ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko01200	Carbon metabolism	42/489	128/7206	7.72766278436e-19
ko00071	Fatty acid degradation	18/489	45/7206	2.11052250488e-10
ko04260	Cardiac muscle contraction	26/489	98/7206	8.36814311529e-10
ko00380	Tryptophan metabolism	18/489	50/7206	1.61284643846e-09
ko00020	Citrate cycle (TCA cycle)	15/489	35/7206	2.21145054874e-09
ko00710	Carbon fixation in photosynthetic organisms	13/489	27/7206	4.60354304449e-09
ko00010	Glycolysis / Gluconeogenesis	21/489	74/7206	9.79304935139e-09
ko00190	Oxidative phosphorylation	28/489	127/7206	1.70771446998e-08
ko05010	Alzheimer's disease	37/489	202/7206	1.8400784389e-08
ko00620	Pyruvate metabolism	16/489	46/7206	2.34596076355e-08
ko05012	Parkinson's disease	31/489	155/7206	3.33847327876e-08
ko04610	Complement and coagulation cascades	21/489	79/7206	3.49622730159e-08
ko04974	Protein digestion and absorption	23/489	96/7206	6.49573457812e-08
ko00640	Propanoate metabolism	13/489	34/7206	1.3687474097e-07
ko00360	Phenylalanine metabolism	9/489	17/7206	4.22348988426e-07
ko00350	Tyrosine metabolism	12/489	33/7206	7.94221053983e-07
ko05034	Alcoholism	1/489	238/7206	1.27051806808e-06
ko00500	Starch and sucrose metabolism	12/489	35/7206	1.64755591453e-06
ko01230	Biosynthesis of amino acids	19/489	85/7206	2.82622496444e-06
ko01212	Fatty acid metabolism	15/489	60/7206	7.41465999963e-06
ko00362	Benzoate degradation	5/489	6/7206	7.9962336422e-06
ko05410	Hypertrophic cardiomyopathy (HCM)	20/489	100/7206	9.47195321423e-06
ko00280	Valine, leucine and isoleucine degradation	14/489	54/7206	9.48112159634e-06
ko03320	PPAR signaling pathway	16/489	69/7206	1.04964374812e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	29/489	182/7206	1.44335789703e-05
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	4/489	4/7206	2.0964212333e-05
ko00643	Styrene degradation	4/489	4/7206	2.0964212333e-05
ko00120	Primary bile acid biosynthesis	8/489	20/7206	2.58223850727e-05
ko00330	Arginine and proline metabolism	14/489	61/7206	4.23136207538e-05
ko05016	Huntington's disease	31/489	215/7206	4.99940273455e-05
ko00680	Methane metabolism	10/489	34/7206	5.61274194792e-05
ko00260	Glycine, serine and threonine metabolism	12/489	48/7206	6.09855361125e-05
ko00140	Steroid hormone biosynthesis	11/489	41/7206	6.12855722379e-05
ko04146	Peroxisome	17/489	89/7206	8.121394173e-05
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	4/489	5/7206	9.91739397656e-05
ko04080	Neuroactive ligand-receptor interaction	11/489	423/7206	0.000132055363966
ko00630	Glyoxylate and dicarboxylate metabolism	10/489	38/7206	0.000158133366179
ko05414	Dilated cardiomyopathy	19/489	112/7206	0.0001669765979
ko00030	Pentose phosphate pathway	9/489	32/7206	0.000194139284897
ko00980	Metabolism of xenobiotics by cytochrome P450	10/489	40/7206	0.000250719168415
ko00950	Isoquinoline alkaloid biosynthesis	5/489	10/7206	0.000266940732648
ko05204	Chemical carcinogenesis	11/489	48/7206	0.00028401913124
ko00830	Retinol metabolism	10/489	42/7206	0.000384886729305
ko04142	Lysosome	1/489	151/7206	0.000462185787656
ko04922	Glucagon signaling pathway	20/489	128/7206	0.000469308654767
ko05150	Staphylococcus aureus infection	9/489	36/7206	0.000510612292346
ko04015	Rap1 signaling pathway	6/489	278/7206	0.000593094451629
ko03040	Spliceosome	1/489	145/7206	0.000678845137128
ko00250	Alanine, aspartate and glutamate metabolism	9/489	38/7206	0.000782870096412
ko04144	Endocytosis	9/489	342/7206	0.000844014239876
ko05203	Viral carcinogenesis	6/489	277/7206	0.00085422838334
ko04261	Adrenergic signaling in cardiomyocytes	27/489	205/7206	0.000955711974
ko04120	Ubiquitin mediated proteolysis	1/489	138/7206	0.000996649941894
ko00310	Lysine degradation	13/489	73/7206	0.00110322999859
ko00040	Pentose and glucuronate interconversions	7/489	26/7206	0.00134299638042
ko00051	Fructose and mannose metabolism	9/489	42/7206	0.00167990200343
ko00410	beta-Alanine metabolism	8/489	35/7206	0.00195166286117
ko04014	Ras signaling pathway	7/489	279/7206	0.00215428196827
ko03010	Ribosome	1/489	129/7206	0.00216568070996
ko04976	Bile secretion	13/489	80/7206	0.00260868782474
ko00053	Ascorbate and aldarate metabolism	6/489	22/7206	0.00276964067697
ko00281	Geraniol degradation	3/489	5/7206	0.00280111081957
ko00982	Drug metabolism - cytochrome P450	8/489	37/7206	0.00284021517064
ko05200	Pathways in cancer	18/489	492/7206	0.00285392569802
ko00561	Glycerolipid metabolism	11/489	63/7206	0.0030721443424
ko04022	cGMP-PKG signaling pathway	26/489	216/7206	0.0036534132142
ko04152	AMPK signaling pathway	21/489	161/7206	0.00367298196854
ko04062	Chemokine signaling pathway	4/489	201/7206	0.00388018915053
ko00720	Carbon fixation pathways in prokaryotes	5/489	17/7206	0.00440275916918
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	4/489	11/7206	0.00470797364513
ko04270	Vascular smooth muscle contraction	20/489	154/7206	0.00501233987088
ko04060	Cytokine-cytokine receptor interaction	4/489	191/7206	0.00515799479929
ko01040	Biosynthesis of unsaturated fatty acids	6/489	25/7206	0.00552582124526
ko00052	Galactose metabolism	7/489	33/7206	0.0057704878696
ko04114	Oocyte meiosis	2/489	139/7206	0.0058733287162
ko05032	Morphine addiction	1/489	110/7206	0.00666329072571
ko00650	Butanoate metabolism	6/489	26/7206	0.00678066870474
ko03013	RNA transport	3/489	166/7206	0.00697818678781
ko04390	Hippo signaling pathway	4/489	188/7206	0.00732920262133
ko04975	Fat digestion and absorption	7/489	35/7206	0.00807719553992
ko04722	Neurotrophin signaling pathway	3/489	160/7206	0.00975499276782
ko05206	MicroRNAs in cancer	4/489	177/7206	0.00978335269735
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/489	79/7206	0.0103307168819
ko04512	ECM-receptor interaction	12/489	79/7206	0.0103307168819
ko05416	Viral myocarditis	9/489	55/7206	0.0109454304839
ko00270	Cysteine and methionine metabolism	8/489	47/7206	0.0127591140416
ko04650	Natural killer cell mediated cytotoxicity	1/489	97/7206	0.0140630110743
ko04720	Long-term potentiation	1/489	99/7206	0.0141736630975
ko04620	Toll-like receptor signaling pathway	1/489	100/7206	0.0143355426223
ko04978	Mineral absorption	7/489	40/7206	0.0167210697305
ko04550	Signaling pathways regulating pluripotency of stem cells	4/489	165/7206	0.0183450473416
ko04920	Adipocytokine signaling pathway	12/489	89/7206	0.0183523140577
ko00930	Caprolactam degradation	3/489	9/7206	0.0191661518433
ko00220	Arginine biosynthesis	5/489	24/7206	0.0204201346443
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/489	92/7206	0.0204215658412
ko00983	Drug metabolism - other enzymes	7/489	42/7206	0.0215399403403
ko00062	Fatty acid elongation	6/489	33/7206	0.0218332724221
ko04013	MAPK signaling pathway - fly	2/489	115/7206	0.023725897932
ko00340	Histidine metabolism	5/489	25/7206	0.024143712994
ko04141	Protein processing in endoplasmic reticulum	5/489	184/7206	0.0245573244967
ko04728	Dopaminergic synapse	5/489	185/7206	0.0247755486867
ko04726	Serotonergic synapse	3/489	137/7206	0.024970021073
ko05323	Rheumatoid arthritis	1/489	89/7206	0.0304789123995
ko04111	Cell cycle - yeast	1/489	90/7206	0.0310593439577
ko05215	Prostate cancer	2/489	111/7206	0.0338861735223
ko04724	Glutamatergic synapse	4/489	152/7206	0.0338923630105
ko04360	Axon guidance	8/489	233/7206	0.0341129849173
ko00232	Caffeine metabolism	2/489	5/7206	0.0400567702608
ko01210	2-Oxocarboxylic acid metabolism	4/489	20/7206	0.0425671151431
ko04721	Synaptic vesicle cycle	1/489	80/7206	0.0426907153989
ko04964	Proximal tubule bicarbonate reclamation	5/489	29/7206	0.0432494237411
ko02010	ABC transporters	6/489	39/7206	0.0457614623195
ko04350	TGF-beta signaling pathway	2/489	103/7206	0.04684230552
ko04914	Progesterone-mediated oocyte maturation	2/489	104/7206	0.047114228927
ko04540	Gap junction	3/489	128/7206	0.0482538419315
ko05169	Epstein-Barr virus infection	7/489	206/7206	0.0485530990016
ko00100	Steroid biosynthesis	4/489	21/7206	0.0498628364753