ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	59/462	145/7206	1.86170956116e-33
ko04110	Cell cycle	46/462	145/7206	6.91630151595e-21
ko03030	DNA replication	23/462	38/7206	1.34759153205e-18
ko04111	Cell cycle - yeast	33/462	90/7206	1.97031036931e-17
ko04113	Meiosis - yeast	22/462	70/7206	1.66448376092e-10
ko03013	RNA transport	34/462	166/7206	8.3960575902e-10
ko03430	Mismatch repair	12/462	22/7206	1.50471380157e-09
ko05217	Basal cell carcinoma	20/462	68/7206	4.22635080893e-09
ko03410	Base excision repair	14/462	38/7206	3.7901381004e-08
ko04144	Endocytosis	2/462	342/7206	4.75808244895e-08
ko03015	mRNA surveillance pathway	22/462	93/7206	5.85540624455e-08
ko03460	Fanconi anemia pathway	14/462	51/7206	2.33584847996e-06
ko03440	Homologous recombination	12/462	41/7206	5.97239207489e-06
ko03008	Ribosome biogenesis in eukaryotes	17/462	79/7206	7.6225640838e-06
ko00240	Pyrimidine metabolism	20/462	110/7206	1.80569625568e-05
ko03420	Nucleotide excision repair	12/462	46/7206	2.1912543065e-05
ko05166	HTLV-I infection	38/462	292/7206	2.36756938235e-05
ko04330	Notch signaling pathway	14/462	62/7206	2.73384733169e-05
ko05322	Systemic lupus erythematosus	24/462	151/7206	2.84648767083e-05
ko04310	Wnt signaling pathway	27/462	181/7206	3.47452684549e-05
ko04550	Signaling pathways regulating pluripotency of stem cells	25/462	165/7206	6.0227085899e-05
ko05168	Herpes simplex infection	26/462	182/7206	9.22567236481e-05
ko04723	Retrograde endocannabinoid signaling	1/462	175/7206	0.000224853378115
ko04062	Chemokine signaling pathway	2/462	201/7206	0.000340538899773
ko05224	Breast cancer	24/462	174/7206	0.000392407140107
ko05202	Transcriptional misregulation in cancer	25/462	188/7206	0.000418851622138
ko04725	Cholinergic synapse	1/462	160/7206	0.000470707562459
ko04022	cGMP-PKG signaling pathway	3/462	216/7206	0.000606521869753
ko04141	Protein processing in endoplasmic reticulum	2/462	184/7206	0.000685170709675
ko04921	Oxytocin signaling pathway	3/462	209/7206	0.000861497336208
ko04390	Hippo signaling pathway	24/462	188/7206	0.00121210415318
ko04371	Apelin signaling pathway	2/462	177/7206	0.00150269000012
ko05231	Choline metabolism in cancer	1/462	134/7206	0.00216826024719
ko04060	Cytokine-cytokine receptor interaction	3/462	191/7206	0.00244461196235
ko03018	RNA degradation	13/462	84/7206	0.00247213781964
ko04071	Sphingolipid signaling pathway	2/462	162/7206	0.00296398521978
ko04140	Autophagy - animal	2/462	164/7206	0.00305898124949
ko04514	Cell adhesion molecules (CAMs)	1/462	130/7206	0.00320037032383
ko04915	Estrogen signaling pathway	1/462	131/7206	0.00324100939222
ko04024	cAMP signaling pathway	7/462	279/7206	0.0038960802292
ko05160	Hepatitis C	2/462	153/7206	0.00416467397131
ko04270	Vascular smooth muscle contraction	2/462	154/7206	0.00417681909308
ko04621	NOD-like receptor signaling pathway	2/462	157/7206	0.00431527110302
ko04066	HIF-1 signaling pathway	1/462	123/7206	0.00463958272979
ko05034	Alcoholism	26/462	238/7206	0.00669578267512
ko04911	Insulin secretion	1/462	117/7206	0.00676948610827
ko04910	Insulin signaling pathway	3/462	172/7206	0.00677676537845
ko05206	MicroRNAs in cancer	21/462	177/7206	0.00722570493665
ko04218	Cellular senescence	21/462	177/7206	0.00722570493665
ko04151	PI3K-Akt signaling pathway	13/462	390/7206	0.00773989697812
ko04120	Ubiquitin mediated proteolysis	17/462	138/7206	0.00790288894617
ko04972	Pancreatic secretion	1/462	111/7206	0.00986439926476
ko04070	Phosphatidylinositol signaling system	1/462	112/7206	0.00996996275041
ko04340	Hedgehog signaling pathway	9/462	58/7206	0.0108351365544
ko04380	Osteoclast differentiation	2/462	134/7206	0.0119807839458
ko04933	AGE-RAGE signaling pathway in diabetic complications	2/462	135/7206	0.0120203378546
ko04713	Circadian entrainment	2/462	136/7206	0.0121035108335
ko04722	Neurotrophin signaling pathway	3/462	160/7206	0.013245786343
ko04261	Adrenergic signaling in cardiomyocytes	5/462	205/7206	0.0134620031236
ko01521	EGFR tyrosine kinase inhibitor resistance	1/462	106/7206	0.0145212168187
ko01200	Carbon metabolism	2/462	128/7206	0.0169639755796
ko05142	Chagas disease (American trypanosomiasis)	2/462	130/7206	0.0171816390933
ko04142	Lysosome	3/462	151/7206	0.0182035257425
ko04670	Leukocyte transendothelial migration	3/462	151/7206	0.0182035257425
ko05132	Salmonella infection	1/462	98/7206	0.02068514577
ko00564	Glycerophospholipid metabolism	1/462	99/7206	0.020856684941
ko05146	Amoebiasis	1/462	99/7206	0.020856684941
ko04620	Toll-like receptor signaling pathway	1/462	100/7206	0.0211169717918
ko04114	Oocyte meiosis	16/462	139/7206	0.0211507175488
ko05200	Pathways in cancer	44/462	492/7206	0.0217947069439
ko04668	TNF signaling pathway	2/462	120/7206	0.0239158533953
ko04912	GnRH signaling pathway	2/462	122/7206	0.0239636842671
ko04211	Longevity regulating pathway	2/462	123/7206	0.0241066175129
ko04014	Ras signaling pathway	9/462	279/7206	0.0241957350416
ko04660	T cell receptor signaling pathway	2/462	124/7206	0.0243289846084
ko04139	Mitophagy - yeast	6/462	37/7206	0.0286704705464
ko05222	Small cell lung cancer	11/462	89/7206	0.0288435588596
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/462	92/7206	0.0299759549713
ko05203	Viral carcinogenesis	27/462	277/7206	0.0321391189467
ko04728	Dopaminergic synapse	5/462	185/7206	0.0327065627617
ko05152	Tuberculosis	5/462	187/7206	0.0328928792325
ko04145	Phagosome	4/462	162/7206	0.0341509577533
ko04611	Platelet activation	4/462	163/7206	0.0342462592141
ko04530	Tight junction	7/462	228/7206	0.0378798410092
ko04924	Renin secretion	1/462	86/7206	0.0433639734474
ko04918	Thyroid hormone synthesis	1/462	86/7206	0.0433639734474
ko05133	Pertussis	1/462	87/7206	0.0438065140606
ko05323	Rheumatoid arthritis	1/462	89/7206	0.0451886161819
ko00562	Inositol phosphate metabolism	1/462	89/7206	0.0451886161819
ko04012	ErbB signaling pathway	2/462	109/7206	0.0471841003646
ko05414	Dilated cardiomyopathy	2/462	112/7206	0.0483524633081
ko04931	Insulin resistance	3/462	137/7206	0.0494638830459