ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 30/136 233/7206 1.83746869637e-17 ko05200 Pathways in cancer 39/136 492/7206 3.08000036776e-15 ko05217 Basal cell carcinoma 14/136 68/7206 1.91646064856e-11 ko04390 Hippo signaling pathway 20/136 188/7206 2.47186528879e-10 ko04310 Wnt signaling pathway 18/136 181/7206 6.28808882867e-09 ko04151 PI3K-Akt signaling pathway 25/136 390/7206 5.19809581677e-08 ko04550 Signaling pathways regulating pluripotency of stem cells 16/136 165/7206 6.68442387749e-08 ko05205 Proteoglycans in cancer 20/136 271/7206 1.38940078559e-07 ko05224 Breast cancer 16/136 174/7206 1.40925534938e-07 ko04340 Hedgehog signaling pathway 9/136 58/7206 1.13326284594e-06 ko05206 MicroRNAs in cancer 14/136 177/7206 5.42408140163e-06 ko04512 ECM-receptor interaction 9/136 79/7206 1.56653383341e-05 ko05212 Pancreatic cancer 9/136 83/7206 2.34725788736e-05 ko05220 Chronic myeloid leukemia 9/136 85/7206 2.84798102988e-05 ko05222 Small cell lung cancer 9/136 89/7206 4.12512822306e-05 ko04510 Focal adhesion 15/136 240/7206 4.21713546891e-05 ko05166 HTLV-I infection 16/136 292/7206 0.000112471591935 ko04391 Hippo signaling pathway - fly 8/136 90/7206 0.000276367441628 ko04150 mTOR signaling pathway 11/136 184/7206 0.000677671721926 ko04350 TGF-beta signaling pathway 8/136 103/7206 0.00069044553121 ko04520 Adherens junction 8/136 103/7206 0.00069044553121 ko04015 Rap1 signaling pathway 14/136 278/7206 0.000721515984936 ko01521 EGFR tyrosine kinase inhibitor resistance 8/136 106/7206 0.00083531150965 ko04933 AGE-RAGE signaling pathway in diabetic complications 9/136 135/7206 0.000976024636375 ko05210 Colorectal cancer 7/136 86/7206 0.00113579088125 ko04916 Melanogenesis 9/136 142/7206 0.00139570331173 ko05145 Toxoplasmosis 8/136 126/7206 0.00253930285514 ko04392 Hippo signaling pathway -multiple species 4/136 31/7206 0.00257172710041 ko04722 Neurotrophin signaling pathway 9/136 160/7206 0.00316491339126 ko04068 FoxO signaling pathway 9/136 167/7206 0.00420640266952 ko04080 Neuroactive ligand-receptor interaction 1/136 423/7206 0.00479683058536 ko05215 Prostate cancer 7/136 111/7206 0.00486621629292 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 3/136 19/7206 0.00510639139094 ko05218 Melanoma 6/136 85/7206 0.00522527057259 ko05161 Hepatitis B 9/136 173/7206 0.00529757062664 ko04341 Hedgehog signaling pathway - fly 4/136 38/7206 0.00544964522764 ko04110 Cell cycle 8/136 145/7206 0.00597581743511 ko04218 Cellular senescence 9/136 177/7206 0.00613919628605 ko04014 Ras signaling pathway 12/136 279/7206 0.00628462504273 ko05211 Renal cell carcinoma 6/136 96/7206 0.00936470487174 ko05146 Amoebiasis 6/136 99/7206 0.0108139189407 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 3/136 26/7206 0.0124469884958 ko04380 Osteoclast differentiation 7/136 134/7206 0.0131763587655 ko05140 Leishmaniasis 5/136 75/7206 0.0133646907504 ko05230 Central carbon metabolism in cancer 5/136 81/7206 0.0181487201176 ko00514 Other types of O-glycan biosynthesis 3/136 30/7206 0.0184038695463 ko05131 Shigellosis 5/136 82/7206 0.0190427975081 ko04917 Prolactin signaling pathway 5/136 87/7206 0.0239479500315 ko04974 Protein digestion and absorption 5/136 96/7206 0.034689880467 ko05142 Chagas disease (American trypanosomiasis) 6/136 130/7206 0.0360044141529 ko04514 Cell adhesion molecules (CAMs) 6/136 130/7206 0.0360044141529 ko05410 Hypertrophic cardiomyopathy (HCM) 5/136 100/7206 0.040287312648 ko04024 cAMP signaling pathway 10/136 279/7206 0.0421944880176 ko04659 Th17 cell differentiation 5/136 106/7206 0.0496605011939