ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 19/129 233/7206 2.52585407976e-08 ko04015 Rap1 signaling pathway 16/129 278/7206 3.26648824216e-05 ko04550 Signaling pathways regulating pluripotency of stem cells 11/129 165/7206 0.000167637157878 ko04151 PI3K-Akt signaling pathway 18/129 390/7206 0.000183523989221 ko04916 Melanogenesis 9/129 142/7206 0.000959854177623 ko05200 Pathways in cancer 19/129 492/7206 0.00122107301955 ko05206 MicroRNAs in cancer 10/129 177/7206 0.0012220995332 ko04072 Phospholipase D signaling pathway 10/129 197/7206 0.00270950086307 ko04512 ECM-receptor interaction 6/129 79/7206 0.00279896368896 ko05230 Central carbon metabolism in cancer 6/129 81/7206 0.00317455799458 ko04070 Phosphatidylinositol signaling system 7/129 112/7206 0.00382410116638 ko04014 Ras signaling pathway 12/129 279/7206 0.00411743913852 ko04310 Wnt signaling pathway 9/129 181/7206 0.00503284005645 ko05221 Acute myeloid leukemia 5/129 63/7206 0.00521459444269 ko04390 Hippo signaling pathway 9/129 188/7206 0.00642788538438 ko05146 Amoebiasis 6/129 99/7206 0.00844888253349 ko04350 TGF-beta signaling pathway 6/129 103/7206 0.0101771568273 ko05219 Bladder cancer 4/129 48/7206 0.01038409291 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/129 135/7206 0.0104319863072 ko04923 Regulation of lipolysis in adipocytes 5/129 77/7206 0.0120273536513 ko05224 Breast cancer 8/129 174/7206 0.0125977284073 ko04964 Proximal tubule bicarbonate reclamation 3/129 29/7206 0.014583104342 ko05210 Colorectal cancer 5/129 86/7206 0.0186801451512 ko04724 Glutamatergic synapse 7/129 152/7206 0.0190135299119 ko04668 TNF signaling pathway 6/129 120/7206 0.020365992274 ko04961 Endocrine and other factor-regulated calcium reabsorption 4/129 59/7206 0.0209088526887 ko04060 Cytokine-cytokine receptor interaction 8/129 191/7206 0.0209803611335 ko05222 Small cell lung cancer 5/129 89/7206 0.0213466434465 ko04666 Fc gamma R-mediated phagocytosis 6/129 122/7206 0.0219006625835 ko04725 Cholinergic synapse 7/129 160/7206 0.0244106597008 ko04071 Sphingolipid signaling pathway 7/129 162/7206 0.0259094887843 ko04640 Hematopoietic cell lineage 4/129 64/7206 0.0272768725987 ko04020 Calcium signaling pathway 10/129 265/7206 0.027759908542 ko05142 Chagas disease (American trypanosomiasis) 6/129 130/7206 0.0288189480638 ko05217 Basal cell carcinoma 4/129 68/7206 0.0331216447063 ko04960 Aldosterone-regulated sodium reabsorption 3/129 41/7206 0.0364594380444 ko04914 Progesterone-mediated oocyte maturation 5/129 104/7206 0.0383557003592 ko04973 Carbohydrate digestion and absorption 3/129 42/7206 0.0387651892356 ko04925 Aldosterone synthesis and secretion 5/129 105/7206 0.0397170036136 ko04510 Focal adhesion 9/129 240/7206 0.040048258464 ko01521 EGFR tyrosine kinase inhibitor resistance 5/129 106/7206 0.0411075068964 ko04727 GABAergic synapse 5/129 110/7206 0.0469632169044 ko04370 VEGF signaling pathway 4/129 77/7206 0.0487589826315