ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	65/354	145/7206	1.12803364183e-47
ko04110	Cell cycle	44/354	145/7206	7.28371594394e-24
ko03030	DNA replication	24/354	38/7206	9.39123974114e-23
ko04111	Cell cycle - yeast	32/354	90/7206	6.04127579788e-20
ko03013	RNA transport	36/354	166/7206	1.55399270878e-14
ko03460	Fanconi anemia pathway	20/354	51/7206	7.58364795289e-14
ko04113	Meiosis - yeast	22/354	70/7206	8.3900440634e-13
ko00240	Pyrimidine metabolism	27/354	110/7206	1.54430908712e-12
ko03440	Homologous recombination	16/354	41/7206	2.75942873359e-11
ko03410	Base excision repair	15/354	38/7206	9.63076715496e-11
ko03430	Mismatch repair	10/354	22/7206	2.75136184336e-08
ko03008	Ribosome biogenesis in eukaryotes	18/354	79/7206	3.17776208989e-08
ko03420	Nucleotide excision repair	13/354	46/7206	1.81372155689e-07
ko03015	mRNA surveillance pathway	18/354	93/7206	4.46280498045e-07
ko04144	Endocytosis	1/354	342/7206	9.78728216889e-07
ko05203	Viral carcinogenesis	32/354	277/7206	5.35313469136e-06
ko04015	Rap1 signaling pathway	2/354	278/7206	0.000169098999313
ko04024	cAMP signaling pathway	2/354	279/7206	0.00017153712341
ko05168	Herpes simplex infection	21/354	182/7206	0.000307810696084
ko04022	cGMP-PKG signaling pathway	1/354	216/7206	0.000338211794801
ko00230	Purine metabolism	21/354	194/7206	0.000566603630495
ko05166	HTLV-I infection	28/354	292/7206	0.000719951726134
ko05010	Alzheimer's disease	1/354	202/7206	0.000736539789146
ko04261	Adrenergic signaling in cardiomyocytes	1/354	205/7206	0.000766057911601
ko04360	Axon guidance	2/354	233/7206	0.00103306370835
ko04114	Oocyte meiosis	16/354	139/7206	0.00123037657506
ko04810	Regulation of actin cytoskeleton	3/354	264/7206	0.00126960464156
ko04530	Tight junction	2/354	228/7206	0.00151142102963
ko05152	Tuberculosis	1/354	187/7206	0.00159577045359
ko04151	PI3K-Akt signaling pathway	7/354	390/7206	0.00159669363123
ko04914	Progesterone-mediated oocyte maturation	13/354	104/7206	0.00164430645263
ko04723	Retrograde endocannabinoid signaling	1/354	175/7206	0.00227736082052
ko03020	RNA polymerase	6/354	29/7206	0.00244513690539
ko04014	Ras signaling pathway	4/354	279/7206	0.00278974784057
ko04115	p53 signaling pathway	10/354	74/7206	0.00311858858274
ko05322	Systemic lupus erythematosus	16/354	151/7206	0.00337429195691
ko04510	Focal adhesion	3/354	240/7206	0.0035612822418
ko04218	Cellular senescence	18/354	177/7206	0.00382986386847
ko05205	Proteoglycans in cancer	4/354	271/7206	0.0038720233648
ko03022	Basal transcription factors	7/354	44/7206	0.00517311788068
ko04072	Phospholipase D signaling pathway	2/354	197/7206	0.00642586586161
ko04670	Leukocyte transendothelial migration	1/354	151/7206	0.00702678056943
ko04724	Glutamatergic synapse	1/354	152/7206	0.00704497789941
ko04270	Vascular smooth muscle contraction	1/354	154/7206	0.00713937483553
ko04010	MAPK signaling pathway	6/354	321/7206	0.00755816686441
ko03018	RNA degradation	10/354	84/7206	0.00777198232105
ko05169	Epstein-Barr virus infection	19/354	206/7206	0.00779726874755
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/354	182/7206	0.00876456031111
ko04728	Dopaminergic synapse	2/354	185/7206	0.00881399311187
ko04921	Oxytocin signaling pathway	3/354	209/7206	0.0136746983705
ko04713	Circadian entrainment	1/354	136/7206	0.0148191806511
ko04062	Chemokine signaling pathway	3/354	201/7206	0.0189905959545
ko01200	Carbon metabolism	1/354	128/7206	0.021434637547
ko04915	Estrogen signaling pathway	1/354	131/7206	0.0219937244348
ko04630	Jak-STAT signaling pathway	1/354	132/7206	0.022285767235
ko03060	Protein export	4/354	23/7206	0.0241644095402
ko04725	Cholinergic synapse	2/354	160/7206	0.02478831338
ko04611	Platelet activation	2/354	163/7206	0.0253546166009
ko04390	Hippo signaling pathway	3/354	188/7206	0.025865804684
ko04912	GnRH signaling pathway	1/354	122/7206	0.0314196507508
ko04750	Inflammatory mediator regulation of TRP channels	1/354	122/7206	0.0314196507508
ko04310	Wnt signaling pathway	3/354	181/7206	0.0355819163334
ko05202	Transcriptional misregulation in cancer	16/354	188/7206	0.0372994617713
ko05222	Small cell lung cancer	9/354	89/7206	0.0409772785462
ko04727	GABAergic synapse	1/354	110/7206	0.0442603633642
ko05032	Morphine addiction	1/354	110/7206	0.0442603633642
ko04972	Pancreatic secretion	1/354	111/7206	0.0443679687978
ko04120	Ubiquitin mediated proteolysis	12/354	138/7206	0.0457227663898
ko04916	Melanogenesis	2/354	142/7206	0.0483848979138
ko05418	Fluid shear stress and atherosclerosis	3/354	173/7206	0.0487627899626
ko04371	Apelin signaling pathway	3/354	177/7206	0.0497813779678