ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	99/579	423/7206	4.83332257211e-24
ko04724	Glutamatergic synapse	55/579	152/7206	3.80582645406e-23
ko05033	Nicotine addiction	32/579	56/7206	2.80711189037e-21
ko04721	Synaptic vesicle cycle	37/579	80/7206	3.30163456718e-20
ko04728	Dopaminergic synapse	55/579	185/7206	1.46638117644e-18
ko04713	Circadian entrainment	42/579	136/7206	4.587975073e-15
ko04727	GABAergic synapse	37/579	110/7206	9.88898406517e-15
ko04723	Retrograde endocannabinoid signaling	47/579	175/7206	3.90438335086e-14
ko05032	Morphine addiction	36/579	110/7206	6.01605233239e-14
ko04024	cAMP signaling pathway	56/579	279/7206	6.21240091796e-11
ko04911	Insulin secretion	33/579	117/7206	6.69414964229e-11
ko04725	Cholinergic synapse	38/579	160/7206	6.1291257607e-10
ko05031	Amphetamine addiction	27/579	91/7206	1.0874597279e-09
ko04726	Serotonergic synapse	34/579	137/7206	1.47032378891e-09
ko04921	Oxytocin signaling pathway	44/579	209/7206	1.64420092758e-09
ko04261	Adrenergic signaling in cardiomyocytes	43/579	205/7206	2.86052250097e-09
ko05030	Cocaine addiction	22/579	73/7206	2.83122671718e-08
ko04720	Long-term potentiation	25/579	99/7206	1.57638089597e-07
ko04020	Calcium signaling pathway	45/579	265/7206	1.29788888464e-06
ko04970	Salivary secretion	22/579	95/7206	4.19280099645e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	18/579	74/7206	1.52368671934e-05
ko04966	Collecting duct acid secretion	10/579	26/7206	1.68939817027e-05
ko04010	MAPK signaling pathway	48/579	321/7206	2.04119935571e-05
ko04260	Cardiac muscle contraction	21/579	98/7206	2.47292644224e-05
ko05203	Viral carcinogenesis	6/579	277/7206	3.96298941335e-05
ko04514	Cell adhesion molecules (CAMs)	25/579	130/7206	4.76524579045e-05
ko04742	Taste transduction	15/579	61/7206	6.79914218987e-05
ko04744	Phototransduction	11/579	36/7206	7.66544675557e-05
ko04022	cGMP-PKG signaling pathway	34/579	216/7206	0.000114154597197
ko04730	Long-term depression	17/579	78/7206	0.000116335744452
ko03040	Spliceosome	1/579	145/7206	0.00014018571007
ko04630	Jak-STAT signaling pathway	1/579	132/7206	0.000293638172822
ko05110	Vibrio cholerae infection	14/579	63/7206	0.000371638354896
ko04972	Pancreatic secretion	20/579	111/7206	0.000550707636461
ko05322	Systemic lupus erythematosus	2/579	151/7206	0.00066761376312
ko05164	Influenza A	3/579	167/7206	0.000805804536168
ko05010	Alzheimer's disease	30/579	202/7206	0.000888638750869
ko05162	Measles	1/579	120/7206	0.000970562844397
ko04072	Phospholipase D signaling pathway	29/579	197/7206	0.0012504851764
ko05168	Herpes simplex infection	4/579	182/7206	0.00131334814458
ko04120	Ubiquitin mediated proteolysis	2/579	138/7206	0.00132844678679
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/579	79/7206	0.00134256370724
ko04925	Aldosterone synthesis and secretion	18/579	105/7206	0.00174190864874
ko04626	Plant-pathogen interaction	6/579	18/7206	0.00210420524325
ko04971	Gastric acid secretion	17/579	98/7206	0.00212865215695
ko04070	Phosphatidylinositol signaling system	19/579	112/7206	0.00222020045038
ko04745	Phototransduction - fly	9/579	38/7206	0.00257512055581
ko04060	Cytokine-cytokine receptor interaction	5/579	191/7206	0.00271950429735
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/579	92/7206	0.00287930467341
ko05034	Alcoholism	32/579	238/7206	0.00338423034797
ko03013	RNA transport	4/579	166/7206	0.00356477187066
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/579	14/7206	0.0035728546593
ko04141	Protein processing in endoplasmic reticulum	5/579	184/7206	0.00372984589348
ko05169	Epstein-Barr virus infection	6/579	206/7206	0.00382861713187
ko04924	Renin secretion	15/579	86/7206	0.0039251628616
ko04540	Gap junction	20/579	128/7206	0.00439595399396
ko04915	Estrogen signaling pathway	20/579	131/7206	0.0050055928006
ko05205	Proteoglycans in cancer	10/579	271/7206	0.00583928902467
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/579	59/7206	0.00657121114979
ko04964	Proximal tubule bicarbonate reclamation	7/579	29/7206	0.00682361798313
ko04621	NOD-like receptor signaling pathway	4/579	157/7206	0.00689979299218
ko04611	Platelet activation	5/579	163/7206	0.0129382804012
ko04140	Autophagy - animal	5/579	164/7206	0.012946074155
ko05323	Rheumatoid arthritis	14/579	89/7206	0.0158532303301
ko04211	Longevity regulating pathway	3/579	123/7206	0.0177151635833
ko04612	Antigen processing and presentation	1/579	77/7206	0.0196998306751
ko05166	HTLV-I infection	13/579	292/7206	0.0203781202255
ko04510	Focal adhesion	10/579	240/7206	0.0214261741067
ko05161	Hepatitis B	6/579	173/7206	0.0225662050301
ko04064	NF-kappa B signaling pathway	2/579	96/7206	0.0229489859379
ko04014	Ras signaling pathway	33/579	279/7206	0.0239031129997
ko04145	Phagosome	21/579	162/7206	0.0271155966811
ko04360	Axon guidance	28/579	233/7206	0.0273468521708
ko00310	Lysine degradation	1/579	73/7206	0.0286930372886
ko04068	FoxO signaling pathway	6/579	167/7206	0.0298929750219
ko01524	Platinum drug resistance	1/579	76/7206	0.0300954561616
ko05215	Prostate cancer	3/579	111/7206	0.0335268375656
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/579	182/7206	0.0368638046272
ko04978	Mineral absorption	7/579	40/7206	0.0379703196867
ko04110	Cell cycle	5/579	145/7206	0.0429197385248
ko04213	Longevity regulating pathway - multiple species	2/579	86/7206	0.0455114670939
ko04146	Peroxisome	2/579	89/7206	0.0465188140355
ko05222	Small cell lung cancer	2/579	89/7206	0.0465188140355
ko05200	Pathways in cancer	28/579	492/7206	0.0479383070457
ko04217	Necroptosis	7/579	178/7206	0.0487253693503