ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	33/585	56/7206	2.34085516157e-22
ko04724	Glutamatergic synapse	47/585	152/7206	1.42073670182e-16
ko04727	GABAergic synapse	37/585	110/7206	1.37484554622e-14
ko04721	Synaptic vesicle cycle	30/585	80/7206	1.73157269408e-13
ko05032	Morphine addiction	35/585	110/7206	4.76397038429e-13
ko04728	Dopaminergic synapse	47/585	185/7206	5.43994472675e-13
ko04080	Neuroactive ligand-receptor interaction	79/585	423/7206	5.56266497818e-13
ko04723	Retrograde endocannabinoid signaling	44/585	175/7206	4.56621885921e-12
ko04024	cAMP signaling pathway	58/585	279/7206	9.32857660044e-12
ko04713	Circadian entrainment	34/585	136/7206	1.56645356677e-09
ko04744	Phototransduction	16/585	36/7206	4.5846950666e-09
ko04360	Axon guidance	45/585	233/7206	2.69485199275e-08
ko04725	Cholinergic synapse	34/585	160/7206	1.2585482298e-07
ko05030	Cocaine addiction	21/585	73/7206	1.70886222714e-07
ko04514	Cell adhesion molecules (CAMs)	29/585	130/7206	3.66013904936e-07
ko05203	Viral carcinogenesis	4/585	277/7206	1.52939720026e-06
ko04911	Insulin secretion	26/585	117/7206	1.59659537568e-06
ko04726	Serotonergic synapse	28/585	137/7206	3.71127004127e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	17/585	74/7206	6.5639274539e-05
ko03040	Spliceosome	1/585	145/7206	9.05754670781e-05
ko05031	Amphetamine addiction	19/585	91/7206	9.98400526357e-05
ko04010	MAPK signaling pathway	45/585	321/7206	0.000227349000724
ko04261	Adrenergic signaling in cardiomyocytes	32/585	205/7206	0.000361343167885
ko01200	Carbon metabolism	1/585	128/7206	0.000440064779878
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/585	14/7206	0.00047560056056
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/585	79/7206	0.000499864342638
ko04060	Cytokine-cytokine receptor interaction	4/585	191/7206	0.000666253562706
ko05169	Epstein-Barr virus infection	5/585	206/7206	0.00103869279792
ko04720	Long-term potentiation	18/585	99/7206	0.00110706128136
ko04120	Ubiquitin mediated proteolysis	2/585	138/7206	0.0013424707592
ko05205	Proteoglycans in cancer	9/585	271/7206	0.00199149226482
ko04742	Taste transduction	12/585	61/7206	0.00317462812369
ko04140	Autophagy - animal	4/585	164/7206	0.00355252800457
ko03013	RNA transport	4/585	166/7206	0.00359264556855
ko05164	Influenza A	4/585	167/7206	0.00364003636182
ko04141	Protein processing in endoplasmic reticulum	5/585	184/7206	0.00373317987406
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	7/585	26/7206	0.00376234195022
ko05146	Amoebiasis	1/585	99/7206	0.00446861782752
ko04611	Platelet activation	4/585	163/7206	0.00515451216116
ko05162	Measles	2/585	120/7206	0.0059362115427
ko04621	NOD-like receptor signaling pathway	4/585	157/7206	0.00701944080479
ko00240	Pyrimidine metabolism	2/585	110/7206	0.00800981181761
ko05322	Systemic lupus erythematosus	4/585	151/7206	0.0095686787562
ko04972	Pancreatic secretion	17/585	111/7206	0.0123972683465
ko05168	Herpes simplex infection	6/585	182/7206	0.0126218745386
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/585	182/7206	0.0126218745386
ko04919	Thyroid hormone signaling pathway	4/585	143/7206	0.0129507283987
ko00515	Mannose type O-glycan biosynthesis	6/585	25/7206	0.0129995212237
ko04110	Cell cycle	4/585	145/7206	0.0130489848616
ko03018	RNA degradation	1/585	84/7206	0.0138578591374
ko01230	Biosynthesis of amino acids	1/585	85/7206	0.0141755921703
ko04260	Cardiac muscle contraction	15/585	98/7206	0.0143610085056
ko04350	TGF-beta signaling pathway	2/585	103/7206	0.0164611987794
ko04217	Necroptosis	6/585	178/7206	0.0170854824478
ko04391	Hippo signaling pathway - fly	14/585	90/7206	0.0173398626793
ko04211	Longevity regulating pathway	3/585	123/7206	0.0179984500581
ko04066	HIF-1 signaling pathway	3/585	123/7206	0.0179984500581
ko04014	Ras signaling pathway	34/585	279/7206	0.0181035647394
ko01524	Platinum drug resistance	1/585	76/7206	0.0196590294145
ko04612	Antigen processing and presentation	1/585	77/7206	0.0196829326748
ko05414	Dilated cardiomyopathy	16/585	112/7206	0.02249326026
ko04910	Insulin signaling pathway	6/585	172/7206	0.0226387232739
ko04064	NF-kappa B signaling pathway	2/585	96/7206	0.0229142676414
ko04921	Oxytocin signaling pathway	26/585	209/7206	0.0278281563951
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/585	15/7206	0.0285055734583
ko04214	Apoptosis - fly	1/585	72/7206	0.0285900279638
ko00010	Glycolysis / Gluconeogenesis	1/585	74/7206	0.0292477405331
ko04922	Glucagon signaling pathway	4/585	128/7206	0.0329623502893
ko05215	Prostate cancer	3/585	111/7206	0.0337142118037
ko05206	MicroRNAs in cancer	7/585	177/7206	0.0363599996664
ko04218	Cellular senescence	7/585	177/7206	0.0363599996664
ko04210	Apoptosis	7/585	180/7206	0.0367658039204
ko05410	Hypertrophic cardiomyopathy (HCM)	14/585	100/7206	0.040315951808
ko05223	Non-small cell lung cancer	1/585	66/7206	0.0413778052801
ko01521	EGFR tyrosine kinase inhibitor resistance	3/585	106/7206	0.04646795753
ko04146	Peroxisome	2/585	89/7206	0.0471346005168
ko05418	Fluid shear stress and atherosclerosis	7/585	173/7206	0.0475764393032
ko05161	Hepatitis B	7/585	173/7206	0.0475764393032