ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	140/816	423/7206	2.36312517442e-35
ko04724	Glutamatergic synapse	73/816	152/7206	2.73203588219e-30
ko05033	Nicotine addiction	43/816	56/7206	3.42067130467e-30
ko04721	Synaptic vesicle cycle	45/816	80/7206	1.05063684246e-22
ko04728	Dopaminergic synapse	70/816	185/7206	1.59726935873e-21
ko05032	Morphine addiction	52/816	110/7206	1.96879523282e-21
ko04727	GABAergic synapse	51/816	110/7206	1.44456512532e-20
ko04713	Circadian entrainment	55/816	136/7206	1.11767536789e-18
ko04723	Retrograde endocannabinoid signaling	62/816	175/7206	1.65455071065e-17
ko04725	Cholinergic synapse	58/816	160/7206	5.58791209969e-17
ko04024	cAMP signaling pathway	76/816	279/7206	5.80959490155e-14
ko04911	Insulin secretion	43/816	117/7206	3.92996873175e-13
ko04720	Long-term potentiation	38/816	99/7206	1.97083616724e-12
ko04921	Oxytocin signaling pathway	60/816	209/7206	2.60994750868e-12
ko04261	Adrenergic signaling in cardiomyocytes	58/816	205/7206	1.19060408298e-11
ko05031	Amphetamine addiction	35/816	91/7206	1.39613798873e-11
ko04020	Calcium signaling pathway	68/816	265/7206	3.14480933096e-11
ko04726	Serotonergic synapse	43/816	137/7206	1.60643007839e-10
ko04742	Taste transduction	25/816	61/7206	2.52726502263e-09
ko04744	Phototransduction	18/816	36/7206	9.77142092182e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	26/816	74/7206	5.45905587093e-08
ko05030	Cocaine addiction	25/816	73/7206	1.74846805953e-07
ko04970	Salivary secretion	29/816	95/7206	3.12094987764e-07
ko04010	MAPK signaling pathway	66/816	321/7206	8.49799780784e-07
ko03040	Spliceosome	1/816	145/7206	8.52392661322e-07
ko04925	Aldosterone synthesis and secretion	30/816	105/7206	9.5550112986e-07
ko04966	Collecting duct acid secretion	13/816	26/7206	1.16427747572e-06
ko04971	Gastric acid secretion	28/816	98/7206	2.19577124818e-06
ko04360	Axon guidance	51/816	233/7206	2.5375276766e-06
ko05203	Viral carcinogenesis	10/816	277/7206	4.28526308896e-06
ko04514	Cell adhesion molecules (CAMs)	33/816	130/7206	7.53304495647e-06
ko04730	Long-term depression	23/816	78/7206	9.92304618268e-06
ko04972	Pancreatic secretion	29/816	111/7206	1.16634957474e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/816	79/7206	1.25288289268e-05
ko04060	Cytokine-cytokine receptor interaction	5/816	191/7206	1.34419508754e-05
ko04072	Phospholipase D signaling pathway	43/816	197/7206	1.7708340641e-05
ko05164	Influenza A	4/816	167/7206	3.25517700811e-05
ko05168	Herpes simplex infection	5/816	182/7206	4.07856518061e-05
ko04070	Phosphatidylinositol signaling system	28/816	112/7206	5.47699195635e-05
ko04260	Cardiac muscle contraction	25/816	98/7206	7.05212277284e-05
ko04120	Ubiquitin mediated proteolysis	3/816	138/7206	0.00010945835608
ko04745	Phototransduction - fly	13/816	38/7206	0.000165331478151
ko04621	NOD-like receptor signaling pathway	5/816	157/7206	0.000315588503242
ko04141	Protein processing in endoplasmic reticulum	7/816	184/7206	0.000362770826185
ko04915	Estrogen signaling pathway	29/816	131/7206	0.000382992717717
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/816	14/7206	0.000389554606747
ko05414	Dilated cardiomyopathy	26/816	112/7206	0.00039697396039
ko05110	Vibrio cholerae infection	17/816	63/7206	0.00045662652173
ko04740	Olfactory transduction	20/816	80/7206	0.00051095304493
ko05322	Systemic lupus erythematosus	5/816	151/7206	0.000627438635736
ko05169	Epstein-Barr virus infection	9/816	206/7206	0.000713819450135
ko04022	cGMP-PKG signaling pathway	41/816	216/7206	0.000949793410852
ko04014	Ras signaling pathway	50/816	279/7206	0.000958215808646
ko04924	Renin secretion	20/816	86/7206	0.00156930132578
ko04612	Antigen processing and presentation	1/816	77/7206	0.00172973677839
ko03013	RNA transport	7/816	166/7206	0.00177966246332
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/816	59/7206	0.0026859766009
ko04540	Gap junction	26/816	128/7206	0.00275306099703
ko04750	Inflammatory mediator regulation of TRP channels	25/816	122/7206	0.00341007781808
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/816	182/7206	0.00414564649836
ko00240	Pyrimidine metabolism	4/816	110/7206	0.00606284437577
ko03008	Ribosome biogenesis in eukaryotes	2/816	79/7206	0.00710304391612
ko05161	Hepatitis B	9/816	173/7206	0.00725842748148
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/816	92/7206	0.00766980878434
ko04064	NF-kappa B signaling pathway	3/816	96/7206	0.00835616044048
ko04640	Hematopoietic cell lineage	1/816	64/7206	0.00846110994273
ko05162	Measles	5/816	120/7206	0.00852745144308
ko05410	Hypertrophic cardiomyopathy (HCM)	20/816	100/7206	0.0101128696813
ko05205	Proteoglycans in cancer	18/816	271/7206	0.0108812395877
ko04110	Cell cycle	7/816	145/7206	0.0110970414276
ko04146	Peroxisome	3/816	89/7206	0.0112568810952
ko04626	Plant-pathogen interaction	6/816	18/7206	0.0115877784586
ko04964	Proximal tubule bicarbonate reclamation	8/816	29/7206	0.012799198605
ko04912	GnRH signaling pathway	23/816	122/7206	0.0133380167964
ko00310	Lysine degradation	2/816	73/7206	0.014646293768
ko05140	Leishmaniasis	2/816	75/7206	0.0152814005652
ko00480	Glutathione metabolism	1/816	55/7206	0.0177849768739
ko04015	Rap1 signaling pathway	44/816	278/7206	0.02013080088
ko04114	Oocyte meiosis	25/816	139/7206	0.0203685854632
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/816	15/7206	0.020935433487
ko03018	RNA degradation	3/816	84/7206	0.0225324632412
ko04071	Sphingolipid signaling pathway	28/816	162/7206	0.0229671334638
ko00590	Arachidonic acid metabolism	1/816	52/7206	0.0261935657348
ko05323	Rheumatoid arthritis	17/816	89/7206	0.0273682947636
ko04722	Neurotrophin signaling pathway	27/816	160/7206	0.0313010252355
ko04140	Autophagy - animal	10/816	164/7206	0.0331669398074
ko04144	Endocytosis	51/816	342/7206	0.035746897693
ko04510	Focal adhesion	17/816	240/7206	0.0375116993189
ko00260	Glycine, serine and threonine metabolism	1/816	48/7206	0.0382189848175
ko05231	Choline metabolism in cancer	23/816	134/7206	0.0382353740398
ko00512	Mucin type O-glycan biosynthesis	7/816	29/7206	0.0391403979549
ko04350	TGF-beta signaling pathway	5/816	103/7206	0.0398926439164
ko05222	Small cell lung cancer	4/816	89/7206	0.0417330635913
ko00330	Arginine and proline metabolism	2/816	61/7206	0.0420866789746
ko04330	Notch signaling pathway	2/816	62/7206	0.0422811195809
ko01524	Platinum drug resistance	3/816	76/7206	0.0431390081478
ko05145	Toxoplasmosis	7/816	126/7206	0.0453227178318
ko05034	Alcoholism	37/816	238/7206	0.0471839819874
ko04976	Bile secretion	15/816	80/7206	0.0482988196954
ko05215	Prostate cancer	6/816	111/7206	0.0486478042656
ko04930	Type II diabetes mellitus	11/816	54/7206	0.048699858496