ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	203/1238	423/7206	4.59020755933e-52
ko04724	Glutamatergic synapse	87/1238	152/7206	1.86806383504e-29
ko05033	Nicotine addiction	46/1238	56/7206	1.92772782781e-26
ko04713	Circadian entrainment	76/1238	136/7206	6.25797037932e-25
ko05032	Morphine addiction	65/1238	110/7206	2.57268783003e-23
ko04727	GABAergic synapse	61/1238	110/7206	5.43071358746e-20
ko04020	Calcium signaling pathway	107/1238	265/7206	7.64248614922e-20
ko04024	cAMP signaling pathway	108/1238	279/7206	2.23916859796e-18
ko04728	Dopaminergic synapse	81/1238	185/7206	9.2642822191e-18
ko04723	Retrograde endocannabinoid signaling	76/1238	175/7206	1.73216728415e-16
ko04725	Cholinergic synapse	71/1238	160/7206	4.41782677741e-16
ko04921	Oxytocin signaling pathway	81/1238	209/7206	4.74761059054e-14
ko04911	Insulin secretion	55/1238	117/7206	5.01254566416e-14
ko04721	Synaptic vesicle cycle	43/1238	80/7206	8.20017512339e-14
ko04726	Serotonergic synapse	60/1238	137/7206	1.82353394747e-13
ko04022	cGMP-PKG signaling pathway	78/1238	216/7206	1.13108460788e-11
ko04742	Taste transduction	33/1238	61/7206	5.25772835939e-11
ko05031	Amphetamine addiction	41/1238	91/7206	4.48414884293e-10
ko04970	Salivary secretion	42/1238	95/7206	5.6822376086e-10
ko04720	Long-term potentiation	43/1238	99/7206	7.02438370597e-10
ko04261	Adrenergic signaling in cardiomyocytes	71/1238	205/7206	8.05730616251e-10
ko03010	Ribosome	1/1238	129/7206	9.35456147922e-10
ko04925	Aldosterone synthesis and secretion	43/1238	105/7206	8.48362567799e-09
ko03040	Spliceosome	3/1238	145/7206	9.70632661503e-09
ko05322	Systemic lupus erythematosus	4/1238	151/7206	2.32095593721e-08
ko04744	Phototransduction	21/1238	36/7206	2.97563873496e-08
ko04070	Phosphatidylinositol signaling system	41/1238	112/7206	7.29992541618e-07
ko05203	Viral carcinogenesis	20/1238	277/7206	1.29317338715e-06
ko04072	Phospholipase D signaling pathway	61/1238	197/7206	1.8634135471e-06
ko03013	RNA transport	8/1238	166/7206	1.93672916498e-06
ko04971	Gastric acid secretion	36/1238	98/7206	2.65804524331e-06
ko04730	Long-term depression	30/1238	78/7206	6.18032781814e-06
ko05030	Cocaine addiction	28/1238	73/7206	1.35413647001e-05
ko04745	Phototransduction - fly	18/1238	38/7206	1.57230562453e-05
ko04710	Circadian rhythm	19/1238	43/7206	3.1416806515e-05
ko05168	Herpes simplex infection	12/1238	182/7206	3.64361476731e-05
ko04360	Axon guidance	65/1238	233/7206	4.10831640118e-05
ko04540	Gap junction	41/1238	128/7206	4.20180418804e-05
ko04010	MAPK signaling pathway	83/1238	321/7206	5.62457693148e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1238	74/7206	6.40868865843e-05
ko04014	Ras signaling pathway	74/1238	279/7206	6.50768017435e-05
ko04972	Pancreatic secretion	36/1238	111/7206	6.86533409329e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1238	79/7206	7.14965194712e-05
ko04740	Olfactory transduction	28/1238	80/7206	0.000127627864114
ko04110	Cell cycle	9/1238	145/7206	0.000131281334179
ko04514	Cell adhesion molecules (CAMs)	40/1238	130/7206	0.000136384282765
ko04923	Regulation of lipolysis in adipocytes	27/1238	77/7206	0.000178543032315
ko04270	Vascular smooth muscle contraction	45/1238	154/7206	0.00020139096371
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1238	79/7206	0.000230789378344
ko04924	Renin secretion	29/1238	86/7206	0.000232839353059
ko04060	Cytokine-cytokine receptor interaction	15/1238	191/7206	0.000282447907761
ko05169	Epstein-Barr virus infection	17/1238	206/7206	0.000328414058904
ko04120	Ubiquitin mediated proteolysis	9/1238	138/7206	0.000352365385984
ko04750	Inflammatory mediator regulation of TRP channels	37/1238	122/7206	0.000365738890063
ko05414	Dilated cardiomyopathy	34/1238	112/7206	0.000546572132031
ko05164	Influenza A	13/1238	167/7206	0.000561782227308
ko04915	Estrogen signaling pathway	38/1238	131/7206	0.00063900539076
ko04612	Antigen processing and presentation	3/1238	77/7206	0.000673782655839
ko04371	Apelin signaling pathway	48/1238	177/7206	0.000797039490869
ko04621	NOD-like receptor signaling pathway	12/1238	157/7206	0.000813931987199
ko04141	Protein processing in endoplasmic reticulum	16/1238	184/7206	0.00141389913263
ko04930	Type II diabetes mellitus	19/1238	54/7206	0.00152350278708
ko04922	Glucagon signaling pathway	36/1238	128/7206	0.00190827689246
ko05161	Hepatitis B	15/1238	173/7206	0.00204122169398
ko04966	Collecting duct acid secretion	11/1238	26/7206	0.00229607985908
ko04064	NF-kappa B signaling pathway	6/1238	96/7206	0.0024779588313
ko04711	Circadian rhythm - fly	7/1238	13/7206	0.00284742644661
ko05205	Proteoglycans in cancer	29/1238	271/7206	0.00304236248822
ko00520	Amino sugar and nucleotide sugar metabolism	2/1238	55/7206	0.00371767782726
ko04976	Bile secretion	24/1238	80/7206	0.00419412176471
ko03022	Basal transcription factors	1/1238	44/7206	0.00424257963454
ko04260	Cardiac muscle contraction	28/1238	98/7206	0.00437059108984
ko04630	Jak-STAT signaling pathway	11/1238	132/7206	0.00491226255854
ko04622	RIG-I-like receptor signaling pathway	3/1238	62/7206	0.00621473427571
ko04626	Plant-pathogen interaction	8/1238	18/7206	0.00639202276199
ko04015	Rap1 signaling pathway	65/1238	278/7206	0.0072649072146
ko05231	Choline metabolism in cancer	35/1238	134/7206	0.00771390972413
ko00240	Pyrimidine metabolism	9/1238	110/7206	0.0102669520789
ko04964	Proximal tubule bicarbonate reclamation	11/1238	29/7206	0.0104303633163
ko05110	Vibrio cholerae infection	19/1238	63/7206	0.0107265390821
ko04217	Necroptosis	18/1238	178/7206	0.0114541919641
ko04973	Carbohydrate digestion and absorption	14/1238	42/7206	0.0116264031944
ko05140	Leishmaniasis	5/1238	75/7206	0.0129497700487
ko03410	Base excision repair	1/1238	38/7206	0.0151408607476
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1238	100/7206	0.0153074636962
ko04146	Peroxisome	7/1238	89/7206	0.0158573896302
ko03420	Nucleotide excision repair	2/1238	46/7206	0.01714625658
ko00280	Valine, leucine and isoleucine degradation	3/1238	54/7206	0.0181304084444
ko05162	Measles	11/1238	120/7206	0.0195954374547
ko04960	Aldosterone-regulated sodium reabsorption	13/1238	41/7206	0.0206215114172
ko05133	Pertussis	7/1238	87/7206	0.0213915804986
ko00860	Porphyrin and chlorophyll metabolism	1/1238	34/7206	0.0215607264363
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1238	14/7206	0.0218779487771
ko00562	Inositol phosphate metabolism	24/1238	89/7206	0.0223987652967
ko04113	Meiosis - yeast	5/1238	70/7206	0.0245854180669
ko05230	Central carbon metabolism in cancer	22/1238	81/7206	0.0249253882485
ko05166	HTLV-I infection	36/1238	292/7206	0.0262446964057
ko05130	Pathogenic Escherichia coli infection	6/1238	77/7206	0.0318406704028
ko05214	Glioma	21/1238	79/7206	0.0345040165131
ko05131	Shigellosis	7/1238	82/7206	0.0382394155658
ko04912	GnRH signaling pathway	30/1238	122/7206	0.0385461800151
ko05145	Toxoplasmosis	13/1238	126/7206	0.0420449070644
ko04115	p53 signaling pathway	6/1238	74/7206	0.0423751752718
ko00230	Purine metabolism	44/1238	194/7206	0.0428261992661
ko04657	IL-17 signaling pathway	8/1238	87/7206	0.0454151850266
ko04210	Apoptosis	21/1238	180/7206	0.0455599579771
ko05222	Small cell lung cancer	8/1238	89/7206	0.0462119678145
ko05416	Viral myocarditis	4/1238	55/7206	0.0487200477594
ko05340	Primary immunodeficiency	1/1238	30/7206	0.0488335438405
ko04142	Lysosome	17/1238	151/7206	0.0499598197364