ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	79/765	152/7206	5.75889100465e-38
ko05033	Nicotine addiction	47/765	56/7206	1.36299597894e-37
ko04080	Neuroactive ligand-receptor interaction	138/765	423/7206	2.60061098876e-37
ko05032	Morphine addiction	58/765	110/7206	1.77701521065e-28
ko04727	GABAergic synapse	55/765	110/7206	1.54847529647e-25
ko04723	Retrograde endocannabinoid signaling	67/765	175/7206	1.46493464776e-22
ko04713	Circadian entrainment	58/765	136/7206	2.00306273941e-22
ko04728	Dopaminergic synapse	68/765	185/7206	1.0364297644e-21
ko04024	cAMP signaling pathway	81/765	279/7206	2.71675915404e-18
ko04725	Cholinergic synapse	55/765	160/7206	3.06281764641e-16
ko04020	Calcium signaling pathway	72/765	265/7206	1.11203752075e-14
ko04911	Insulin secretion	43/765	117/7206	4.0257528476e-14
ko04721	Synaptic vesicle cycle	34/765	80/7206	1.42162022632e-13
ko04726	Serotonergic synapse	45/765	137/7206	1.07287122121e-12
ko04720	Long-term potentiation	37/765	99/7206	1.38766470006e-12
ko05031	Amphetamine addiction	35/765	91/7206	2.13348132946e-12
ko05030	Cocaine addiction	29/765	73/7206	6.7375968588e-11
ko04261	Adrenergic signaling in cardiomyocytes	54/765	205/7206	1.01695816095e-10
ko04742	Taste transduction	26/765	61/7206	1.01902841928e-10
ko04921	Oxytocin signaling pathway	55/765	209/7206	1.15654843389e-10
ko04744	Phototransduction	18/765	36/7206	3.45242838658e-09
ko04010	MAPK signaling pathway	67/765	321/7206	4.22349811232e-08
ko04925	Aldosterone synthesis and secretion	31/765	105/7206	6.45751698128e-08
ko05203	Viral carcinogenesis	6/765	277/7206	7.66053778637e-08
ko04970	Salivary secretion	29/765	95/7206	7.66536443901e-08
ko04060	Cytokine-cytokine receptor interaction	2/765	191/7206	2.56301715166e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/765	74/7206	2.9141571671e-07
ko04514	Cell adhesion molecules (CAMs)	33/765	130/7206	1.59258847749e-06
ko03040	Spliceosome	1/765	145/7206	2.03786683829e-06
ko04972	Pancreatic secretion	29/765	111/7206	2.82991885098e-06
ko04072	Phospholipase D signaling pathway	43/765	197/7206	3.03469628614e-06
ko04971	Gastric acid secretion	26/765	98/7206	6.79924205819e-06
ko04022	cGMP-PKG signaling pathway	44/765	216/7206	1.56046819869e-05
ko04730	Long-term depression	21/765	78/7206	4.07354256375e-05
ko05168	Herpes simplex infection	5/765	182/7206	0.000121625057741
ko04070	Phosphatidylinositol signaling system	26/765	112/7206	0.000129850029493
ko04260	Cardiac muscle contraction	23/765	98/7206	0.000194787018785
ko04915	Estrogen signaling pathway	28/765	131/7206	0.000260034910041
ko04740	Olfactory transduction	20/765	80/7206	0.000308513704712
ko05164	Influenza A	5/765	167/7206	0.000330110767904
ko04360	Axon guidance	42/765	233/7206	0.000488878774928
ko05169	Epstein-Barr virus infection	8/765	206/7206	0.000531758721809
ko04110	Cell cycle	4/765	145/7206	0.000581897847819
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/765	79/7206	0.000595830830892
ko04621	NOD-like receptor signaling pathway	5/765	157/7206	0.000912251855906
ko04141	Protein processing in endoplasmic reticulum	7/765	184/7206	0.000983889166395
ko05414	Dilated cardiomyopathy	23/765	112/7206	0.00166676383616
ko05322	Systemic lupus erythematosus	5/765	151/7206	0.00183455432897
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/765	14/7206	0.00199132984889
ko04014	Ras signaling pathway	46/765	279/7206	0.00203362057938
ko04630	Jak-STAT signaling pathway	4/765	132/7206	0.00236054189664
ko04918	Thyroid hormone synthesis	18/765	86/7206	0.00415389245509
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/765	59/7206	0.004164446694
ko04612	Antigen processing and presentation	1/765	77/7206	0.00419017070486
ko05231	Choline metabolism in cancer	25/765	134/7206	0.00431435598106
ko04140	Autophagy - animal	7/765	164/7206	0.00458689156903
ko04120	Ubiquitin mediated proteolysis	5/765	138/7206	0.00473242258613
ko04146	Peroxisome	2/765	89/7206	0.00507894745686
ko04745	Phototransduction - fly	10/765	38/7206	0.00510066890065
ko05034	Alcoholism	39/765	238/7206	0.00519392075669
ko05162	Measles	4/765	120/7206	0.00639225266133
ko04750	Inflammatory mediator regulation of TRP channels	23/765	122/7206	0.00676073837061
ko05205	Proteoglycans in cancer	16/765	271/7206	0.00864662652879
ko04964	Proximal tubule bicarbonate reclamation	8/765	29/7206	0.00877814363271
ko04015	Rap1 signaling pathway	43/765	278/7206	0.00973296557429
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/765	182/7206	0.00991933083341
ko03013	RNA transport	8/765	166/7206	0.010504051596
ko04973	Carbohydrate digestion and absorption	10/765	42/7206	0.0107617430934
ko04640	Hematopoietic cell lineage	1/765	64/7206	0.0126430925264
ko04540	Gap junction	23/765	128/7206	0.012702638764
ko04550	Signaling pathways regulating pluripotency of stem cells	8/765	165/7206	0.0142587199312
ko05010	Alzheimer's disease	32/765	202/7206	0.0198554460496
ko00310	Lysine degradation	2/765	73/7206	0.0212970092293
ko04924	Renin secretion	16/765	86/7206	0.0214615292525
ko04217	Necroptosis	10/765	178/7206	0.0260719300792
ko04976	Bile secretion	15/765	80/7206	0.0264659413275
ko04930	Type II diabetes mellitus	11/765	54/7206	0.0265700478261
ko00480	Glutathione metabolism	1/765	55/7206	0.0266557869253
ko05321	Inflammatory bowel disease (IBD)	1/765	56/7206	0.0269469872907
ko03320	PPAR signaling pathway	2/765	69/7206	0.0302584898387
ko03018	RNA degradation	3/765	84/7206	0.031402802854
ko04214	Apoptosis - fly	2/765	72/7206	0.031469648699
ko00230	Purine metabolism	30/765	194/7206	0.0327581768628
ko05161	Hepatitis B	10/765	173/7206	0.0335349231989
ko04371	Apelin signaling pathway	28/765	177/7206	0.0344544183234
ko00562	Inositol phosphate metabolism	16/765	89/7206	0.0352390307488
ko04062	Chemokine signaling pathway	31/765	201/7206	0.0354783538369
ko04064	NF-kappa B signaling pathway	4/765	96/7206	0.0430414611661
ko03008	Ribosome biogenesis in eukaryotes	3/765	79/7206	0.0434174008986
ko04137	Mitophagy - animal	3/765	82/7206	0.0445499805855
ko05410	Hypertrophic cardiomyopathy (HCM)	17/765	100/7206	0.0478506595041
ko04210	Apoptosis	11/765	180/7206	0.0490919737775