ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	100/640	423/7206	3.25035543972e-21
ko05033	Nicotine addiction	31/640	56/7206	8.40500492056e-19
ko04724	Glutamatergic synapse	46/640	152/7206	2.36246776708e-14
ko04974	Protein digestion and absorption	33/640	96/7206	2.39471132183e-12
ko04727	GABAergic synapse	33/640	110/7206	1.57211086927e-10
ko04728	Dopaminergic synapse	45/640	185/7206	1.88523690997e-10
ko04713	Circadian entrainment	36/640	136/7206	1.11068976299e-09
ko04725	Cholinergic synapse	38/640	160/7206	1.039847278e-08
ko05032	Morphine addiction	30/640	110/7206	1.31192525966e-08
ko04976	Bile secretion	24/640	80/7206	5.16286852738e-08
ko04742	Taste transduction	20/640	61/7206	1.32473798446e-07
ko05030	Cocaine addiction	22/640	73/7206	1.70647556097e-07
ko04740	Olfactory transduction	23/640	80/7206	2.33093679613e-07
ko04723	Retrograde endocannabinoid signaling	37/640	175/7206	4.70749014527e-07
ko05031	Amphetamine addiction	24/640	91/7206	7.40957065966e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	21/640	74/7206	9.91248235322e-07
ko04024	cAMP signaling pathway	50/640	279/7206	1.41886335528e-06
ko04978	Mineral absorption	14/640	40/7206	4.31255808709e-06
ko04744	Phototransduction	13/640	36/7206	6.39536629142e-06
ko04911	Insulin secretion	26/640	117/7206	8.42543672044e-06
ko04512	ECM-receptor interaction	20/640	79/7206	1.21481654702e-05
ko04964	Proximal tubule bicarbonate reclamation	11/640	29/7206	1.94186090403e-05
ko04726	Serotonergic synapse	28/640	137/7206	2.30112354345e-05
ko04514	Cell adhesion molecules (CAMs)	27/640	130/7206	2.61509101779e-05
ko03040	Spliceosome	1/640	145/7206	4.10734018023e-05
ko04721	Synaptic vesicle cycle	19/640	80/7206	5.23676846447e-05
ko04614	Renin-angiotensin system	8/640	18/7206	7.24869011139e-05
ko04261	Adrenergic signaling in cardiomyocytes	35/640	205/7206	0.000144751391918
ko04020	Calcium signaling pathway	42/640	265/7206	0.000164038908379
ko04970	Salivary secretion	20/640	95/7206	0.000201541921847
ko03013	RNA transport	3/640	166/7206	0.000265564251906
ko04110	Cell cycle	2/640	145/7206	0.000297443827287
ko05203	Viral carcinogenesis	9/640	277/7206	0.00032288304407
ko04971	Gastric acid secretion	20/640	98/7206	0.000415617065174
ko04120	Ubiquitin mediated proteolysis	2/640	138/7206	0.000420280802302
ko04621	NOD-like receptor signaling pathway	3/640	157/7206	0.000544882527825
ko05166	HTLV-I infection	11/640	292/7206	0.000734282552934
ko04151	PI3K-Akt signaling pathway	54/640	390/7206	0.000906966249794
ko04260	Cardiac muscle contraction	19/640	98/7206	0.000957329144443
ko04972	Pancreatic secretion	21/640	111/7206	0.00101598677475
ko04140	Autophagy - animal	4/640	164/7206	0.00126317983394
ko05164	Influenza A	4/640	167/7206	0.00130192713459
ko05168	Herpes simplex infection	5/640	182/7206	0.00137328073869
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/640	182/7206	0.00137328073869
ko04141	Protein processing in endoplasmic reticulum	5/640	184/7206	0.00140273898116
ko00350	Tyrosine metabolism	9/640	33/7206	0.00178658652902
ko05162	Measles	2/640	120/7206	0.00183823776105
ko00564	Glycerophospholipid metabolism	1/640	99/7206	0.00198448926682
ko05161	Hepatitis B	5/640	173/7206	0.00263578898112
ko04060	Cytokine-cytokine receptor interaction	6/640	191/7206	0.0027203304871
ko04973	Carbohydrate digestion and absorption	10/640	42/7206	0.00305470965173
ko00830	Retinol metabolism	10/640	42/7206	0.00305470965173
ko04924	Renin secretion	16/640	86/7206	0.00363040402019
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/640	59/7206	0.00495871804568
ko05220	Chronic myeloid leukemia	1/640	85/7206	0.00622661281084
ko00190	Oxidative phosphorylation	3/640	127/7206	0.00652317067604
ko04218	Cellular senescence	6/640	177/7206	0.00686171187554
ko04720	Long-term potentiation	17/640	99/7206	0.00690031879568
ko04217	Necroptosis	6/640	178/7206	0.00696035879406
ko05169	Epstein-Barr virus infection	8/640	206/7206	0.00848514594679
ko03008	Ribosome biogenesis in eukaryotes	1/640	79/7206	0.00901749118106
ko04138	Autophagy - yeast	1/640	81/7206	0.00919130110328
ko00983	Drug metabolism - other enzymes	9/640	42/7206	0.0100546009663
ko05016	Huntington's disease	9/640	215/7206	0.0103473906863
ko04142	Lysosome	5/640	151/7206	0.0129261944509
ko04921	Oxytocin signaling pathway	29/640	209/7206	0.0134264841379
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/640	79/7206	0.0144409268901
ko04745	Phototransduction - fly	8/640	38/7206	0.0165379991866
ko04214	Apoptosis - fly	1/640	72/7206	0.0196123261565
ko04022	cGMP-PKG signaling pathway	29/640	216/7206	0.0209847158232
ko00910	Nitrogen metabolism	5/640	19/7206	0.0221244346008
ko04914	Progesterone-mediated oocyte maturation	3/640	104/7206	0.0236902754512
ko04211	Longevity regulating pathway	4/640	123/7206	0.0239266849863
ko04730	Long-term depression	13/640	78/7206	0.0248740937775
ko04150	mTOR signaling pathway	8/640	184/7206	0.0251620174506
ko04960	Aldosterone-regulated sodium reabsorption	8/640	41/7206	0.0255598981947
ko05152	Tuberculosis	8/640	187/7206	0.0256283917464
ko04010	MAPK signaling pathway	40/640	321/7206	0.0267039305843
ko04068	FoxO signaling pathway	7/640	167/7206	0.0272551893747
ko05205	Proteoglycans in cancer	14/640	271/7206	0.0287539409985
ko00410	beta-Alanine metabolism	7/640	35/7206	0.0315824433316
ko04371	Apelin signaling pathway	24/640	177/7206	0.0320253679254
ko00053	Ascorbate and aldarate metabolism	5/640	22/7206	0.0401963052881
ko04330	Notch signaling pathway	1/640	62/7206	0.0409435782031
ko04622	RIG-I-like receptor signaling pathway	1/640	62/7206	0.0409435782031
ko04670	Leukocyte transendothelial migration	21/640	151/7206	0.0410367005106
ko00561	Glycerolipid metabolism	1/640	63/7206	0.0415538026116
ko00643	Styrene degradation	2/640	4/7206	0.0418654649003
ko04630	Jak-STAT signaling pathway	5/640	132/7206	0.0425754987073
ko04510	Focal adhesion	30/640	240/7206	0.0496445827172