ko pathway ratio_in_study ratio_in_pop p_value ko05032 Morphine addiction 13/169 110/7206 1.50492165403e-06 ko05033 Nicotine addiction 7/169 56/7206 0.000303599867257 ko04144 Endocytosis 19/169 342/7206 0.000631048265857 ko04727 GABAergic synapse 9/169 110/7206 0.001058974331 ko04360 Axon guidance 14/169 233/7206 0.0010994477924 ko04071 Sphingolipid signaling pathway 11/169 162/7206 0.00142735987142 ko04550 Signaling pathways regulating pluripotency of stem cells 11/169 165/7206 0.00165475687309 ko04721 Synaptic vesicle cycle 7/169 80/7206 0.00259822053513 ko00604 Glycosphingolipid biosynthesis - ganglio series 3/169 14/7206 0.0038130337756 ko04390 Hippo signaling pathway 11/169 188/7206 0.00456655460069 ko04080 Neuroactive ligand-receptor interaction 19/169 423/7206 0.00686789225543 ko04723 Retrograde endocannabinoid signaling 10/169 175/7206 0.00793046793167 ko04725 Cholinergic synapse 9/169 160/7206 0.0127218820129 ko04933 AGE-RAGE signaling pathway in diabetic complications 8/169 135/7206 0.0138098992879 ko05210 Colorectal cancer 6/169 86/7206 0.0152667827287 ko04070 Phosphatidylinositol signaling system 7/169 112/7206 0.0159140887366 ko04710 Circadian rhythm 4/169 43/7206 0.0176966414281 ko04391 Hippo signaling pathway - fly 6/169 90/7206 0.0187378239977 ko05205 Proteoglycans in cancer 1/169 271/7206 0.022052191309 ko04072 Phospholipase D signaling pathway 10/169 197/7206 0.0259636444924 ko04921 Oxytocin signaling pathway 10/169 209/7206 0.0313814181942 ko04350 TGF-beta signaling pathway 6/169 103/7206 0.0336481066728 ko04915 Estrogen signaling pathway 7/169 131/7206 0.0340100236417 ko04925 Aldosterone synthesis and secretion 6/169 105/7206 0.0364711469518 ko04930 Type II diabetes mellitus 4/169 54/7206 0.037248868063 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5/169 79/7206 0.0374984738669 ko04024 cAMP signaling pathway 12/169 279/7206 0.0399950217668 ko04728 Dopaminergic synapse 9/169 185/7206 0.041338084851