ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 31/286 191/7206 1.20005784311e-11 ko05340 Primary immunodeficiency 11/286 30/7206 8.86398577871e-09 ko04630 Jak-STAT signaling pathway 18/286 132/7206 4.00902054615e-06 ko04650 Natural killer cell mediated cytotoxicity 15/286 97/7206 5.42652856612e-06 ko05150 Staphylococcus aureus infection 9/286 36/7206 7.88503294011e-06 ko04612 Antigen processing and presentation 13/286 77/7206 8.64388024384e-06 ko05164 Influenza A 20/286 167/7206 8.8376584264e-06 ko05321 Inflammatory bowel disease (IBD) 11/286 56/7206 9.60149677288e-06 ko04610 Complement and coagulation cascades 13/286 79/7206 1.15609633858e-05 ko04380 Osteoclast differentiation 17/286 134/7206 1.98006103245e-05 ko05330 Allograft rejection 7/286 24/7206 2.78787290364e-05 ko05140 Leishmaniasis 12/286 75/7206 3.37070037634e-05 ko04640 Hematopoietic cell lineage 11/286 64/7206 3.61286477592e-05 ko04621 NOD-like receptor signaling pathway 18/286 157/7206 4.52680591026e-05 ko04659 Th17 cell differentiation 14/286 106/7206 6.89699891037e-05 ko05162 Measles 15/286 120/7206 7.28005224835e-05 ko04658 Th1 and Th2 cell differentiation 13/286 96/7206 9.64986680409e-05 ko05320 Autoimmune thyroid disease 7/286 29/7206 0.000105967534966 ko05145 Toxoplasmosis 15/286 126/7206 0.000127777566606 ko05152 Tuberculosis 19/286 187/7206 0.000145560064976 ko04145 Phagosome 17/286 162/7206 0.000220630782812 ko05168 Herpes simplex infection 18/286 182/7206 0.000304371426291 ko05310 Asthma 5/286 17/7206 0.000397001208621 ko05332 Graft-versus-host disease 5/286 18/7206 0.000532007712836 ko04672 Intestinal immune network for IgA production 7/286 37/7206 0.000532248166488 ko04217 Necroptosis 17/286 178/7206 0.000668587911005 ko04064 NF-kappa B signaling pathway 11/286 96/7206 0.00138834971182 ko05133 Pertussis 10/286 87/7206 0.00221735039368 ko04660 T cell receptor signaling pathway 12/286 124/7206 0.00363921282126 ko00590 Arachidonic acid metabolism 7/286 52/7206 0.00416313869808 ko05416 Viral myocarditis 7/286 55/7206 0.00570838703389 ko05034 Alcoholism 2/286 238/7206 0.00626800051485 ko04390 Hippo signaling pathway 1/286 188/7206 0.00717478605784 ko04662 B cell receptor signaling pathway 9/286 88/7206 0.00788394315742 ko04940 Type I diabetes mellitus 5/286 32/7206 0.00793736661914 ko04062 Chemokine signaling pathway 16/286 201/7206 0.0085581511189 ko04670 Leukocyte transendothelial migration 13/286 151/7206 0.00890380009974 ko04666 Fc gamma R-mediated phagocytosis 11/286 122/7206 0.00890822103409 ko04664 Fc epsilon RI signaling pathway 8/286 77/7206 0.0109275582228 ko04611 Platelet activation 13/286 163/7206 0.0138744808042 ko04137 Mitophagy - animal 8/286 82/7206 0.0156282091928 ko04620 Toll-like receptor signaling pathway 9/286 100/7206 0.0174111211207 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/286 191/7206 0.0230148340889 ko00051 Fructose and mannose metabolism 5/286 42/7206 0.024335906564 ko05323 Rheumatoid arthritis 8/286 89/7206 0.0244577678098 ko04710 Circadian rhythm 5/286 43/7206 0.026674850407 ko03040 Spliceosome 1/286 145/7206 0.0312479046862 ko05144 Malaria 5/286 45/7206 0.0317710240966 ko04728 Dopaminergic synapse 2/286 185/7206 0.0349965504184 ko00592 alpha-Linolenic acid metabolism 3/286 19/7206 0.0374327743912 ko04514 Cell adhesion molecules (CAMs) 10/286 130/7206 0.0384089655784 ko05230 Central carbon metabolism in cancer 7/286 81/7206 0.0411442767938 ko00120 Primary bile acid biosynthesis 3/286 20/7206 0.04278288898 ko04713 Circadian entrainment 1/286 136/7206 0.0449011490595 ko05224 Breast cancer 2/286 174/7206 0.0488687868753 ko04723 Retrograde endocannabinoid signaling 2/286 175/7206 0.0488950129206