ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	114/686	423/7206	7.99592267331e-27
ko04744	Phototransduction	25/686	36/7206	4.2429335272e-18
ko05033	Nicotine addiction	31/686	56/7206	6.41464866132e-18
ko04724	Glutamatergic synapse	51/686	152/7206	1.25126401639e-16
ko04727	GABAergic synapse	39/686	110/7206	7.02706049308e-14
ko04976	Bile secretion	31/686	80/7206	1.77998533594e-12
ko05032	Morphine addiction	35/686	110/7206	4.80199901478e-11
ko04713	Circadian entrainment	39/686	136/7206	1.28787116825e-10
ko04972	Pancreatic secretion	33/686	111/7206	1.26511997252e-09
ko04974	Protein digestion and absorption	29/686	96/7206	8.61228020383e-09
ko04740	Olfactory transduction	26/686	80/7206	9.30939819238e-09
ko04723	Retrograde endocannabinoid signaling	42/686	175/7206	9.8745457378e-09
ko04742	Taste transduction	21/686	61/7206	8.15282828195e-08
ko05203	Viral carcinogenesis	5/686	277/7206	3.0262969621e-07
ko04726	Serotonergic synapse	33/686	137/7206	3.55083997915e-07
ko04911	Insulin secretion	29/686	117/7206	9.69726983757e-07
ko04728	Dopaminergic synapse	39/686	185/7206	1.41289073377e-06
ko04970	Salivary secretion	25/686	95/7206	1.67214081461e-06
ko04020	Calcium signaling pathway	50/686	265/7206	1.76650156755e-06
ko04024	cAMP signaling pathway	52/686	279/7206	1.83017918899e-06
ko04725	Cholinergic synapse	35/686	160/7206	1.91364047786e-06
ko05030	Cocaine addiction	21/686	73/7206	2.4079911397e-06
ko05169	Epstein-Barr virus infection	3/686	206/7206	2.9786234728e-06
ko05166	HTLV-I infection	8/686	292/7206	5.87629001942e-06
ko05031	Amphetamine addiction	23/686	91/7206	9.0667257886e-06
ko04978	Mineral absorption	14/686	40/7206	9.73094344931e-06
ko04110	Cell cycle	1/686	145/7206	1.12665691037e-05
ko05205	Proteoglycans in cancer	8/686	271/7206	3.13286219636e-05
ko04924	Renin secretion	20/686	86/7206	0.000122610177243
ko04550	Signaling pathways regulating pluripotency of stem cells	3/686	165/7206	0.00012646946784
ko03013	RNA transport	3/686	166/7206	0.000130017301142
ko04120	Ubiquitin mediated proteolysis	2/686	138/7206	0.000191668746408
ko04964	Proximal tubule bicarbonate reclamation	10/686	29/7206	0.000213999990982
ko04390	Hippo signaling pathway	5/686	188/7206	0.000352975128272
ko05322	Systemic lupus erythematosus	3/686	151/7206	0.000368189548063
ko04720	Long-term potentiation	21/686	99/7206	0.000377085039056
ko04721	Synaptic vesicle cycle	18/686	80/7206	0.000408733694322
ko05164	Influenza A	4/686	167/7206	0.000438457782708
ko05168	Herpes simplex infection	5/686	182/7206	0.000491775186219
ko04810	Regulation of actin cytoskeleton	10/686	264/7206	0.000556391366981
ko04217	Necroptosis	5/686	178/7206	0.000686893277951
ko00350	Tyrosine metabolism	10/686	33/7206	0.0006960274219
ko02010	ABC transporters	11/686	39/7206	0.000747309959374
ko04921	Oxytocin signaling pathway	35/686	209/7206	0.000750883040485
ko04971	Gastric acid secretion	20/686	98/7206	0.000819328627185
ko04614	Renin-angiotensin system	7/686	18/7206	0.000856179409502
ko05224	Breast cancer	5/686	174/7206	0.000958326488186
ko05161	Hepatitis B	5/686	173/7206	0.000958724750873
ko04218	Cellular senescence	5/686	177/7206	0.000998969960973
ko04975	Fat digestion and absorption	10/686	35/7206	0.00115871625529
ko05211	Renal cell carcinoma	1/686	96/7206	0.00129171666867
ko05152	Tuberculosis	6/686	187/7206	0.00140826937638
ko00830	Retinol metabolism	11/686	42/7206	0.00146528843671
ko04150	mTOR signaling pathway	6/686	184/7206	0.00197934230745
ko04925	Aldosterone synthesis and secretion	20/686	105/7206	0.00218336828838
ko05215	Prostate cancer	2/686	111/7206	0.00273075293578
ko04660	T cell receptor signaling pathway	3/686	124/7206	0.00305537705522
ko05200	Pathways in cancer	29/686	492/7206	0.0031993272588
ko04540	Gap junction	23/686	128/7206	0.00328234141079
ko00360	Phenylalanine metabolism	6/686	17/7206	0.00359969552858
ko00230	Purine metabolism	31/686	194/7206	0.00394851795593
ko05016	Huntington's disease	9/686	215/7206	0.00440182327597
ko04141	Protein processing in endoplasmic reticulum	7/686	184/7206	0.00479280908853
ko00380	Tryptophan metabolism	11/686	50/7206	0.00634177456069
ko04514	Cell adhesion molecules (CAMs)	22/686	130/7206	0.0063679520406
ko04630	Jak-STAT signaling pathway	4/686	132/7206	0.00652099086739
ko04310	Wnt signaling pathway	7/686	181/7206	0.00653336381414
ko04145	Phagosome	6/686	162/7206	0.00661723641192
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/686	182/7206	0.00663072429913
ko04658	Th1 and Th2 cell differentiation	2/686	96/7206	0.0076850977233
ko04060	Cytokine-cytokine receptor interaction	8/686	191/7206	0.00823365550873
ko00120	Primary bile acid biosynthesis	6/686	20/7206	0.00880415385511
ko00190	Oxidative phosphorylation	4/686	127/7206	0.00900084559281
ko04730	Long-term depression	15/686	78/7206	0.00969709397895
ko04261	Adrenergic signaling in cardiomyocytes	31/686	205/7206	0.0105393566159
ko04111	Cell cycle - yeast	2/686	90/7206	0.0108691522381
ko04910	Insulin signaling pathway	7/686	172/7206	0.0116993353447
ko04621	NOD-like receptor signaling pathway	6/686	157/7206	0.0123773404294
ko04510	Focal adhesion	12/686	240/7206	0.0133576909798
ko05014	Amyotrophic lateral sclerosis (ALS)	14/686	74/7206	0.0143103135054
ko04210	Apoptosis	8/686	180/7206	0.0143674284374
ko00591	Linoleic acid metabolism	6/686	22/7206	0.0143859493631
ko00983	Drug metabolism - other enzymes	9/686	42/7206	0.0154465225399
ko04973	Carbohydrate digestion and absorption	9/686	42/7206	0.0154465225399
ko04380	Osteoclast differentiation	5/686	134/7206	0.0168157129598
ko04933	AGE-RAGE signaling pathway in diabetic complications	5/686	135/7206	0.0169099553292
ko04668	TNF signaling pathway	4/686	120/7206	0.0173303239983
ko04931	Insulin resistance	5/686	137/7206	0.0173604274167
ko04022	cGMP-PKG signaling pathway	31/686	216/7206	0.0182223253395
ko05217	Basal cell carcinoma	1/686	68/7206	0.0196092018757
ko04140	Autophagy - animal	7/686	164/7206	0.0209230145596
ko04137	Mitophagy - animal	2/686	82/7206	0.0220380644123
ko05212	Pancreatic cancer	2/686	83/7206	0.0222282049492
ko03018	RNA degradation	2/686	84/7206	0.0225890648268
ko05218	Melanoma	2/686	85/7206	0.0231216233616
ko05100	Bacterial invasion of epithelial cells	3/686	99/7206	0.0234759463652
ko04620	Toll-like receptor signaling pathway	3/686	100/7206	0.0237979274354
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/686	59/7206	0.0244035856144
ko04330	Notch signaling pathway	1/686	62/7206	0.0276515521952
ko05221	Acute myeloid leukemia	1/686	63/7206	0.028086199117
ko04750	Inflammatory mediator regulation of TRP channels	19/686	122/7206	0.028447734523
ko00910	Nitrogen metabolism	5/686	19/7206	0.0289911557278
ko05145	Toxoplasmosis	5/686	126/7206	0.0307661806234
ko05130	Pathogenic Escherichia coli infection	2/686	77/7206	0.0311681344067
ko04612	Antigen processing and presentation	2/686	77/7206	0.0311681344067
ko04664	Fc epsilon RI signaling pathway	2/686	77/7206	0.0311681344067
ko03015	mRNA surveillance pathway	3/686	93/7206	0.0322632337127
ko04142	Lysosome	7/686	151/7206	0.0352875466244
ko00430	Taurine and hypotaurine metabolism	4/686	14/7206	0.0375766721586
ko05206	MicroRNAs in cancer	9/686	177/7206	0.038075394321
ko04360	Axon guidance	13/686	233/7206	0.0401321728166
ko04918	Thyroid hormone synthesis	14/686	86/7206	0.0404936000315
ko05202	Transcriptional misregulation in cancer	10/686	188/7206	0.0439713540453
ko04662	B cell receptor signaling pathway	3/686	88/7206	0.0445658851242
ko05140	Leishmaniasis	2/686	75/7206	0.0448865153223
ko00965	Betalain biosynthesis	2/686	4/7206	0.0476744082427
ko00643	Styrene degradation	2/686	4/7206	0.0476744082427
ko00290	Valine, leucine and isoleucine biosynthesis	2/686	4/7206	0.0476744082427
ko05418	Fluid shear stress and atherosclerosis	9/686	173/7206	0.0489379716102