ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 28/388 96/7206 5.12455921554e-14 ko04512 ECM-receptor interaction 19/388 79/7206 2.24461825608e-08 ko04260 Cardiac muscle contraction 20/388 98/7206 1.81261701258e-07 ko04740 Olfactory transduction 17/388 80/7206 8.40266885496e-07 ko04727 GABAergic synapse 18/388 110/7206 2.00206399357e-05 ko05410 Hypertrophic cardiomyopathy (HCM) 17/388 100/7206 2.03644906842e-05 ko04978 Mineral absorption 10/388 40/7206 3.60625235481e-05 ko00350 Tyrosine metabolism 9/388 33/7206 4.21089486678e-05 ko04261 Adrenergic signaling in cardiomyocytes 26/388 205/7206 4.57708197804e-05 ko05414 Dilated cardiomyopathy 17/388 112/7206 9.07126454364e-05 ko04964 Proximal tubule bicarbonate reclamation 8/388 29/7206 0.000103736024386 ko05033 Nicotine addiction 11/388 56/7206 0.000158625609307 ko04976 Bile secretion 13/388 80/7206 0.000305025640078 ko04072 Phospholipase D signaling pathway 1/388 197/7206 0.000333165555403 ko04514 Cell adhesion molecules (CAMs) 17/388 130/7206 0.000564074802437 ko00643 Styrene degradation 3/388 4/7206 0.000595003750348 ko04510 Focal adhesion 26/388 240/7206 0.000635802517797 ko04151 PI3K-Akt signaling pathway 37/388 390/7206 0.000708833776618 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/388 79/7206 0.000964835417117 ko04080 Neuroactive ligand-receptor interaction 38/388 423/7206 0.00170089979792 ko04971 Gastric acid secretion 13/388 98/7206 0.00216027093853 ko03013 RNA transport 1/388 166/7206 0.00240980322728 ko05203 Viral carcinogenesis 5/388 277/7206 0.00400846829589 ko04150 mTOR signaling pathway 2/388 184/7206 0.00431758871047 ko04911 Insulin secretion 14/388 117/7206 0.00538159465835 ko04144 Endocytosis 8/388 342/7206 0.00677789505906 ko05032 Morphine addiction 13/388 110/7206 0.00811458002864 ko04726 Serotonergic synapse 15/388 137/7206 0.0108920819937 ko04961 Endocrine and other factor-regulated calcium reabsorption 8/388 59/7206 0.0130769767338 ko05152 Tuberculosis 3/388 187/7206 0.0134249273176 ko04211 Longevity regulating pathway 1/388 123/7206 0.0146045126518 ko04660 T cell receptor signaling pathway 1/388 124/7206 0.0146524439028 ko04745 Phototransduction - fly 6/388 38/7206 0.0149627736534 ko00190 Oxidative phosphorylation 1/388 127/7206 0.0150689712005 ko04742 Taste transduction 8/388 61/7206 0.0158262533539 ko05166 HTLV-I infection 7/388 292/7206 0.0167251762175 ko05322 Systemic lupus erythematosus 2/388 151/7206 0.0173518203939 ko04970 Salivary secretion 11/388 95/7206 0.0177317181248 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/388 182/7206 0.0186906407995 ko04713 Circadian entrainment 14/388 136/7206 0.0188515068634 ko04725 Cholinergic synapse 16/388 160/7206 0.0189217321307 ko04960 Aldosterone-regulated sodium reabsorption 6/388 41/7206 0.0212979372072 ko04110 Cell cycle 2/388 145/7206 0.0244764071011 ko05161 Hepatitis B 3/388 173/7206 0.0256977060916 ko04670 Leukocyte transendothelial migration 15/388 151/7206 0.0259351826997 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/388 5/7206 0.0259442908131 ko05164 Influenza A 3/388 167/7206 0.0355670061179 ko04068 FoxO signaling pathway 3/388 167/7206 0.0355670061179 ko00730 Thiamine metabolism 3/388 14/7206 0.0361930067288 ko04020 Calcium signaling pathway 22/388 265/7206 0.0373195116528 ko04723 Retrograde endocannabinoid signaling 16/388 175/7206 0.0390768649093 ko04744 Phototransduction 5/388 36/7206 0.0420311660196 ko04620 Toll-like receptor signaling pathway 1/388 100/7206 0.0438693128143 ko04914 Progesterone-mediated oocyte maturation 1/388 104/7206 0.0448976917731 ko04141 Protein processing in endoplasmic reticulum 4/388 184/7206 0.0467944544637 ko04060 Cytokine-cytokine receptor interaction 4/388 191/7206 0.0484414035686 ko04380 Osteoclast differentiation 2/388 134/7206 0.0495757137815