ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	169/984	423/7206	3.33914030981e-44
ko04724	Glutamatergic synapse	76/984	152/7206	1.89328428734e-27
ko05033	Nicotine addiction	43/984	56/7206	9.29901028892e-27
ko05032	Morphine addiction	58/984	110/7206	1.10201592025e-22
ko04727	GABAergic synapse	54/984	110/7206	2.54129262059e-19
ko04713	Circadian entrainment	60/984	136/7206	1.94401010418e-18
ko04725	Cholinergic synapse	64/984	160/7206	5.7860432458e-17
ko04728	Dopaminergic synapse	69/984	185/7206	2.62457500961e-16
ko04024	cAMP signaling pathway	89/984	279/7206	9.89557032533e-16
ko04723	Retrograde endocannabinoid signaling	65/984	175/7206	2.53312482906e-15
ko04020	Calcium signaling pathway	83/984	265/7206	3.63932958381e-14
ko04360	Axon guidance	73/984	233/7206	1.74947034815e-12
ko04726	Serotonergic synapse	51/984	137/7206	2.52453157028e-12
ko04911	Insulin secretion	45/984	117/7206	1.37093315488e-11
ko04721	Synaptic vesicle cycle	34/984	80/7206	1.88831204845e-10
ko04261	Adrenergic signaling in cardiomyocytes	60/984	205/7206	2.94515831499e-09
ko04742	Taste transduction	27/984	61/7206	4.86907918057e-09
ko03040	Spliceosome	1/984	145/7206	2.3647983389e-08
ko05031	Amphetamine addiction	33/984	91/7206	4.11507894152e-08
ko04921	Oxytocin signaling pathway	58/984	209/7206	5.28705291684e-08
ko05030	Cocaine addiction	28/984	73/7206	1.11075470186e-07
ko04970	Salivary secretion	32/984	95/7206	4.67710952569e-07
ko03013	RNA transport	4/984	166/7206	8.93734449824e-07
ko04022	cGMP-PKG signaling pathway	56/984	216/7206	9.71756914282e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/984	74/7206	2.25791060404e-06
ko04720	Long-term potentiation	31/984	99/7206	4.55380329349e-06
ko04010	MAPK signaling pathway	73/984	321/7206	5.85469502931e-06
ko05322	Systemic lupus erythematosus	4/984	151/7206	5.98017062707e-06
ko04744	Phototransduction	16/984	36/7206	6.46855445293e-06
ko04070	Phosphatidylinositol signaling system	33/984	112/7206	1.00278969127e-05
ko04072	Phospholipase D signaling pathway	49/984	197/7206	1.94241669962e-05
ko05203	Viral carcinogenesis	16/984	277/7206	2.41765390207e-05
ko04730	Long-term depression	25/984	78/7206	3.22194775617e-05
ko04972	Pancreatic secretion	32/984	111/7206	3.26281532947e-05
ko04014	Ras signaling pathway	62/984	279/7206	7.83956931321e-05
ko05164	Influenza A	7/984	167/7206	8.35112160137e-05
ko04141	Protein processing in endoplasmic reticulum	9/984	184/7206	0.000125154971004
ko04514	Cell adhesion molecules (CAMs)	34/984	130/7206	0.000138621718101
ko04971	Gastric acid secretion	27/984	98/7206	0.0002705694106
ko04925	Aldosterone synthesis and secretion	28/984	105/7206	0.000446733374573
ko05168	Herpes simplex infection	10/984	182/7206	0.000611402161377
ko04610	Complement and coagulation cascades	2/984	79/7206	0.00144002626449
ko04120	Ubiquitin mediated proteolysis	7/984	138/7206	0.00158136572124
ko04060	Cytokine-cytokine receptor interaction	12/984	191/7206	0.00178419144908
ko04915	Estrogen signaling pathway	31/984	131/7206	0.00180859367591
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/984	59/7206	0.00188872343083
ko04930	Type II diabetes mellitus	16/984	54/7206	0.00204064348243
ko04621	NOD-like receptor signaling pathway	9/984	157/7206	0.0020640961806
ko04110	Cell cycle	8/984	145/7206	0.00212404643911
ko04612	Antigen processing and presentation	2/984	77/7206	0.00216130270052
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/984	79/7206	0.00242269469775
ko04540	Gap junction	30/984	128/7206	0.0025112320977
ko04146	Peroxisome	3/984	89/7206	0.00264026195174
ko05205	Proteoglycans in cancer	21/984	271/7206	0.00281081675963
ko00240	Pyrimidine metabolism	5/984	110/7206	0.00294822648212
ko04964	Proximal tubule bicarbonate reclamation	10/984	29/7206	0.00368452439139
ko04071	Sphingolipid signaling pathway	35/984	162/7206	0.00511767781381
ko05169	Epstein-Barr virus infection	15/984	206/7206	0.00522907963147
ko04924	Renin secretion	21/984	86/7206	0.00652570596991
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/984	14/7206	0.00721090307303
ko04260	Cardiac muscle contraction	23/984	98/7206	0.00724714777583
ko00590	Arachidonic acid metabolism	1/984	52/7206	0.00748020378981
ko00280	Valine, leucine and isoleucine degradation	1/984	54/7206	0.00798568519897
ko04142	Lysosome	10/984	151/7206	0.00817237419469
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/984	182/7206	0.00827677588529
ko04640	Hematopoietic cell lineage	2/984	64/7206	0.00938157430984
ko04115	p53 signaling pathway	3/984	74/7206	0.0103057966615
ko00562	Inositol phosphate metabolism	21/984	89/7206	0.011716656016
ko04710	Circadian rhythm	12/984	43/7206	0.0121598407864
ko00190	Oxidative phosphorylation	8/984	127/7206	0.0126278505792
ko04976	Bile secretion	19/984	80/7206	0.0130949506621
ko00330	Arginine and proline metabolism	2/984	61/7206	0.0135520520288
ko04371	Apelin signaling pathway	36/984	177/7206	0.0141204394905
ko04214	Apoptosis - fly	3/984	72/7206	0.0146430277614
ko04918	Thyroid hormone synthesis	20/984	86/7206	0.0163220094801
ko00620	Pyruvate metabolism	1/984	46/7206	0.0164462584602
ko03420	Nucleotide excision repair	1/984	46/7206	0.0164462584602
ko00260	Glycine, serine and threonine metabolism	1/984	48/7206	0.017502420305
ko04923	Regulation of lipolysis in adipocytes	18/984	77/7206	0.0184499142275
ko04960	Aldosterone-regulated sodium reabsorption	11/984	41/7206	0.0210505196399
ko05231	Choline metabolism in cancer	28/984	134/7206	0.0212409379599
ko04711	Circadian rhythm - fly	5/984	13/7206	0.0234573391029
ko04973	Carbohydrate digestion and absorption	11/984	42/7206	0.0243233805966
ko03022	Basal transcription factors	1/984	44/7206	0.0248205371926
ko05414	Dilated cardiomyopathy	24/984	112/7206	0.0251279326947
ko04015	Rap1 signaling pathway	51/984	278/7206	0.0255233785425
ko05133	Pertussis	5/984	87/7206	0.0272864086386
ko00480	Glutathione metabolism	2/984	55/7206	0.0280339338664
ko00980	Metabolism of xenobiotics by cytochrome P450	1/984	40/7206	0.0358927243059
ko03018	RNA degradation	5/984	84/7206	0.0369664284588
ko00983	Drug metabolism - other enzymes	1/984	42/7206	0.0380906064632
ko00310	Lysine degradation	4/984	73/7206	0.0390232786331
ko05140	Leishmaniasis	4/984	75/7206	0.040166023598
ko04622	RIG-I-like receptor signaling pathway	3/984	62/7206	0.0401739124797
ko05162	Measles	9/984	120/7206	0.0446685288674
ko04217	Necroptosis	15/984	178/7206	0.0456550145086