ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	69/323	423/7206	3.18732560976e-22
ko04724	Glutamatergic synapse	41/323	152/7206	1.13776889116e-21
ko05033	Nicotine addiction	24/323	56/7206	2.20791622365e-18
ko04723	Retrograde endocannabinoid signaling	31/323	175/7206	2.74513295472e-11
ko04727	GABAergic synapse	23/323	110/7206	3.70856662721e-10
ko04728	Dopaminergic synapse	30/323	185/7206	5.58575579398e-10
ko04713	Circadian entrainment	24/323	136/7206	5.71720611699e-09
ko04024	cAMP signaling pathway	36/323	279/7206	6.51794890998e-09
ko04721	Synaptic vesicle cycle	18/323	80/7206	9.38452612259e-09
ko04720	Long-term potentiation	20/323	99/7206	1.01248685575e-08
ko05032	Morphine addiction	21/323	110/7206	1.24563980309e-08
ko05030	Cocaine addiction	17/323	73/7206	1.40458041598e-08
ko05031	Amphetamine addiction	18/323	91/7206	7.94833117977e-08
ko04020	Calcium signaling pathway	31/323	265/7206	7.28253120046e-07
ko04726	Serotonergic synapse	20/323	137/7206	2.57556040871e-06
ko04911	Insulin secretion	18/323	117/7206	3.85031156974e-06
ko04742	Taste transduction	12/323	61/7206	1.28750867097e-05
ko04921	Oxytocin signaling pathway	24/323	209/7206	1.88145333055e-05
ko04010	MAPK signaling pathway	32/323	321/7206	2.0018087407e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	13/323	74/7206	2.03923124801e-05
ko05203	Viral carcinogenesis	1/323	277/7206	7.55920917635e-05
ko04514	Cell adhesion molecules (CAMs)	16/323	130/7206	0.000212098370128
ko04261	Adrenergic signaling in cardiomyocytes	21/323	205/7206	0.000391959455619
ko04730	Long-term depression	11/323	78/7206	0.000651481062244
ko04970	Salivary secretion	12/323	95/7206	0.0010279741586
ko04072	Phospholipase D signaling pathway	19/323	197/7206	0.00138133211407
ko00512	Mucin type O-glycan biosynthesis	6/323	29/7206	0.0015322421554
ko05169	Epstein-Barr virus infection	1/323	206/7206	0.00163325937005
ko04014	Ras signaling pathway	24/323	279/7206	0.00178231106689
ko05231	Choline metabolism in cancer	14/323	134/7206	0.00260977626925
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	10/323	79/7206	0.00261589523099
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/323	14/7206	0.00277389513106
ko05168	Herpes simplex infection	1/323	182/7206	0.00335713837538
ko04260	Cardiac muscle contraction	11/323	98/7206	0.00423347608425
ko05200	Pathways in cancer	10/323	492/7206	0.00448558691827
ko04725	Cholinergic synapse	15/323	160/7206	0.00586668614867
ko04550	Signaling pathways regulating pluripotency of stem cells	1/323	165/7206	0.00709254623463
ko05164	Influenza A	1/323	167/7206	0.00712527860955
ko04621	NOD-like receptor signaling pathway	1/323	157/7206	0.0102961252479
ko04940	Type I diabetes mellitus	5/323	32/7206	0.0130346795176
ko05410	Hypertrophic cardiomyopathy (HCM)	10/323	100/7206	0.0137681825341
ko05166	HTLV-I infection	5/323	292/7206	0.0138228486296
ko04972	Pancreatic secretion	11/323	111/7206	0.0166054257278
ko04070	Phosphatidylinositol signaling system	11/323	112/7206	0.0170422012856
ko05414	Dilated cardiomyopathy	11/323	112/7206	0.0170422012856
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/323	182/7206	0.0176335600464
ko03040	Spliceosome	1/323	145/7206	0.0225671595428
ko05034	Alcoholism	18/323	238/7206	0.0253236088803
ko04022	cGMP-PKG signaling pathway	17/323	216/7206	0.0275272875467
ko04151	PI3K-Akt signaling pathway	9/323	390/7206	0.0315918476795
ko05205	Proteoglycans in cancer	5/323	271/7206	0.0342569836514
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	4/323	28/7206	0.0346846708404
ko04611	Platelet activation	2/323	163/7206	0.0347843706445
ko04140	Autophagy - animal	2/323	164/7206	0.0347919827157
ko00513	Various types of N-glycan biosynthesis	5/323	42/7206	0.0383586989369
ko04668	TNF signaling pathway	1/323	120/7206	0.0445596026507
ko02025	Biofilm formation - Pseudomonas aeruginosa	1/323	1/7206	0.0448237579796
ko05145	Toxoplasmosis	1/323	126/7206	0.0460794426585
ko05202	Transcriptional misregulation in cancer	3/323	188/7206	0.0489045975113