ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	186/1119	423/7206	1.79202465839e-47
ko04724	Glutamatergic synapse	85/1119	152/7206	4.17365534708e-31
ko05033	Nicotine addiction	45/1119	56/7206	4.85483085294e-27
ko05032	Morphine addiction	65/1119	110/7206	7.18300683375e-26
ko04713	Circadian entrainment	72/1119	136/7206	1.63713022154e-24
ko04727	GABAergic synapse	60/1119	110/7206	1.75502474136e-21
ko04728	Dopaminergic synapse	82/1119	185/7206	3.2158271888e-21
ko04024	cAMP signaling pathway	104/1119	279/7206	1.79211665223e-19
ko04020	Calcium signaling pathway	99/1119	265/7206	7.52425397563e-19
ko04725	Cholinergic synapse	70/1119	160/7206	6.95436446176e-18
ko04723	Retrograde endocannabinoid signaling	72/1119	175/7206	1.37195312505e-16
ko04721	Synaptic vesicle cycle	44/1119	80/7206	2.95931742466e-16
ko04921	Oxytocin signaling pathway	79/1119	209/7206	1.68864546762e-15
ko04911	Insulin secretion	54/1119	117/7206	2.79563285692e-15
ko04726	Serotonergic synapse	59/1119	137/7206	7.08414969523e-15
ko05031	Amphetamine addiction	43/1119	91/7206	7.27350513352e-13
ko04742	Taste transduction	33/1119	61/7206	3.04235138819e-12
ko04720	Long-term potentiation	43/1119	99/7206	2.4570717452e-11
ko04970	Salivary secretion	41/1119	95/7206	9.1771460344e-11
ko04261	Adrenergic signaling in cardiomyocytes	68/1119	205/7206	2.08428673545e-10
ko04925	Aldosterone synthesis and secretion	43/1119	105/7206	2.47795913378e-10
ko03010	Ribosome	1/1119	129/7206	1.08958296983e-08
ko04022	cGMP-PKG signaling pathway	66/1119	216/7206	1.61751489957e-08
ko04971	Gastric acid secretion	38/1119	98/7206	1.67564177805e-08
ko04744	Phototransduction	20/1119	36/7206	3.40771706112e-08
ko04070	Phosphatidylinositol signaling system	40/1119	112/7206	1.08412738837e-07
ko03040	Spliceosome	3/1119	145/7206	1.52933555471e-07
ko05322	Systemic lupus erythematosus	4/1119	151/7206	3.21330034566e-07
ko05030	Cocaine addiction	29/1119	73/7206	4.57282582777e-07
ko04060	Cytokine-cytokine receptor interaction	8/1119	191/7206	8.07715993371e-07
ko04010	MAPK signaling pathway	83/1119	321/7206	1.16961478529e-06
ko04072	Phospholipase D signaling pathway	57/1119	197/7206	1.18299023624e-06
ko04730	Long-term depression	29/1119	78/7206	2.2994244195e-06
ko05168	Herpes simplex infection	8/1119	182/7206	3.46449329456e-06
ko05203	Viral carcinogenesis	18/1119	277/7206	5.83521546653e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1119	74/7206	1.12345955876e-05
ko04740	Olfactory transduction	28/1119	80/7206	1.43938870475e-05
ko04745	Phototransduction - fly	17/1119	38/7206	1.7550335837e-05
ko03013	RNA transport	8/1119	166/7206	1.92532676914e-05
ko04110	Cell cycle	6/1119	145/7206	2.22445422131e-05
ko04972	Pancreatic secretion	35/1119	111/7206	2.67897027687e-05
ko04750	Inflammatory mediator regulation of TRP channels	36/1119	122/7206	7.31531081122e-05
ko04360	Axon guidance	59/1119	233/7206	9.62452003611e-05
ko04922	Glucagon signaling pathway	37/1119	128/7206	0.000104260867137
ko04710	Circadian rhythm	17/1119	43/7206	0.00011866173521
ko04014	Ras signaling pathway	67/1119	279/7206	0.000186070197994
ko04514	Cell adhesion molecules (CAMs)	37/1119	130/7206	0.000193322193783
ko04915	Estrogen signaling pathway	37/1119	131/7206	0.000204925673824
ko04621	NOD-like receptor signaling pathway	9/1119	157/7206	0.000206931577038
ko05164	Influenza A	10/1119	167/7206	0.000207042385119
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/1119	79/7206	0.000264807883285
ko04141	Protein processing in endoplasmic reticulum	12/1119	184/7206	0.000270408904791
ko04540	Gap junction	36/1119	128/7206	0.000284067478742
ko04270	Vascular smooth muscle contraction	41/1119	154/7206	0.000414461382559
ko03008	Ribosome biogenesis in eukaryotes	2/1119	79/7206	0.000424724122263
ko04924	Renin secretion	26/1119	86/7206	0.00047531213635
ko04371	Apelin signaling pathway	45/1119	177/7206	0.000683242429792
ko04120	Ubiquitin mediated proteolysis	8/1119	138/7206	0.000767186442705
ko04966	Collecting duct acid secretion	11/1119	26/7206	0.00097624744613
ko04260	Cardiac muscle contraction	28/1119	98/7206	0.00101295543306
ko04973	Carbohydrate digestion and absorption	15/1119	42/7206	0.00104922982318
ko05169	Epstein-Barr virus infection	16/1119	206/7206	0.00117820515763
ko04630	Jak-STAT signaling pathway	8/1119	132/7206	0.00142895563872
ko05231	Choline metabolism in cancer	35/1119	134/7206	0.00153976585438
ko00520	Amino sugar and nucleotide sugar metabolism	1/1119	55/7206	0.00212889723507
ko05414	Dilated cardiomyopathy	30/1119	112/7206	0.00218152125276
ko04612	Antigen processing and presentation	3/1119	77/7206	0.00228012422139
ko05110	Vibrio cholerae infection	19/1119	63/7206	0.00273937062716
ko04964	Proximal tubule bicarbonate reclamation	11/1119	29/7206	0.00279638034697
ko04626	Plant-pathogen interaction	8/1119	18/7206	0.00335952007872
ko04960	Aldosterone-regulated sodium reabsorption	14/1119	41/7206	0.00346387307956
ko00562	Inositol phosphate metabolism	24/1119	89/7206	0.00479366152132
ko05162	Measles	8/1119	120/7206	0.00483643184885
ko04976	Bile secretion	22/1119	80/7206	0.00500640363283
ko04918	Thyroid hormone synthesis	23/1119	86/7206	0.00654743354493
ko04015	Rap1 signaling pathway	60/1119	278/7206	0.00666785114125
ko04923	Regulation of lipolysis in adipocytes	21/1119	77/7206	0.0068654051898
ko05144	Malaria	1/1119	45/7206	0.00690473553036
ko03420	Nucleotide excision repair	1/1119	46/7206	0.00690561997409
ko04610	Complement and coagulation cascades	4/1119	79/7206	0.00717199312216
ko04930	Type II diabetes mellitus	16/1119	54/7206	0.00748727959625
ko05321	Inflammatory bowel disease (IBD)	2/1119	56/7206	0.00862539867904
ko04064	NF-kappa B signaling pathway	6/1119	96/7206	0.00986549586203
ko05140	Leishmaniasis	4/1119	75/7206	0.00994140802605
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1119	59/7206	0.00996107290943
ko04657	IL-17 signaling pathway	5/1119	87/7206	0.0103431106462
ko05161	Hepatitis B	15/1119	173/7206	0.0103899521459
ko03022	Basal transcription factors	1/1119	44/7206	0.0104987623018
ko05214	Glioma	21/1119	79/7206	0.0113517191096
ko04217	Necroptosis	16/1119	178/7206	0.0118634966308
ko05410	Hypertrophic cardiomyopathy (HCM)	25/1119	100/7206	0.0119653092408
ko00280	Valine, leucine and isoleucine degradation	2/1119	54/7206	0.0127109583654
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1119	14/7206	0.0135401320167
ko04912	GnRH signaling pathway	29/1119	122/7206	0.0159655113361
ko00240	Pyrimidine metabolism	8/1119	110/7206	0.0160058602237
ko05166	HTLV-I infection	31/1119	292/7206	0.0166076205451
ko04146	Peroxisome	6/1119	89/7206	0.0179428840575
ko00590	Arachidonic acid metabolism	2/1119	52/7206	0.0188735744171
ko04330	Notch signaling pathway	3/1119	62/7206	0.02009259955
ko04622	RIG-I-like receptor signaling pathway	3/1119	62/7206	0.02009259955
ko04658	Th1 and Th2 cell differentiation	7/1119	96/7206	0.0225768142188
ko00010	Glycolysis / Gluconeogenesis	19/1119	74/7206	0.0225868485191
ko03410	Base excision repair	1/1119	38/7206	0.0229122512101
ko05133	Pertussis	6/1119	87/7206	0.02441616426
ko04916	Melanogenesis	32/1119	142/7206	0.0255815429833
ko05219	Bladder cancer	2/1119	48/7206	0.0262367129055
ko04350	TGF-beta signaling pathway	8/1119	103/7206	0.0275627753218
ko04114	Oocyte meiosis	31/1119	139/7206	0.0326003560504
ko05145	Toxoplasmosis	11/1119	126/7206	0.0341533463931
ko04213	Longevity regulating pathway - multiple species	21/1119	86/7206	0.0342461014973
ko04115	p53 signaling pathway	5/1119	74/7206	0.0350925180445
ko04640	Hematopoietic cell lineage	4/1119	64/7206	0.0370218113637
ko04550	Signaling pathways regulating pluripotency of stem cells	16/1119	165/7206	0.0381860336974
ko00480	Glutathione metabolism	3/1119	55/7206	0.0382834021255
ko04711	Circadian rhythm - fly	5/1119	13/7206	0.0389306123343
ko05131	Shigellosis	6/1119	82/7206	0.0444377558516
ko04214	Apoptosis - fly	5/1119	72/7206	0.0479537139558