ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	197/1222	423/7206	7.88341554301e-49
ko04724	Glutamatergic synapse	89/1222	152/7206	1.32716331739e-31
ko05033	Nicotine addiction	49/1222	56/7206	5.24647224174e-31
ko05032	Morphine addiction	70/1222	110/7206	3.31500552327e-28
ko04713	Circadian entrainment	74/1222	136/7206	1.07373945974e-23
ko04727	GABAergic synapse	65/1222	110/7206	1.21535014714e-23
ko04721	Synaptic vesicle cycle	50/1222	80/7206	5.84760413627e-20
ko04728	Dopaminergic synapse	83/1222	185/7206	2.39507292803e-19
ko04725	Cholinergic synapse	75/1222	160/7206	6.07201867628e-19
ko04723	Retrograde endocannabinoid signaling	77/1222	175/7206	2.01560857853e-17
ko04024	cAMP signaling pathway	105/1222	279/7206	3.10121242421e-17
ko04744	Phototransduction	28/1222	36/7206	1.52349234417e-15
ko04020	Calcium signaling pathway	96/1222	265/7206	1.81402828233e-14
ko04742	Taste transduction	36/1222	61/7206	1.28547449489e-13
ko04911	Insulin secretion	53/1222	117/7206	5.47440907567e-13
ko04726	Serotonergic synapse	58/1222	137/7206	1.51572334019e-12
ko04921	Oxytocin signaling pathway	75/1222	209/7206	2.83621797255e-11
ko03040	Spliceosome	1/1222	145/7206	7.14905702288e-11
ko04261	Adrenergic signaling in cardiomyocytes	72/1222	205/7206	1.62469915667e-10
ko05031	Amphetamine addiction	40/1222	91/7206	1.21454646905e-09
ko04720	Long-term potentiation	41/1222	99/7206	6.51762577567e-09
ko05203	Viral carcinogenesis	16/1222	277/7206	2.8085133101e-08
ko04360	Axon guidance	72/1222	233/7206	1.02967818287e-07
ko04970	Salivary secretion	37/1222	95/7206	2.56619088793e-07
ko03013	RNA transport	7/1222	166/7206	5.73725251165e-07
ko04070	Phosphatidylinositol signaling system	41/1222	112/7206	6.14915510941e-07
ko04740	Olfactory transduction	32/1222	80/7206	1.08602969124e-06
ko05322	Systemic lupus erythematosus	6/1222	151/7206	1.48895804204e-06
ko04925	Aldosterone synthesis and secretion	38/1222	105/7206	2.18244701561e-06
ko04022	cGMP-PKG signaling pathway	64/1222	216/7206	3.06291469768e-06
ko05030	Cocaine addiction	29/1222	73/7206	4.16010300673e-06
ko05168	Herpes simplex infection	10/1222	182/7206	4.86568148542e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	29/1222	74/7206	5.08983869368e-06
ko04060	Cytokine-cytokine receptor interaction	12/1222	191/7206	1.39660191515e-05
ko04971	Gastric acid secretion	34/1222	98/7206	1.71241494111e-05
ko04966	Collecting duct acid secretion	14/1222	26/7206	1.92579674058e-05
ko04072	Phospholipase D signaling pathway	57/1222	197/7206	2.77665510923e-05
ko04621	NOD-like receptor signaling pathway	9/1222	157/7206	3.51734745711e-05
ko05164	Influenza A	10/1222	167/7206	3.7073080484e-05
ko04745	Phototransduction - fly	17/1222	38/7206	5.69441181139e-05
ko05205	Proteoglycans in cancer	23/1222	271/7206	6.60777240096e-05
ko04610	Complement and coagulation cascades	2/1222	79/7206	0.000110637009442
ko03008	Ribosome biogenesis in eukaryotes	2/1222	79/7206	0.000110637009442
ko04924	Renin secretion	29/1222	86/7206	0.000128627341701
ko04972	Pancreatic secretion	35/1222	111/7206	0.00016559680715
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1222	79/7206	0.000203713815076
ko04514	Cell adhesion molecules (CAMs)	39/1222	130/7206	0.000209191370932
ko04010	MAPK signaling pathway	80/1222	321/7206	0.000239557058602
ko05140	Leishmaniasis	2/1222	75/7206	0.000258638232064
ko04141	Protein processing in endoplasmic reticulum	14/1222	184/7206	0.000300688502884
ko04923	Regulation of lipolysis in adipocytes	26/1222	77/7206	0.000320549265139
ko04730	Long-term depression	26/1222	78/7206	0.000371722150902
ko05169	Epstein-Barr virus infection	17/1222	206/7206	0.000440760680157
ko05110	Vibrio cholerae infection	22/1222	63/7206	0.000527101457606
ko05414	Dilated cardiomyopathy	33/1222	112/7206	0.000863068937686
ko04064	NF-kappa B signaling pathway	5/1222	96/7206	0.000873206310787
ko04626	Plant-pathogen interaction	9/1222	18/7206	0.00126642518171
ko05162	Measles	8/1222	120/7206	0.00129285453018
ko00562	Inositol phosphate metabolism	27/1222	89/7206	0.00156628923472
ko04110	Cell cycle	11/1222	145/7206	0.00158012811985
ko04260	Cardiac muscle contraction	29/1222	98/7206	0.00164780909019
ko04540	Gap junction	36/1222	128/7206	0.00178162318355
ko00240	Pyrimidine metabolism	7/1222	110/7206	0.00185922976641
ko04014	Ras signaling pathway	67/1222	279/7206	0.00195594783124
ko05161	Hepatitis B	15/1222	173/7206	0.00202580308258
ko04915	Estrogen signaling pathway	36/1222	131/7206	0.00212262606361
ko04146	Peroxisome	5/1222	89/7206	0.00248934631105
ko04120	Ubiquitin mediated proteolysis	11/1222	138/7206	0.00279476839892
ko04612	Antigen processing and presentation	4/1222	77/7206	0.00332197010592
ko04710	Circadian rhythm	15/1222	43/7206	0.00372668022675
ko04976	Bile secretion	24/1222	80/7206	0.00385721857163
ko03022	Basal transcription factors	1/1222	44/7206	0.00428199007828
ko05144	Malaria	1/1222	45/7206	0.00433673848619
ko00071	Fatty acid degradation	1/1222	45/7206	0.00433673848619
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1222	14/7206	0.00450377005832
ko03420	Nucleotide excision repair	1/1222	46/7206	0.00457352694884
ko04750	Inflammatory mediator regulation of TRP channels	33/1222	122/7206	0.00477570773134
ko04964	Proximal tubule bicarbonate reclamation	11/1222	29/7206	0.00564997104949
ko00480	Glutathione metabolism	2/1222	55/7206	0.00574922714931
ko04371	Apelin signaling pathway	44/1222	177/7206	0.00612193815538
ko04622	RIG-I-like receptor signaling pathway	3/1222	62/7206	0.00628540046017
ko04640	Hematopoietic cell lineage	3/1222	64/7206	0.00647785462359
ko04214	Apoptosis - fly	4/1222	72/7206	0.00667196028389
ko00590	Arachidonic acid metabolism	2/1222	52/7206	0.00822968020036
ko04510	Focal adhesion	26/1222	240/7206	0.00856013917102
ko04658	Th1 and Th2 cell differentiation	7/1222	96/7206	0.0087617644598
ko00330	Arginine and proline metabolism	3/1222	61/7206	0.00912402588394
ko04657	IL-17 signaling pathway	6/1222	87/7206	0.00914717473924
ko05133	Pertussis	6/1222	87/7206	0.00914717473924
ko04930	Type II diabetes mellitus	17/1222	54/7206	0.00932030488321
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1222	40/7206	0.0097720620862
ko03018	RNA degradation	6/1222	84/7206	0.0125000489158
ko04711	Circadian rhythm - fly	6/1222	13/7206	0.0136928812648
ko05231	Choline metabolism in cancer	34/1222	134/7206	0.0140086625471
ko00982	Drug metabolism - cytochrome P450	1/1222	37/7206	0.0145226020033
ko00630	Glyoxylate and dicarboxylate metabolism	1/1222	38/7206	0.0148890678813
ko05131	Shigellosis	6/1222	82/7206	0.0171013066926
ko04115	p53 signaling pathway	5/1222	74/7206	0.0182379489053
ko05321	Inflammatory bowel disease (IBD)	3/1222	56/7206	0.0185607619762
ko05166	HTLV-I infection	35/1222	292/7206	0.0207129335605
ko05016	Huntington's disease	24/1222	215/7206	0.0207876297435
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1222	100/7206	0.0216161659201
ko05145	Toxoplasmosis	12/1222	126/7206	0.0226162365029
ko04630	Jak-STAT signaling pathway	13/1222	132/7206	0.0259332940571
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/1222	15/7206	0.0294927351554
ko04922	Glucagon signaling pathway	31/1222	128/7206	0.0321316166037
ko03320	PPAR signaling pathway	5/1222	69/7206	0.0343167393472
ko04210	Apoptosis	20/1222	180/7206	0.0343308922976
ko00380	Tryptophan metabolism	3/1222	50/7206	0.0365939772809
ko00310	Lysine degradation	6/1222	73/7206	0.042112288206
ko04722	Neurotrophin signaling pathway	37/1222	160/7206	0.0423864417833
ko04062	Chemokine signaling pathway	45/1222	201/7206	0.0447537251768
ko05320	Autoimmune thyroid disease	1/1222	29/7206	0.0484582553374
ko05120	Epithelial cell signaling in Helicobacter pylori infection	23/1222	92/7206	0.0489934065083