ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 67/372 145/7206 9.32255916959e-49 ko04110 Cell cycle 38/372 145/7206 1.61534817383e-17 ko03030 DNA replication 20/372 38/7206 1.56733411131e-16 ko04111 Cell cycle - yeast 29/372 90/7206 2.98119967491e-16 ko03013 RNA transport 36/372 166/7206 7.27897733895e-14 ko03022 Basal transcription factors 17/372 44/7206 1.7465031081e-11 ko00240 Pyrimidine metabolism 26/372 110/7206 3.17944176154e-11 ko03420 Nucleotide excision repair 17/372 46/7206 4.04702511281e-11 ko03460 Fanconi anemia pathway 17/372 51/7206 2.69142771142e-10 ko04113 Meiosis - yeast 19/372 70/7206 1.24657333236e-09 ko03430 Mismatch repair 11/372 22/7206 2.53280949952e-09 ko03015 mRNA surveillance pathway 20/372 93/7206 3.58398163557e-08 ko03440 Homologous recombination 13/372 41/7206 7.07415390185e-08 ko03020 RNA polymerase 11/372 29/7206 8.94363272256e-08 ko03008 Ribosome biogenesis in eukaryotes 16/372 79/7206 2.00121881455e-06 ko03018 RNA degradation 16/372 84/7206 4.67408425249e-06 ko04024 cAMP signaling pathway 1/372 279/7206 1.05092609634e-05 ko03410 Base excision repair 10/372 38/7206 1.53442024425e-05 ko04151 PI3K-Akt signaling pathway 4/372 390/7206 1.56761374273e-05 ko04120 Ubiquitin mediated proteolysis 19/372 138/7206 7.82013824694e-05 ko05169 Epstein-Barr virus infection 24/372 206/7206 0.00015812735251 ko00230 Purine metabolism 23/372 194/7206 0.000180399020234 ko04510 Focal adhesion 2/372 240/7206 0.000502457787742 ko05205 Proteoglycans in cancer 3/372 271/7206 0.000637549548779 ko04060 Cytokine-cytokine receptor interaction 1/372 191/7206 0.00072500456996 ko04360 Axon guidance 2/372 233/7206 0.000730564027294 ko03060 Protein export 6/372 23/7206 0.000866824156913 ko04810 Regulation of actin cytoskeleton 3/372 264/7206 0.000913544936634 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/372 182/7206 0.0010586514604 ko04728 Dopaminergic synapse 1/372 185/7206 0.00107538720549 ko04010 MAPK signaling pathway 5/372 321/7206 0.0011123588789 ko04723 Retrograde endocannabinoid signaling 1/372 175/7206 0.00154991286821 ko04371 Apelin signaling pathway 1/372 177/7206 0.00156809058251 ko04015 Rap1 signaling pathway 4/372 278/7206 0.00203775766904 ko04114 Oocyte meiosis 16/372 139/7206 0.00264256828199 ko04725 Cholinergic synapse 1/372 160/7206 0.00330591517804 ko04152 AMPK signaling pathway 1/372 161/7206 0.00332393580506 ko04071 Sphingolipid signaling pathway 1/372 162/7206 0.00335265454314 ko04611 Platelet activation 1/372 163/7206 0.00339220227952 ko04140 Autophagy - animal 1/372 164/7206 0.00344272850837 ko04724 Glutamatergic synapse 1/372 152/7206 0.00480929069288 ko03450 Non-homologous end-joining 4/372 15/7206 0.00605647968709 ko05418 Fluid shear stress and atherosclerosis 2/372 173/7206 0.00872259810153 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/372 135/7206 0.0101344290578 ko04713 Circadian entrainment 1/372 136/7206 0.0101344685209 ko04931 Insulin resistance 1/372 137/7206 0.0101642366229 ko04726 Serotonergic synapse 1/372 137/7206 0.0101642366229 ko04144 Endocytosis 8/372 342/7206 0.0118720400902 ko04068 FoxO signaling pathway 2/372 167/7206 0.0123608550284 ko04062 Chemokine signaling pathway 3/372 201/7206 0.0138609935128 ko01200 Carbon metabolism 1/372 128/7206 0.0146760382233 ko04540 Gap junction 1/372 128/7206 0.0146760382233 ko03010 Ribosome 1/372 129/7206 0.014709513466 ko05231 Choline metabolism in cancer 1/372 134/7206 0.0155060203439 ko04145 Phagosome 2/372 162/7206 0.0177559389007 ko05152 Tuberculosis 3/372 187/7206 0.0186707036571 ko03050 Proteasome 7/372 54/7206 0.0201446091253 ko05166 HTLV-I infection 24/372 292/7206 0.0211850101722 ko04912 GnRH signaling pathway 1/372 122/7206 0.0213450683211 ko04660 T cell receptor signaling pathway 1/372 124/7206 0.0217080842393 ko04914 Progesterone-mediated oocyte maturation 11/372 104/7206 0.0217771716892 ko04142 Lysosome 2/372 151/7206 0.0245642034016 ko05160 Hepatitis C 2/372 153/7206 0.0247852640603 ko05012 Parkinson's disease 2/372 155/7206 0.025214003995 ko05200 Pathways in cancer 15/372 492/7206 0.0262513040356 ko04916 Melanogenesis 2/372 142/7206 0.0344182683063 ko04014 Ras signaling pathway 7/372 279/7206 0.0379769545325 ko04925 Aldosterone synthesis and secretion 1/372 105/7206 0.0440900062302 ko04530 Tight junction 5/372 228/7206 0.0456776592055 ko04727 GABAergic synapse 1/372 110/7206 0.0459263893659 ko05032 Morphine addiction 1/372 110/7206 0.0459263893659 ko04072 Phospholipase D signaling pathway 4/372 197/7206 0.0477192932994