ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	160/1056	423/7206	3.2965304834e-34
ko05033	Nicotine addiction	40/1056	56/7206	8.82741934116e-22
ko04724	Glutamatergic synapse	69/1056	152/7206	3.88484491961e-20
ko04020	Calcium signaling pathway	96/1056	265/7206	7.33972862168e-19
ko05032	Morphine addiction	49/1056	110/7206	3.05485036782e-14
ko04713	Circadian entrainment	55/1056	136/7206	1.18299771453e-13
ko04727	GABAergic synapse	45/1056	110/7206	1.31718346288e-11
ko04024	cAMP signaling pathway	84/1056	279/7206	1.69891099876e-11
ko04723	Retrograde endocannabinoid signaling	59/1056	175/7206	1.41953802633e-10
ko04725	Cholinergic synapse	54/1056	160/7206	9.35867166538e-10
ko04911	Insulin secretion	43/1056	117/7206	2.11841237965e-09
ko04742	Taste transduction	28/1056	61/7206	4.63354116212e-09
ko04728	Dopaminergic synapse	58/1056	185/7206	4.87382207053e-09
ko04721	Synaptic vesicle cycle	33/1056	80/7206	5.67099154626e-09
ko05322	Systemic lupus erythematosus	2/1056	151/7206	1.81732888892e-08
ko03010	Ribosome	1/1056	129/7206	4.51294508583e-08
ko04726	Serotonergic synapse	45/1056	137/7206	5.67503277017e-08
ko03040	Spliceosome	2/1056	145/7206	6.7997583342e-08
ko04022	cGMP-PKG signaling pathway	62/1056	216/7206	7.16500097315e-08
ko04921	Oxytocin signaling pathway	60/1056	209/7206	1.350095293e-07
ko03013	RNA transport	4/1056	166/7206	1.66951002777e-07
ko04970	Salivary secretion	34/1056	95/7206	2.17783154812e-07
ko05031	Amphetamine addiction	31/1056	91/7206	3.01650194561e-06
ko04261	Adrenergic signaling in cardiomyocytes	54/1056	205/7206	8.35319967747e-06
ko05203	Viral carcinogenesis	17/1056	277/7206	1.19970360452e-05
ko04971	Gastric acid secretion	31/1056	98/7206	1.71350636567e-05
ko04925	Aldosterone synthesis and secretion	32/1056	105/7206	3.39724387361e-05
ko04070	Phosphatidylinositol signaling system	33/1056	112/7206	6.32255963818e-05
ko04720	Long-term potentiation	30/1056	99/7206	7.1485506925e-05
ko04710	Circadian rhythm	16/1056	43/7206	0.000215147937813
ko05164	Influenza A	9/1056	167/7206	0.000221536582255
ko04730	Long-term depression	24/1056	78/7206	0.000267658544316
ko04972	Pancreatic secretion	31/1056	111/7206	0.000336313016763
ko05014	Amyotrophic lateral sclerosis (ALS)	23/1056	74/7206	0.00034411923031
ko04360	Axon guidance	54/1056	233/7206	0.000445494662525
ko04120	Ubiquitin mediated proteolysis	7/1056	138/7206	0.000570647143361
ko04514	Cell adhesion molecules (CAMs)	34/1056	130/7206	0.000603095907749
ko04110	Cell cycle	8/1056	145/7206	0.000791653855147
ko05168	Herpes simplex infection	12/1056	182/7206	0.000934233218637
ko04072	Phospholipase D signaling pathway	46/1056	197/7206	0.000989262566523
ko04270	Vascular smooth muscle contraction	38/1056	154/7206	0.00110615233445
ko05133	Pertussis	3/1056	87/7206	0.00114947511084
ko04744	Phototransduction	13/1056	36/7206	0.00115545512495
ko05169	Epstein-Barr virus infection	15/1056	206/7206	0.00133181594007
ko04930	Type II diabetes mellitus	17/1056	54/7206	0.0014738460978
ko00280	Valine, leucine and isoleucine degradation	1/1056	54/7206	0.00321092276242
ko05030	Cocaine addiction	20/1056	73/7206	0.00412326936655
ko04141	Protein processing in endoplasmic reticulum	14/1056	184/7206	0.00424544057002
ko04960	Aldosterone-regulated sodium reabsorption	13/1056	41/7206	0.00582798683455
ko04976	Bile secretion	21/1056	80/7206	0.00615391331358
ko05161	Hepatitis B	13/1056	173/7206	0.00615453634748
ko04964	Proximal tubule bicarbonate reclamation	10/1056	29/7206	0.00617831423371
ko04750	Inflammatory mediator regulation of TRP channels	29/1056	122/7206	0.0064120050788
ko04711	Circadian rhythm - fly	6/1056	13/7206	0.00665287619134
ko04214	Apoptosis - fly	3/1056	72/7206	0.00696092274497
ko04217	Necroptosis	14/1056	178/7206	0.00715233613552
ko05219	Bladder cancer	1/1056	48/7206	0.00715296858356
ko04922	Glucagon signaling pathway	30/1056	128/7206	0.00759570128877
ko04010	MAPK signaling pathway	64/1056	321/7206	0.00767979437672
ko04924	Renin secretion	22/1056	86/7206	0.00814271337137
ko05205	Proteoglycans in cancer	25/1056	271/7206	0.00846952168983
ko04745	Phototransduction - fly	12/1056	38/7206	0.00866348224054
ko04620	Toll-like receptor signaling pathway	6/1056	100/7206	0.0100367709681
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1056	14/7206	0.0102188114769
ko03420	Nucleotide excision repair	1/1056	46/7206	0.0107133278747
ko04621	NOD-like receptor signaling pathway	12/1056	157/7206	0.011489053173
ko04974	Protein digestion and absorption	23/1056	96/7206	0.0132060571934
ko04657	IL-17 signaling pathway	5/1056	87/7206	0.0141677775875
ko05130	Pathogenic Escherichia coli infection	4/1056	77/7206	0.0143732092623
ko04612	Antigen processing and presentation	4/1056	77/7206	0.0143732092623
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/1056	79/7206	0.0149896961771
ko03022	Basal transcription factors	1/1056	44/7206	0.0162977911291
ko04014	Ras signaling pathway	55/1056	279/7206	0.0193721585674
ko05416	Viral myocarditis	2/1056	55/7206	0.0193966259139
ko00562	Inositol phosphate metabolism	21/1056	89/7206	0.0227260869947
ko05020	Prion diseases	1/1056	40/7206	0.0235240290285
ko05016	Huntington's disease	20/1056	215/7206	0.023917656816
ko04512	ECM-receptor interaction	19/1056	79/7206	0.0241281103995
ko04210	Apoptosis	16/1056	180/7206	0.0247756466686
ko04932	Non-alcoholic fatty liver disease (NAFLD)	16/1056	182/7206	0.025085741526
ko03015	mRNA surveillance pathway	6/1056	93/7206	0.0254483312783
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1056	59/7206	0.0256180467936
ko04740	Olfactory transduction	19/1056	80/7206	0.0258756385833
ko05162	Measles	9/1056	120/7206	0.0259264821172
ko05131	Shigellosis	5/1056	82/7206	0.0266600751601
ko05012	Parkinson's disease	13/1056	155/7206	0.028252096225
ko04622	RIG-I-like receptor signaling pathway	3/1056	62/7206	0.0284158222235
ko05414	Dilated cardiomyopathy	25/1056	112/7206	0.0299266232039
ko04540	Gap junction	28/1056	128/7206	0.0308903760321
ko04111	Cell cycle - yeast	6/1056	90/7206	0.0341294198305
ko04630	Jak-STAT signaling pathway	11/1056	132/7206	0.0349044786751
ko03410	Base excision repair	1/1056	38/7206	0.0353595958747
ko04142	Lysosome	13/1056	151/7206	0.0355212672944
ko05224	Breast cancer	16/1056	174/7206	0.0389260046093
ko04113	Meiosis - yeast	4/1056	70/7206	0.0392075936059
ko04064	NF-kappa B signaling pathway	7/1056	96/7206	0.0409706546773
ko04260	Cardiac muscle contraction	22/1056	98/7206	0.0423170778041
ko04550	Signaling pathways regulating pluripotency of stem cells	15/1056	165/7206	0.0442286212783
ko05220	Chronic myeloid leukemia	6/1056	85/7206	0.0447211036103
ko05410	Hypertrophic cardiomyopathy (HCM)	22/1056	100/7206	0.0451277567694
ko04973	Carbohydrate digestion and absorption	11/1056	42/7206	0.0460082799578
ko05140	Leishmaniasis	5/1056	75/7206	0.048540664649
ko04664	Fc epsilon RI signaling pathway	5/1056	77/7206	0.0496809149181