303 22/7206 0.0123036707704 ko04630 Jak-STAT signaling pathway 12/303 132/7206 0.0126465988326 ko05160 Hepatitis C 13/303 153/7206 0.0133316691573 ko04622 RIG-I-like receptor signaling pathway 7/303 62/7206 0.0146893223634 ko05152 Tuberculosis 15/303 187/7206 0.0147774129953 ko05202 Transcriptional misregulation in cancer 15/303 188/7206 0.0152330373539 ko05150 Staphylococcus aureus infection 5/303 36/7206 0.016438613185 ko04217 Necroptosis 14/303 178/7206 0.0214402123638 ko04514 Cell adhesion molecules (CAMs) 11/303 130/7206 0.0241786691567 ko04072 Phospholipase D signaling pathway 15/303 197/7206 0.0278226416591 ko04015 Rap1 signaling pathway 19/303 278/7206 0.0322464531014 ko04723 Retrograde endocannabinoid signaling 2/303 175/7206 0.0349201356968 ko04115 p53 signaling pathway 7/303 74/7206 0.0352067588032 ko04670 Leukocyte transendothelial migration 12/303 151/7206 0.0359630838283 ko05016 Huntington's disease 3/303 215/7206 0.0362823942876 ko04750 Inflammatory mediator regulation of TRP channels 10/303 122/7206 0.0373101853704 ko00966 Glucosinolate biosynthesis 1/303 1/7206 0.0420482930892 ko00592 alpha-Linolenic acid metabolism 3/303 19/7206 0.0432985182735 ko04010 MAPK signaling pathway 21/303 321/7206 0.0445058186155 ko01200 Carbon metabolism 1/303 128/7206 0.0447467864931 ko00190 Oxidative phosphorylation 1/303 127/7206 0.0447713339886 ko04330 Notch signaling pathway 6/303 62/7206 0.0450241844445 ko04713 Circadian entrainment 1/303 136/7206 0.0471523108896