ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	58/454	145/7206	7.83039772442e-33
ko04110	Cell cycle	56/454	145/7206	9.34880939884e-31
ko03030	DNA replication	28/454	38/7206	2.8450085869e-26
ko04111	Cell cycle - yeast	39/454	90/7206	7.43744422039e-24
ko03013	RNA transport	50/454	166/7206	7.55475955393e-22
ko03440	Homologous recombination	24/454	41/7206	4.74384311476e-19
ko03460	Fanconi anemia pathway	26/454	51/7206	1.7309817175e-18
ko04113	Meiosis - yeast	26/454	70/7206	2.53253381836e-14
ko03410	Base excision repair	19/454	38/7206	1.23633653672e-13
ko03008	Ribosome biogenesis in eukaryotes	26/454	79/7206	6.90137571477e-13
ko03430	Mismatch repair	14/454	22/7206	2.56620606007e-12
ko00240	Pyrimidine metabolism	28/454	110/7206	9.32143632064e-11
ko03420	Nucleotide excision repair	17/454	46/7206	9.21944556703e-10
ko04144	Endocytosis	1/454	342/7206	7.23420379506e-09
ko03015	mRNA surveillance pathway	22/454	93/7206	4.27943597904e-08
ko04218	Cellular senescence	28/454	177/7206	4.83327661552e-06
ko05010	Alzheimer's disease	1/454	202/7206	4.67460114348e-05
ko04114	Oocyte meiosis	20/454	139/7206	0.000516622715836
ko04024	cAMP signaling pathway	5/454	279/7206	0.000576485897367
ko04115	p53 signaling pathway	13/454	74/7206	0.000629845877156
ko03018	RNA degradation	14/454	84/7206	0.00068390575873
ko04621	NOD-like receptor signaling pathway	1/454	157/7206	0.000696759890264
ko04914	Progesterone-mediated oocyte maturation	16/454	104/7206	0.000726536677255
ko04022	cGMP-PKG signaling pathway	3/454	216/7206	0.000881672738343
ko04724	Glutamatergic synapse	1/454	152/7206	0.00103649978223
ko04270	Vascular smooth muscle contraction	1/454	154/7206	0.00107711687847
ko04810	Regulation of actin cytoskeleton	5/454	264/7206	0.00109454990668
ko00230	Purine metabolism	24/454	194/7206	0.0013636905782
ko04723	Retrograde endocannabinoid signaling	2/454	175/7206	0.00142402492671
ko05168	Herpes simplex infection	23/454	182/7206	0.00158220471739
ko05166	HTLV-I infection	32/454	292/7206	0.00190892310027
ko04713	Circadian entrainment	1/454	136/7206	0.00217874304365
ko05152	Tuberculosis	3/454	187/7206	0.00344591500954
ko05012	Parkinson's disease	2/454	155/7206	0.00418063384294
ko04014	Ras signaling pathway	7/454	279/7206	0.00528500463043
ko04142	Lysosome	2/454	151/7206	0.00600292206671
ko04072	Phospholipase D signaling pathway	4/454	197/7206	0.00720030699766
ko05203	Viral carcinogenesis	29/454	277/7206	0.00743884633192
ko05222	Small cell lung cancer	12/454	89/7206	0.0124860601982
ko05169	Epstein-Barr virus infection	22/454	206/7206	0.0129283143713
ko04360	Axon guidance	6/454	233/7206	0.0130962168815
ko04659	Th17 cell differentiation	1/454	106/7206	0.0143082066157
ko04727	GABAergic synapse	1/454	110/7206	0.0151268457431
ko05032	Morphine addiction	1/454	110/7206	0.0151268457431
ko04261	Adrenergic signaling in cardiomyocytes	5/454	205/7206	0.018451732543
ko03022	Basal transcription factors	7/454	44/7206	0.018946212091
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/454	182/7206	0.0189712399112
ko04120	Ubiquitin mediated proteolysis	16/454	138/7206	0.0191211049781
ko04971	Gastric acid secretion	1/454	98/7206	0.0206546699035
ko05146	Amoebiasis	1/454	99/7206	0.0206754379336
ko05206	MicroRNAs in cancer	19/454	177/7206	0.0263202385349
ko04139	Mitophagy - yeast	6/454	37/7206	0.0265857499098
ko04510	Focal adhesion	7/454	240/7206	0.0292231811814
ko05219	Bladder cancer	7/454	48/7206	0.0293699764839
ko04015	Rap1 signaling pathway	9/454	278/7206	0.0314074819897
ko03020	RNA polymerase	5/454	29/7206	0.0328631902196
ko04668	TNF signaling pathway	2/454	120/7206	0.0344018006581
ko04750	Inflammatory mediator regulation of TRP channels	2/454	122/7206	0.0353759885428
ko04666	Fc gamma R-mediated phagocytosis	2/454	122/7206	0.0353759885428
ko05212	Pancreatic cancer	10/454	83/7206	0.0392273252192
ko04921	Oxytocin signaling pathway	6/454	209/7206	0.0413373246924
ko04924	Renin secretion	1/454	86/7206	0.0431138588076
ko04918	Thyroid hormone synthesis	1/454	86/7206	0.0431138588076
ko04146	Peroxisome	1/454	89/7206	0.0441666639228
ko04920	Adipocytokine signaling pathway	1/454	89/7206	0.0441666639228
ko04728	Dopaminergic synapse	5/454	185/7206	0.0443067014747
ko05031	Amphetamine addiction	1/454	91/7206	0.0456694160078
ko04725	Cholinergic synapse	4/454	160/7206	0.0464951340802
ko04145	Phagosome	4/454	162/7206	0.0471883054337
ko04972	Pancreatic secretion	2/454	111/7206	0.0472988173296
ko04380	Osteoclast differentiation	3/454	134/7206	0.0476374262598
ko04931	Insulin resistance	3/454	137/7206	0.0482993852122
ko04726	Serotonergic synapse	3/454	137/7206	0.0482993852122