ko pathway ratio_in_study ratio_in_pop p_value ko04371 Apelin signaling pathway 7/23 177/7206 8.42659377062e-07 ko04068 FoxO signaling pathway 6/23 167/7206 1.03073208959e-05 ko05224 Breast cancer 6/23 174/7206 1.3046941904e-05 ko01522 Endocrine resistance 5/23 124/7206 3.65276369727e-05 ko05230 Central carbon metabolism in cancer 4/23 81/7206 0.000111518876012 ko04320 Dorso-ventral axis formation 3/23 31/7206 0.000120464155969 ko04550 Signaling pathways regulating pluripotency of stem cells 5/23 165/7206 0.000142692527427 ko05206 MicroRNAs in cancer 5/23 177/7206 0.000198470322743 ko01521 EGFR tyrosine kinase inhibitor resistance 4/23 106/7206 0.000315811728689 ko05215 Prostate cancer 4/23 111/7206 0.000376729092892 ko05219 Bladder cancer 3/23 48/7206 0.000447403822267 ko05200 Pathways in cancer 7/23 492/7206 0.00062061089188 ko05213 Endometrial cancer 3/23 62/7206 0.000950213106839 ko05221 Acute myeloid leukemia 3/23 63/7206 0.000995649902805 ko04151 PI3K-Akt signaling pathway 6/23 390/7206 0.00111068085156 ko05223 Non-small cell lung cancer 3/23 66/7206 0.00114017380593 ko04015 Rap1 signaling pathway 5/23 278/7206 0.00156497074846 ko04014 Ras signaling pathway 5/23 279/7206 0.00159016011285 ko05214 Glioma 3/23 79/7206 0.00191779793407 ko04218 Cellular senescence 4/23 177/7206 0.00216165113276 ko05212 Pancreatic cancer 3/23 83/7206 0.00220981124444 ko05218 Melanoma 3/23 85/7206 0.00236563979672 ko04917 Prolactin signaling pathway 3/23 87/7206 0.00252815198101 ko04010 MAPK signaling pathway 5/23 321/7206 0.00294689738236 ko04921 Oxytocin signaling pathway 4/23 209/7206 0.00394712945175 ko04012 ErbB signaling pathway 3/23 109/7206 0.00478350767973 ko05216 Thyroid cancer 2/23 34/7206 0.00513819241579 ko04912 GnRH signaling pathway 3/23 122/7206 0.00654809936849 ko04540 Gap junction 3/23 128/7206 0.00747763603423 ko04915 Estrogen signaling pathway 3/23 131/7206 0.00797040901996 ko05231 Choline metabolism in cancer 3/23 134/7206 0.00848209516236 ko04933 AGE-RAGE signaling pathway in diabetic complications 3/23 135/7206 0.00865688996413 ko04810 Regulation of actin cytoskeleton 4/23 264/7206 0.00899587592125 ko05205 Proteoglycans in cancer 4/23 271/7206 0.0098471030547 ko04916 Melanogenesis 3/23 142/7206 0.00994032868288 ko04919 Thyroid hormone signaling pathway 3/23 143/7206 0.0101322988172 ko05166 HTLV-I infection 4/23 292/7206 0.0127144394194 ko04330 Notch signaling pathway 2/23 62/7206 0.0164073783629 ko04910 Insulin signaling pathway 3/23 172/7206 0.0166622748628 ko04310 Wnt signaling pathway 3/23 181/7206 0.0190752937649 ko04150 mTOR signaling pathway 3/23 184/7206 0.0199209635589 ko04390 Hippo signaling pathway 3/23 188/7206 0.0210807942953 ko04214 Apoptosis - fly 2/23 72/7206 0.0217540319521 ko04072 Phospholipase D signaling pathway 3/23 197/7206 0.0238256299012 ko04370 VEGF signaling pathway 2/23 77/7206 0.0246645782404 ko04664 Fc epsilon RI signaling pathway 2/23 77/7206 0.0246645782404 ko04730 Long-term depression 2/23 78/7206 0.0252649931711 ko04610 Complement and coagulation cascades 2/23 79/7206 0.025871413827 ko05220 Chronic myeloid leukemia 2/23 85/7206 0.029633782772 ko04213 Longevity regulating pathway - multiple species 2/23 86/7206 0.0302811096423 ko05210 Colorectal cancer 2/23 86/7206 0.0302811096423 ko04662 B cell receptor signaling pathway 2/23 88/7206 0.0315927756434 ko04360 Axon guidance 3/23 233/7206 0.0366804179967 ko05211 Renal cell carcinoma 2/23 96/7206 0.0370605434894 ko04658 Th1 and Th2 cell differentiation 2/23 96/7206 0.0370605434894 ko04650 Natural killer cell mediated cytotoxicity 2/23 97/7206 0.0377682529746 ko04720 Long-term potentiation 2/23 99/7206 0.039199413262 ko04520 Adherens junction 2/23 103/7206 0.0421236535889