ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	61/563	152/7206	3.4829408042e-29
ko04080	Neuroactive ligand-receptor interaction	100/563	423/7206	1.20082856726e-25
ko05033	Nicotine addiction	35/563	56/7206	1.84977224779e-25
ko04727	GABAergic synapse	44/563	110/7206	3.30200609055e-21
ko05032	Morphine addiction	43/563	110/7206	2.75710407248e-20
ko04723	Retrograde endocannabinoid signaling	54/563	175/7206	1.2726977265e-19
ko04728	Dopaminergic synapse	53/563	185/7206	1.12432698507e-17
ko04713	Circadian entrainment	43/563	136/7206	2.9136732979e-16
ko04721	Synaptic vesicle cycle	31/563	80/7206	8.07636040388e-15
ko04725	Cholinergic synapse	44/563	160/7206	3.86307772028e-14
ko04024	cAMP signaling pathway	59/563	279/7206	5.41067320687e-13
ko04911	Insulin secretion	35/563	117/7206	1.17642272542e-12
ko04726	Serotonergic synapse	34/563	137/7206	7.00733704909e-10
ko04514	Cell adhesion molecules (CAMs)	31/563	130/7206	1.13085266493e-08
ko05030	Cocaine addiction	21/563	73/7206	8.86333299045e-08
ko04742	Taste transduction	19/563	61/7206	9.00265270258e-08
ko04744	Phototransduction	14/563	36/7206	2.03752457824e-07
ko04020	Calcium signaling pathway	46/563	265/7206	2.40680988425e-07
ko04720	Long-term potentiation	24/563	99/7206	3.77190737326e-07
ko04261	Adrenergic signaling in cardiomyocytes	38/563	205/7206	3.99811470036e-07
ko05203	Viral carcinogenesis	4/563	277/7206	3.25492738466e-06
ko05031	Amphetamine addiction	21/563	91/7206	4.72907557207e-06
ko04010	MAPK signaling pathway	48/563	321/7206	9.39689509454e-06
ko04970	Salivary secretion	21/563	95/7206	9.71993530054e-06
ko04921	Oxytocin signaling pathway	35/563	209/7206	1.72450642951e-05
ko04972	Pancreatic secretion	22/563	111/7206	3.71441230472e-05
ko04060	Cytokine-cytokine receptor interaction	2/563	191/7206	4.9099621592e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	16/563	74/7206	0.00014635137729
ko05164	Influenza A	2/563	167/7206	0.000211719195437
ko03040	Spliceosome	1/563	145/7206	0.0002163030744
ko04730	Long-term depression	16/563	78/7206	0.000279123734403
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/563	79/7206	0.000325294206947
ko05169	Epstein-Barr virus infection	4/563	206/7206	0.00049548397462
ko04925	Aldosterone synthesis and secretion	18/563	105/7206	0.00134636030947
ko04110	Cell cycle	2/563	145/7206	0.00140617595397
ko04140	Autophagy - animal	3/563	164/7206	0.00167612258824
ko04360	Axon guidance	32/563	233/7206	0.00167937164919
ko04072	Phospholipase D signaling pathway	28/563	197/7206	0.00173401206935
ko04022	cGMP-PKG signaling pathway	30/563	216/7206	0.00178370831088
ko05168	Herpes simplex infection	4/563	182/7206	0.0018552755015
ko04120	Ubiquitin mediated proteolysis	2/563	138/7206	0.00195337133979
ko04630	Jak-STAT signaling pathway	2/563	132/7206	0.00278079548639
ko04966	Collecting duct acid secretion	7/563	26/7206	0.00302995760697
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/563	14/7206	0.00315906965067
ko05322	Systemic lupus erythematosus	3/563	151/7206	0.0032745080632
ko05205	Proteoglycans in cancer	9/563	271/7206	0.00359092184098
ko04260	Cardiac muscle contraction	16/563	98/7206	0.00389992973627
ko04971	Gastric acid secretion	16/563	98/7206	0.00389992973627
ko04915	Estrogen signaling pathway	20/563	131/7206	0.00434081147926
ko04350	TGF-beta signaling pathway	1/563	103/7206	0.0045374648627
ko04068	FoxO signaling pathway	4/563	167/7206	0.00503275595316
ko05162	Measles	2/563	120/7206	0.00566739881909
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/563	182/7206	0.00717069702515
ko04930	Type II diabetes mellitus	10/563	54/7206	0.00812426179178
ko05161	Hepatitis B	5/563	173/7206	0.00959014016081
ko04621	NOD-like receptor signaling pathway	4/563	157/7206	0.00966990551996
ko05215	Prostate cancer	2/563	111/7206	0.0115515332243
ko04540	Gap junction	18/563	128/7206	0.012240317715
ko05166	HTLV-I infection	12/563	292/7206	0.013855551159
ko04146	Peroxisome	1/563	89/7206	0.0145800847594
ko04141	Protein processing in endoplasmic reticulum	6/563	184/7206	0.0170739567015
ko04550	Signaling pathways regulating pluripotency of stem cells	5/563	165/7206	0.0177877297204
ko03013	RNA transport	5/563	166/7206	0.017967180736
ko05034	Alcoholism	29/563	238/7206	0.0186490169171
ko03008	Ribosome biogenesis in eukaryotes	1/563	79/7206	0.0198304457085
ko00512	Mucin type O-glycan biosynthesis	6/563	29/7206	0.0223525480557
ko04964	Proximal tubule bicarbonate reclamation	6/563	29/7206	0.0223525480557
ko00564	Glycerophospholipid metabolism	2/563	99/7206	0.023077516333
ko04745	Phototransduction - fly	7/563	38/7206	0.0257683042275
ko00562	Inositol phosphate metabolism	13/563	89/7206	0.0260305523366
ko05110	Vibrio cholerae infection	10/563	63/7206	0.0289373990066
ko01524	Platinum drug resistance	1/563	76/7206	0.0291029455545
ko04612	Antigen processing and presentation	1/563	77/7206	0.0295384310548
ko04014	Ras signaling pathway	32/563	279/7206	0.0296202326038
ko04064	NF-kappa B signaling pathway	2/563	96/7206	0.0329351683082
ko05414	Dilated cardiomyopathy	15/563	112/7206	0.0329603017922
ko04150	mTOR signaling pathway	7/563	184/7206	0.0365765905339
ko04924	Renin secretion	12/563	86/7206	0.0416588603897
ko04973	Carbohydrate digestion and absorption	7/563	42/7206	0.0421477537238
ko04214	Apoptosis - fly	1/563	72/7206	0.0429007181835
ko00310	Lysine degradation	1/563	73/7206	0.0438021784018
ko05222	Small cell lung cancer	2/563	89/7206	0.045769807038
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/563	59/7206	0.046173422772
ko04371	Apelin signaling pathway	21/563	177/7206	0.0470472223231
ko04217	Necroptosis	7/563	178/7206	0.0477392298472