ko pathway ratio_in_study ratio_in_pop p_value ko04710 Circadian rhythm 15/621 43/7206 1.4006147367e-06 ko04022 cGMP-PKG signaling pathway 37/621 216/7206 3.86730672384e-05 ko04020 Calcium signaling pathway 43/621 265/7206 4.49662851828e-05 ko04921 Oxytocin signaling pathway 36/621 209/7206 4.64576313315e-05 ko04110 Cell cycle 1/621 145/7206 6.25771398913e-05 ko03013 RNA transport 2/621 166/7206 6.53495997707e-05 ko03010 Ribosome 1/621 129/7206 0.000193192984302 ko00360 Phenylalanine metabolism 7/621 17/7206 0.000307786536297 ko00350 Tyrosine metabolism 10/621 33/7206 0.000312536739345 ko03040 Spliceosome 2/621 145/7206 0.000441089810944 ko04974 Protein digestion and absorption 19/621 96/7206 0.00061524852278 ko04270 Vascular smooth muscle contraction 26/621 154/7206 0.000721804226707 ko04080 Neuroactive ligand-receptor interaction 56/621 423/7206 0.000911963762044 ko04610 Complement and coagulation cascades 16/621 79/7206 0.000960327713138 ko00120 Primary bile acid biosynthesis 7/621 20/7206 0.000975406726553 ko02010 ABC transporters 10/621 39/7206 0.00133736660169 ko04972 Pancreatic secretion 20/621 111/7206 0.00161515074204 ko04750 Inflammatory mediator regulation of TRP channels 21/621 122/7206 0.0017625378071 ko04976 Bile secretion 16/621 80/7206 0.00181628788007 ko04922 Glucagon signaling pathway 22/621 128/7206 0.00202580916329 ko04925 Aldosterone synthesis and secretion 19/621 105/7206 0.00221167622881 ko00561 Glycerolipid metabolism 13/621 63/7206 0.0023587101221 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/621 4/7206 0.0023847686058 ko04744 Phototransduction 9/621 36/7206 0.00279162704153 ko05203 Viral carcinogenesis 11/621 277/7206 0.00304027976474 ko04711 Circadian rhythm - fly 5/621 13/7206 0.00335130504184 ko04070 Phosphatidylinositol signaling system 19/621 112/7206 0.00350076841501 ko05224 Breast cancer 5/621 174/7206 0.00368615445708 ko00592 alpha-Linolenic acid metabolism 6/621 19/7206 0.00408613056192 ko04713 Circadian entrainment 22/621 136/7206 0.00472568907406 ko05322 Systemic lupus erythematosus 4/621 151/7206 0.00487282251025 ko04060 Cytokine-cytokine receptor interaction 28/621 191/7206 0.00549143891244 ko00564 Glycerophospholipid metabolism 17/621 99/7206 0.00566009555907 ko00140 Steroid hormone biosynthesis 9/621 41/7206 0.00705147626817 ko00950 Isoquinoline alkaloid biosynthesis 4/621 10/7206 0.00752328003069 ko00983 Drug metabolism - other enzymes 9/621 42/7206 0.00830764438536 ko04975 Fat digestion and absorption 8/621 35/7206 0.00844667923358 ko04970 Salivary secretion 16/621 95/7206 0.00857436673264 ko00362 Benzoate degradation 3/621 6/7206 0.0104483534768 ko04971 Gastric acid secretion 16/621 98/7206 0.010539712393 ko04390 Hippo signaling pathway 7/621 188/7206 0.011843318518 ko05034 Alcoholism 10/621 238/7206 0.0129188981347 ko04120 Ubiquitin mediated proteolysis 4/621 138/7206 0.0130734379324 ko04611 Platelet activation 23/621 163/7206 0.0159771211435 ko04550 Signaling pathways regulating pluripotency of stem cells 6/621 165/7206 0.0165892420447 ko04924 Renin secretion 14/621 86/7206 0.0183285262798 ko04111 Cell cycle - yeast 2/621 90/7206 0.0225798445069 ko04391 Hippo signaling pathway - fly 2/621 90/7206 0.0225798445069 ko04261 Adrenergic signaling in cardiomyocytes 27/621 205/7206 0.0228473989333 ko00830 Retinol metabolism 8/621 42/7206 0.0248932583951 ko04072 Phospholipase D signaling pathway 26/621 197/7206 0.0276077330606 ko05217 Basal cell carcinoma 1/621 68/7206 0.0282384043524 ko05150 Staphylococcus aureus infection 7/621 36/7206 0.0314819360398 ko04150 mTOR signaling pathway 8/621 184/7206 0.0329777248347 ko00591 Linoleic acid metabolism 5/621 22/7206 0.0359169082902 ko00380 Tryptophan metabolism 9/621 50/7206 0.0361218432573 ko05200 Pathways in cancer 30/621 492/7206 0.0374529545532 ko04144 Endocytosis 19/621 342/7206 0.0378482960576 ko00643 Styrene degradation 2/621 4/7206 0.0395609500998 ko05340 Primary immunodeficiency 6/621 30/7206 0.0398260451694 ko00590 Arachidonic acid metabolism 9/621 52/7206 0.0409015175253 ko04745 Phototransduction - fly 7/621 38/7206 0.0410390774932 ko05100 Bacterial invasion of epithelial cells 3/621 99/7206 0.0456526839422 ko04725 Cholinergic synapse 21/621 160/7206 0.0457493144734 ko04930 Type II diabetes mellitus 9/621 54/7206 0.0470856584757