ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	124/778	423/7206	1.28159904459e-27
ko04724	Glutamatergic synapse	67/778	152/7206	2.32838766835e-26
ko05033	Nicotine addiction	37/778	56/7206	4.42931086321e-23
ko04727	GABAergic synapse	51/778	110/7206	1.650999091e-21
ko05032	Morphine addiction	50/778	110/7206	1.23471431779e-20
ko04721	Synaptic vesicle cycle	41/778	80/7206	1.49375370274e-19
ko04723	Retrograde endocannabinoid signaling	60/778	175/7206	3.34892770602e-17
ko04728	Dopaminergic synapse	61/778	185/7206	1.54037860322e-16
ko04713	Circadian entrainment	48/778	136/7206	1.53515860696e-14
ko04725	Cholinergic synapse	49/778	160/7206	3.80555354411e-12
ko04744	Phototransduction	21/778	36/7206	4.45813656318e-12
ko04911	Insulin secretion	40/778	117/7206	8.15535204409e-12
ko04024	cAMP signaling pathway	69/778	279/7206	1.72596114994e-11
ko04726	Serotonergic synapse	42/778	137/7206	1.32483714718e-10
ko04921	Oxytocin signaling pathway	53/778	209/7206	2.07843062639e-09
ko04020	Calcium signaling pathway	60/778	265/7206	1.35853166994e-08
ko04742	Taste transduction	23/778	61/7206	2.90693599356e-08
ko04261	Adrenergic signaling in cardiomyocytes	48/778	205/7206	1.34824867799e-07
ko04720	Long-term potentiation	29/778	99/7206	2.98082722035e-07
ko05031	Amphetamine addiction	27/778	91/7206	5.75930417976e-07
ko05203	Viral carcinogenesis	8/778	277/7206	9.51176418035e-07
ko05164	Influenza A	2/778	167/7206	1.68980820448e-06
ko04970	Salivary secretion	26/778	95/7206	4.97890392931e-06
ko04966	Collecting duct acid secretion	12/778	26/7206	5.30413728587e-06
ko05322	Systemic lupus erythematosus	2/778	151/7206	8.07293785087e-06
ko04070	Phosphatidylinositol signaling system	28/778	112/7206	1.69004785147e-05
ko05030	Cocaine addiction	21/778	73/7206	1.75466164031e-05
ko03040	Spliceosome	2/778	145/7206	1.77211615974e-05
ko04060	Cytokine-cytokine receptor interaction	5/778	191/7206	4.27339023045e-05
ko05168	Herpes simplex infection	5/778	182/7206	8.32568645729e-05
ko04514	Cell adhesion molecules (CAMs)	29/778	130/7206	0.000142921828452
ko04072	Phospholipase D signaling pathway	39/778	197/7206	0.000157088660297
ko05205	Proteoglycans in cancer	12/778	271/7206	0.000200304318236
ko04010	MAPK signaling pathway	56/778	321/7206	0.000215566622345
ko05110	Vibrio cholerae infection	17/778	63/7206	0.00025870609169
ko04972	Pancreatic secretion	25/778	111/7206	0.000290826850022
ko04022	cGMP-PKG signaling pathway	41/778	216/7206	0.000308109103851
ko03013	RNA transport	5/778	166/7206	0.000328129422102
ko04925	Aldosterone synthesis and secretion	24/778	105/7206	0.000339059863949
ko05169	Epstein-Barr virus infection	8/778	206/7206	0.000542046953248
ko04730	Long-term depression	19/778	78/7206	0.000609146153448
ko04621	NOD-like receptor signaling pathway	5/778	157/7206	0.000641663958248
ko05161	Hepatitis B	6/778	173/7206	0.000695432974934
ko04260	Cardiac muscle contraction	22/778	98/7206	0.000770402209544
ko04141	Protein processing in endoplasmic reticulum	7/778	184/7206	0.00100304290237
ko05162	Measles	3/778	120/7206	0.00150179196568
ko04630	Jak-STAT signaling pathway	4/778	132/7206	0.00162296996876
ko04971	Gastric acid secretion	21/778	98/7206	0.00166885215247
ko05166	HTLV-I infection	16/778	292/7206	0.00192853735614
ko05014	Amyotrophic lateral sclerosis (ALS)	17/778	74/7206	0.00208202514782
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/778	14/7206	0.00217458731519
ko04924	Renin secretion	19/778	86/7206	0.00229138779864
ko04964	Proximal tubule bicarbonate reclamation	9/778	29/7206	0.0025901757131
ko04612	Antigen processing and presentation	1/778	77/7206	0.00262885867037
ko03008	Ribosome biogenesis in eukaryotes	1/778	79/7206	0.00276366100438
ko04740	Olfactory transduction	18/778	80/7206	0.00289577810813
ko04210	Apoptosis	8/778	180/7206	0.00328176914616
ko04120	Ubiquitin mediated proteolysis	5/778	138/7206	0.00334617068688
ko05140	Leishmaniasis	1/778	75/7206	0.004036776006
ko04668	TNF signaling pathway	4/778	120/7206	0.00444984372397
ko04360	Axon guidance	39/778	233/7206	0.00499606213167
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/778	79/7206	0.00512913059823
ko04745	Phototransduction - fly	10/778	38/7206	0.00575198463151
ko04540	Gap junction	24/778	128/7206	0.00597047255254
ko04110	Cell cycle	6/778	145/7206	0.00635485632145
ko00562	Inositol phosphate metabolism	18/778	89/7206	0.00860401632732
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/778	59/7206	0.0100876904256
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/778	92/7206	0.0105374152454
ko04510	Focal adhesion	14/778	240/7206	0.0106530350482
ko04064	NF-kappa B signaling pathway	3/778	96/7206	0.0117427971534
ko05215	Prostate cancer	4/778	111/7206	0.0124037053472
ko05418	Fluid shear stress and atherosclerosis	9/778	173/7206	0.0128446580422
ko04640	Hematopoietic cell lineage	1/778	64/7206	0.0129569701042
ko01524	Platinum drug resistance	2/778	76/7206	0.0148603725801
ko05200	Pathways in cancer	37/778	492/7206	0.0157486345437
ko04750	Inflammatory mediator regulation of TRP channels	22/778	122/7206	0.0171917098408
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/778	15/7206	0.0172765395121
ko05414	Dilated cardiomyopathy	20/778	112/7206	0.020726993858
ko00310	Lysine degradation	2/778	73/7206	0.0213334286855
ko04657	IL-17 signaling pathway	3/778	87/7206	0.0225460663735
ko05222	Small cell lung cancer	3/778	89/7206	0.0233527860739
ko05224	Breast cancer	10/778	174/7206	0.0259387697198
ko04218	Cellular senescence	10/778	177/7206	0.0262923150063
ko00480	Glutathione metabolism	1/778	55/7206	0.026774806817
ko05321	Inflammatory bowel disease (IBD)	1/778	56/7206	0.0273796120031
ko05145	Toxoplasmosis	6/778	126/7206	0.0283841080773
ko04140	Autophagy - animal	9/778	164/7206	0.0292583335023
ko00240	Pyrimidine metabolism	5/778	110/7206	0.029592907039
ko05217	Basal cell carcinoma	2/778	68/7206	0.0301077769446
ko00512	Mucin type O-glycan biosynthesis	7/778	29/7206	0.0311667542332
ko04626	Plant-pathogen interaction	5/778	18/7206	0.0375730155714
ko04014	Ras signaling pathway	41/778	279/7206	0.038325499001
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/778	182/7206	0.0386953591965
ko04068	FoxO signaling pathway	10/778	167/7206	0.0428723602098
ko00910	Nitrogen metabolism	5/778	19/7206	0.0466107564128
ko05206	MicroRNAs in cancer	11/778	177/7206	0.0489137042031