ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 13/130 30/7206 1.07768099801e-15 ko04060 Cytokine-cytokine receptor interaction 21/130 191/7206 1.83589853176e-11 ko05164 Influenza A 17/130 167/7206 6.00424286733e-09 ko04612 Antigen processing and presentation 12/130 77/7206 9.67803671184e-09 ko05168 Herpes simplex infection 17/130 182/7206 2.21807655503e-08 ko05320 Autoimmune thyroid disease 8/130 29/7206 2.82234915712e-08 ko05152 Tuberculosis 17/130 187/7206 3.32963620634e-08 ko05321 Inflammatory bowel disease (IBD) 10/130 56/7206 4.54434042122e-08 ko04650 Natural killer cell mediated cytotoxicity 12/130 97/7206 1.38271699416e-07 ko05330 Allograft rejection 7/130 24/7206 1.41827837321e-07 ko05162 Measles 13/130 120/7206 1.99575858502e-07 ko05145 Toxoplasmosis 12/130 126/7206 2.4235255657e-06 ko04659 Th17 cell differentiation 11/130 106/7206 2.79603215308e-06 ko04672 Intestinal immune network for IgA production 7/130 37/7206 3.47062699207e-06 ko04621 NOD-like receptor signaling pathway 13/130 157/7206 4.39127088118e-06 ko04145 Phagosome 13/130 162/7206 6.21428118713e-06 ko05140 Leishmaniasis 9/130 75/7206 7.04587699326e-06 ko04620 Toll-like receptor signaling pathway 10/130 100/7206 1.12874979163e-05 ko05332 Graft-versus-host disease 5/130 18/7206 1.25549155056e-05 ko05161 Hepatitis B 13/130 173/7206 1.27402747468e-05 ko04217 Necroptosis 13/130 178/7206 1.7321185703e-05 ko04630 Jak-STAT signaling pathway 11/130 132/7206 2.33946319185e-05 ko05133 Pertussis 9/130 87/7206 2.39777240204e-05 ko03050 Proteasome 7/130 54/7206 4.62739546161e-05 ko04658 Th1 and Th2 cell differentiation 9/130 96/7206 5.28676650682e-05 ko04064 NF-kappa B signaling pathway 9/130 96/7206 5.28676650682e-05 ko04660 T cell receptor signaling pathway 10/130 124/7206 7.37995844998e-05 ko05323 Rheumatoid arthritis 8/130 89/7206 0.000187499355893 ko05310 Asthma 4/130 17/7206 0.000200614907034 ko04940 Type I diabetes mellitus 5/130 32/7206 0.000240932543051 ko04380 Osteoclast differentiation 9/130 134/7206 0.000668649095366 ko04622 RIG-I-like receptor signaling pathway 6/130 62/7206 0.000825423012729 ko04062 Chemokine signaling pathway 11/130 201/7206 0.000967008594664 ko05144 Malaria 5/130 45/7206 0.00121198074939 ko04610 Complement and coagulation cascades 6/130 79/7206 0.00290916900076 ko05416 Viral myocarditis 5/130 55/7206 0.00298951034315 ko05150 Staphylococcus aureus infection 4/130 36/7206 0.00380996733524 ko04640 Hematopoietic cell lineage 5/130 64/7206 0.00576091843146 ko05167 Kaposi's sarcoma-associated herpesvirus infection 9/130 191/7206 0.00746851032884 ko05142 Chagas disease (American trypanosomiasis) 7/130 130/7206 0.0089193306003 ko04514 Cell adhesion molecules (CAMs) 7/130 130/7206 0.0089193306003 ko04210 Apoptosis 8/130 180/7206 0.0158696647357 ko04670 Leukocyte transendothelial migration 7/130 151/7206 0.0191203516989 ko05160 Hepatitis C 7/130 153/7206 0.0203972726912 ko05132 Salmonella infection 5/130 98/7206 0.0316923918186 ko05146 Amoebiasis 5/130 99/7206 0.0329121213341 ko05020 Prion diseases 3/130 40/7206 0.0349033058893 ko04623 Cytosolic DNA-sensing pathway 3/130 41/7206 0.0371763079138 ko05134 Legionellosis 4/130 74/7206 0.0441976181379