ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 9/226 20/7206 3.11687141148e-09 ko00380 Tryptophan metabolism 10/226 50/7206 2.57826984594e-06 ko00350 Tyrosine metabolism 8/226 33/7206 5.82985379497e-06 ko00360 Phenylalanine metabolism 6/226 17/7206 8.24917587652e-06 ko05150 Staphylococcus aureus infection 8/226 36/7206 1.17134444917e-05 ko00362 Benzoate degradation 4/226 6/7206 1.34537165953e-05 ko04060 Cytokine-cytokine receptor interaction 18/226 191/7206 2.75803953951e-05 ko00590 Arachidonic acid metabolism 9/226 52/7206 2.84264657025e-05 ko03320 PPAR signaling pathway 10/226 69/7206 5.06299372948e-05 ko04610 Complement and coagulation cascades 10/226 79/7206 0.000163081722469 ko00950 Isoquinoline alkaloid biosynthesis 4/226 10/7206 0.000170506295669 ko00140 Steroid hormone biosynthesis 7/226 41/7206 0.000246105896415 ko05340 Primary immunodeficiency 6/226 30/7206 0.000281072204264 ko04672 Intestinal immune network for IgA production 6/226 37/7206 0.00091613677205 ko05168 Herpes simplex infection 14/226 182/7206 0.0016744966635 ko05321 Inflammatory bowel disease (IBD) 7/226 56/7206 0.00170413682758 ko00983 Drug metabolism - other enzymes 6/226 42/7206 0.00181428884637 ko00592 alpha-Linolenic acid metabolism 4/226 19/7206 0.00251922818761 ko00071 Fatty acid degradation 6/226 45/7206 0.00260530714382 ko04080 Neuroactive ligand-receptor interaction 4/226 423/7206 0.00380737868005 ko05162 Measles 10/226 120/7206 0.00429627536119 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/226 4/7206 0.00563563594006 ko00643 Styrene degradation 2/226 4/7206 0.00563563594006 ko00965 Betalain biosynthesis 2/226 4/7206 0.00563563594006 ko04630 Jak-STAT signaling pathway 10/226 132/7206 0.00834579330274 ko00281 Geraniol degradation 2/226 5/7206 0.00919901526424 ko04974 Protein digestion and absorption 8/226 96/7206 0.0102540729 ko00330 Arginine and proline metabolism 6/226 61/7206 0.011736259416 ko00561 Glycerolipid metabolism 6/226 63/7206 0.0136407146511 ko04621 NOD-like receptor signaling pathway 11/226 157/7206 0.0165566668645 ko05133 Pertussis 7/226 87/7206 0.019005802796 ko00640 Propanoate metabolism 4/226 34/7206 0.0209012650931 ko04146 Peroxisome 7/226 89/7206 0.0212726366088 ko04972 Pancreatic secretion 8/226 111/7206 0.0229596300574 ko04975 Fat digestion and absorption 4/226 35/7206 0.0230342959562 ko00500 Starch and sucrose metabolism 4/226 35/7206 0.0230342959562 ko00310 Lysine degradation 6/226 73/7206 0.0264459773471 ko00100 Steroid biosynthesis 3/226 21/7206 0.0266833318123 ko00982 Drug metabolism - cytochrome P450 4/226 37/7206 0.0276850133765 ko05140 Leishmaniasis 6/226 75/7206 0.0297247124149 ko04658 Th1 and Th2 cell differentiation 7/226 96/7206 0.0306761334282 ko04064 NF-kappa B signaling pathway 7/226 96/7206 0.0306761334282 ko00901 Indole alkaloid biosynthesis 1/226 1/7206 0.0313627532612 ko00401 Novobiocin biosynthesis 1/226 1/7206 0.0313627532612 ko04390 Hippo signaling pathway 1/226 188/7206 0.031686033131 ko04612 Antigen processing and presentation 6/226 77/7206 0.0332598927342 ko04360 Axon guidance 2/226 233/7206 0.0351422174023 ko04620 Toll-like receptor signaling pathway 7/226 100/7206 0.0371419400372 ko00072 Synthesis and degradation of ketone bodies 2/226 10/7206 0.0373300270904 ko01212 Fatty acid metabolism 5/226 60/7206 0.0392526428902 ko00830 Retinol metabolism 4/226 42/7206 0.0416051393485 ko00340 Histidine metabolism 3/226 25/7206 0.0421269047695 ko04622 RIG-I-like receptor signaling pathway 5/226 62/7206 0.0442573672857 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 2/226 11/7206 0.0446993651096 ko05224 Breast cancer 1/226 174/7206 0.0453938581276 ko04723 Retrograde endocannabinoid signaling 1/226 175/7206 0.0455169994701 ko00650 Butanoate metabolism 3/226 26/7206 0.0465541755013 ko04310 Wnt signaling pathway 1/226 181/7206 0.0470968565877 ko05205 Proteoglycans in cancer 3/226 271/7206 0.0492664288576