ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 18/100 167/7206 8.81608962522e-12 ko05168 Herpes simplex infection 18/100 182/7206 3.81009602658e-11 ko05340 Primary immunodeficiency 9/100 30/7206 1.48974758202e-10 ko05162 Measles 14/100 120/7206 7.76937813632e-10 ko04612 Antigen processing and presentation 11/100 77/7206 6.58460150342e-09 ko04064 NF-kappa B signaling pathway 11/100 96/7206 6.99289841817e-08 ko04217 Necroptosis 14/100 178/7206 1.30838877718e-07 ko04621 NOD-like receptor signaling pathway 13/100 157/7206 2.09795097167e-07 ko05152 Tuberculosis 14/100 187/7206 2.41808479818e-07 ko05145 Toxoplasmosis 11/100 126/7206 1.14267601069e-06 ko05160 Hepatitis C 12/100 153/7206 1.14553653909e-06 ko04622 RIG-I-like receptor signaling pathway 8/100 62/7206 1.89077762371e-06 ko04380 Osteoclast differentiation 11/100 134/7206 2.10942900639e-06 ko04650 Natural killer cell mediated cytotoxicity 9/100 97/7206 6.91155590928e-06 ko04620 Toll-like receptor signaling pathway 9/100 100/7206 8.88902761839e-06 ko04060 Cytokine-cytokine receptor interaction 12/100 191/7206 1.16205939055e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/100 191/7206 1.16205939055e-05 ko05161 Hepatitis B 11/100 173/7206 2.4689942851e-05 ko05320 Autoimmune thyroid disease 5/100 29/7206 4.24362610665e-05 ko04660 T cell receptor signaling pathway 9/100 124/7206 5.03861154224e-05 ko04630 Jak-STAT signaling pathway 9/100 132/7206 8.22138681893e-05 ko03050 Proteasome 6/100 54/7206 9.25845765186e-05 ko05321 Inflammatory bowel disease (IBD) 6/100 56/7206 0.000113817857546 ko05330 Allograft rejection 4/100 24/7206 0.000299757422121 ko05144 Malaria 5/100 45/7206 0.000366245626676 ko04145 Phagosome 9/100 162/7206 0.000388437787463 ko05140 Leishmaniasis 6/100 75/7206 0.000570948268958 ko05133 Pertussis 6/100 87/7206 0.00125274017905 ko04668 TNF signaling pathway 7/100 120/7206 0.00132766057772 ko04672 Intestinal immune network for IgA production 4/100 37/7206 0.00162280174945 ko05142 Chagas disease (American trypanosomiasis) 7/100 130/7206 0.00210676862637 ko04623 Cytosolic DNA-sensing pathway 4/100 41/7206 0.00238512838856 ko04210 Apoptosis 8/100 180/7206 0.00341127566843 ko04659 Th17 cell differentiation 6/100 106/7206 0.00342683419219 ko05416 Viral myocarditis 4/100 55/7206 0.00692949953754 ko05323 Rheumatoid arthritis 5/100 89/7206 0.00770278994929 ko05146 Amoebiasis 5/100 99/7206 0.0119119119598 ko05150 Staphylococcus aureus infection 3/100 36/7206 0.0132907681983 ko02010 ABC transporters 3/100 39/7206 0.0165118659753 ko00051 Fructose and mannose metabolism 3/100 42/7206 0.0201330858999 ko05310 Asthma 2/100 17/7206 0.0226430914224 ko04610 Complement and coagulation cascades 4/100 79/7206 0.0237454060683 ko04071 Sphingolipid signaling pathway 6/100 162/7206 0.0247687911315 ko05332 Graft-versus-host disease 2/100 18/7206 0.0252461260442 ko04917 Prolactin signaling pathway 4/100 87/7206 0.0323708708052 ko04514 Cell adhesion molecules (CAMs) 5/100 130/7206 0.0341608516382 ko04658 Th1 and Th2 cell differentiation 4/100 96/7206 0.0440123436616