ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	116/573	423/7206	9.50440561114e-36
ko05033	Nicotine addiction	39/573	56/7206	1.05206637913e-30
ko04724	Glutamatergic synapse	58/573	152/7206	5.30028539074e-26
ko04728	Dopaminergic synapse	56/573	185/7206	1.65820070979e-19
ko04721	Synaptic vesicle cycle	36/573	80/7206	2.38935102189e-19
ko04723	Retrograde endocannabinoid signaling	52/573	175/7206	8.72025340467e-18
ko05032	Morphine addiction	40/573	110/7206	2.36579528491e-17
ko04713	Circadian entrainment	44/573	136/7206	9.48779564736e-17
ko04727	GABAergic synapse	39/573	110/7206	1.64900036886e-16
ko04024	cAMP signaling pathway	63/573	279/7206	7.30780864856e-15
ko05031	Amphetamine addiction	30/573	91/7206	4.88650095085e-12
ko04725	Cholinergic synapse	40/573	160/7206	2.82464523012e-11
ko04911	Insulin secretion	32/573	117/7206	2.40394212619e-10
ko04742	Taste transduction	22/573	61/7206	5.03663738981e-10
ko05014	Amyotrophic lateral sclerosis (ALS)	24/573	74/7206	1.01081476728e-09
ko04720	Long-term potentiation	28/573	99/7206	1.41521395613e-09
ko04261	Adrenergic signaling in cardiomyocytes	43/573	205/7206	2.0734055762e-09
ko05030	Cocaine addiction	23/573	73/7206	4.28778098569e-09
ko04726	Serotonergic synapse	33/573	137/7206	4.47453035161e-09
ko04020	Calcium signaling pathway	49/573	265/7206	1.76897575707e-08
ko04921	Oxytocin signaling pathway	41/573	209/7206	6.10527155438e-08
ko04010	MAPK signaling pathway	52/573	321/7206	4.65800871075e-07
ko04966	Collecting duct acid secretion	11/573	26/7206	1.87052013746e-06
ko04970	Salivary secretion	22/573	95/7206	3.53336502257e-06
ko04060	Cytokine-cytokine receptor interaction	1/573	191/7206	4.00256126682e-06
ko04514	Cell adhesion molecules (CAMs)	26/573	130/7206	8.56408611591e-06
ko04925	Aldosterone synthesis and secretion	21/573	105/7206	6.25541710445e-05
ko04971	Gastric acid secretion	20/573	98/7206	6.91455415601e-05
ko03040	Spliceosome	1/573	145/7206	0.000136627967067
ko05203	Viral carcinogenesis	7/573	277/7206	0.000164404450372
ko04120	Ubiquitin mediated proteolysis	1/573	138/7206	0.000200057524641
ko05164	Influenza A	2/573	167/7206	0.000216469585934
ko04022	cGMP-PKG signaling pathway	33/573	216/7206	0.000272029866464
ko05110	Vibrio cholerae infection	14/573	63/7206	0.000333875737456
ko04730	Long-term depression	16/573	78/7206	0.000340806357194
ko04972	Pancreatic secretion	20/573	111/7206	0.000500892656023
ko05162	Measles	1/573	120/7206	0.000952590622266
ko04550	Signaling pathways regulating pluripotency of stem cells	3/573	165/7206	0.00115646427267
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/573	79/7206	0.00120819660598
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/573	92/7206	0.00127170951213
ko04915	Estrogen signaling pathway	21/573	131/7206	0.00166012585132
ko05168	Herpes simplex infection	4/573	182/7206	0.00192421475533
ko04260	Cardiac muscle contraction	17/573	98/7206	0.0019537278738
ko04626	Plant-pathogen interaction	6/573	18/7206	0.00199409440585
ko04745	Phototransduction - fly	9/573	38/7206	0.00239722573441
ko04350	TGF-beta signaling pathway	1/573	103/7206	0.00298344064277
ko05322	Systemic lupus erythematosus	3/573	151/7206	0.00333712958774
ko05323	Rheumatoid arthritis	15/573	89/7206	0.00468090589795
ko05205	Proteoglycans in cancer	10/573	271/7206	0.00573722486668
ko04621	NOD-like receptor signaling pathway	4/573	157/7206	0.00686353674236
ko05034	Alcoholism	30/573	238/7206	0.0101963053932
ko04072	Phospholipase D signaling pathway	26/573	197/7206	0.0103602681575
ko05166	HTLV-I infection	12/573	292/7206	0.0107261377415
ko05215	Prostate cancer	2/573	111/7206	0.0117870077847
ko04145	Phagosome	22/573	162/7206	0.0118159929936
ko05169	Epstein-Barr virus infection	7/573	206/7206	0.0122378724484
ko04014	Ras signaling pathway	34/573	279/7206	0.0123963280185
ko00680	Methane metabolism	7/573	34/7206	0.0157355779525
ko05010	Alzheimer's disease	26/573	202/7206	0.0165090530758
ko04140	Autophagy - animal	5/573	164/7206	0.0181199999506
ko03008	Ribosome biogenesis in eukaryotes	1/573	79/7206	0.0198244385668
ko05414	Dilated cardiomyopathy	16/573	112/7206	0.0202767412532
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/573	14/7206	0.0208079427765
ko05161	Hepatitis B	6/573	173/7206	0.0225027411252
ko05146	Amoebiasis	2/573	99/7206	0.0231531737055
ko04924	Renin secretion	13/573	86/7206	0.024178448372
ko04931	Insulin resistance	4/573	137/7206	0.0244391472374
ko04750	Inflammatory mediator regulation of TRP channels	17/573	122/7206	0.0258786438148
ko04360	Axon guidance	28/573	233/7206	0.0259517096085
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/573	15/7206	0.0266328434149
ko04510	Focal adhesion	10/573	240/7206	0.0279446289388
ko04612	Antigen processing and presentation	1/573	77/7206	0.0303168940755
ko04540	Gap junction	17/573	128/7206	0.031340506052
ko04630	Jak-STAT signaling pathway	4/573	132/7206	0.0332878348391
ko04740	Olfactory transduction	12/573	80/7206	0.0335153941114
ko04978	Mineral absorption	7/573	40/7206	0.0361662785347
ko04930	Type II diabetes mellitus	9/573	54/7206	0.0363813132381
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/573	182/7206	0.0365469109203
ko04141	Protein processing in endoplasmic reticulum	7/573	184/7206	0.0369506511362
ko04114	Oocyte meiosis	18/573	139/7206	0.0377636258972
ko05200	Pathways in cancer	27/573	492/7206	0.0378305392513
ko03013	RNA transport	6/573	166/7206	0.0403327756297
ko05217	Basal cell carcinoma	1/573	68/7206	0.0415476116113
ko04214	Apoptosis - fly	1/573	72/7206	0.0439583674541
ko00513	Various types of N-glycan biosynthesis	7/573	42/7206	0.0456828388335
ko04146	Peroxisome	2/573	89/7206	0.0460852687903
ko04962	Vasopressin-regulated water reabsorption	9/573	58/7206	0.0461265595834
ko00240	Pyrimidine metabolism	3/573	110/7206	0.0476703249451
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/573	59/7206	0.0493124646698
ko04070	Phosphatidylinositol signaling system	15/573	112/7206	0.0495015574747